Protein: RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 (EC 3.1.3.16) (RNA polymerase II-associated protein 2)

Gene: RPAP2
Organism: Homo sapiens
Interactions: 153
UniProt ID: Q8IXW5

Gene Ontology (top 5):
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

583745

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

4

1

High-throughput

0.909

High

624954

RPB1
DNA-directed RNA polymerase II subunit RPB1

4

3

Small-scale

0.899

High

156037

RPC1
DNA-directed RNA polymerase III subunit RPC1

2

3

High-throughput

0.754

High

913918

RPB7
DNA-directed RNA polymerase II subunit RPB7

6

2

High-throughput

0.736

High

1221368

GPN1
GPN-loop GTPase 1

6

3

High-throughput

0.736

High

1221370

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

5

3

Small-scale

0.727

High

1221379

PIHD1
PIH1 domain-containing protein 1

10

0

Small-scale

0.722

High

181435

RPB4
DNA-directed RNA polymerase II subunit RPB4

5

1

High-throughput

0.722

High

854439

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

4

2

High-throughput

0.699

High

897562

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

4

1

High-throughput

0.699

High

583520

RPB3
DNA-directed RNA polymerase II subunit RPB3

4

2

High-throughput

0.694

High

1221383

UXT
Protein UXT

5

0

High-throughput

0.688

High

1221390

GPN3
GPN-loop GTPase 3

6

3

High-throughput

0.672

High

676935

RPB2
DNA-directed RNA polymerase II subunit RPB2

3

3

High-throughput

0.667

High

737910

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

3

1

High-throughput

0.667

High

854328

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

3

1

High-throughput

0.667

High

1221392

RUVB2
RuvB-like 2

3

1

High-throughput

0.667

High

295648

RMP
Unconventional prefoldin RPB5 interactor 1

4

0

High-throughput

0.657

High

125568

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

3

3

Small-scale

0.656

High

1221349

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

2

3

Small-scale

0.649

High

1076176

MED1
Mediator of RNA polymerase II transcription subunit 1

3

0

High-throughput

0.646

High

285165

DXO
Decapping and exoribonuclease protein

3

0

High-throughput

0.638

High

738856

RPB9
DNA-directed RNA polymerase II subunit RPB9

2

2

High-throughput

0.628

High

1221361

RPAP3
RNA polymerase II-associated protein 3

3

0

High-throughput

0.628

High

1221372

PDRG1
p53 and DNA damage-regulated protein 1

3

0

High-throughput

0.628

High

1221373

MED17
Mediator of RNA polymerase II transcription subunit 17

3

0

High-throughput

0.628

High

317133

RPA1
DNA-directed RNA polymerase I subunit RPA1

1

3

High-throughput

0.618

High

246586

MCE1
mRNA-capping enzyme

3

0

High-throughput

0.613

High

1221369

MED4
Mediator of RNA polymerase II transcription subunit 4

3

0

High-throughput

0.613

High

864961

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

2

1

High-throughput

0.611

High

921137

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

2

1

High-throughput

0.611

High

48696

MED19
Mediator of RNA polymerase II transcription subunit 19

3

0

High-throughput

0.606

High

230393

ZC3H1
Zinc finger C3H1 domain-containing protein

2

0

High-throughput

0.602

High

638340

RBTN2
Rhombotin-2

2

0

High-throughput

0.602

High

1221342

CPNE2
Copine-2

2

0

High-throughput

0.602

High

1221354

MED18
Mediator of RNA polymerase II transcription subunit 18

2

0

High-throughput

0.602

High

1221380

ASB6
Ankyrin repeat and SOCS box protein 6

2

0

High-throughput

0.602

High

1221389

PFD2
Prefoldin subunit 2

2

0

High-throughput

0.602

High

473911

GRL1A
DNA-directed RNA polymerase II subunit GRINL1A

3

0

High-throughput

0.585

High

1037070

MED21
Mediator of RNA polymerase II transcription subunit 21

2

0

High-throughput

0.585

High

1221360

MED28
Mediator of RNA polymerase II transcription subunit 28

2

0

High-throughput

0.585

High

749661

BRCA1
Breast cancer type 1 susceptibility protein

2

1

High-throughput

0.584

High

1221376

RPC2
DNA-directed RNA polymerase III subunit RPC2

2

3

High-throughput

0.584

High

1221365

PKHF2
Pleckstrin homology domain-containing family F member 2

2

0

High-throughput

0.580

High

1221375

RPC5
DNA-directed RNA polymerase III subunit RPC5

2

0

High-throughput

0.559

High

1221377

MED9
Mediator of RNA polymerase II transcription subunit 9

2

0

High-throughput

0.559

High

313446

MED26
Mediator of RNA polymerase II transcription subunit 26

2

0

High-throughput

0.547

High

1137930

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

1

2

High-throughput

0.536

High

1221355

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

1

High-throughput

0.536

High

1221359

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

3

High-throughput

0.536

High

1221364

ECT2
Protein ECT2

1

1

High-throughput

0.536

High

171647

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.513

High

206632

MED7
Mediator of RNA polymerase II transcription subunit 7

1

0

High-throughput

0.513

High

575780

VINC
Vinculin

1

0

High-throughput

0.513

High

608875

SPR1B
Cornifin-B

1

0

High-throughput

0.513

High

1221340

FGF11
Fibroblast growth factor 11

1

0

High-throughput

0.513

High

1221341

ARMC5
Armadillo repeat-containing protein 5

1

0

High-throughput

0.513

High

1221344

MED30
Mediator of RNA polymerase II transcription subunit 30

1

0

High-throughput

0.513

High

1221351

CRML
Protein cramped-like

1

0

High-throughput

0.513

High

1221393

MED31
Mediator of RNA polymerase II transcription subunit 31

1

0

High-throughput

0.513

High

808182

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

3

High-throughput

0.501

High

1221346

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

3

High-throughput

0.501

High

1030343

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.493

High

1221352

TCPQM
T-complex protein 1 subunit theta-like 2

1

1

High-throughput

0.489

High

1221357

RPB1B
DNA-directed RNA polymerase II subunit RPB11-b1

1

2

High-throughput

0.489

High

162967

XPO1
Exportin-1

1

2

High-throughput

0.479

High

169892

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

2

High-throughput

0.479

High

225398

MED14
Mediator of RNA polymerase II transcription subunit 14

1

1

High-throughput

0.479

High

228000

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

267522

KHDR3
KH domain-containing, RNA-binding, signal transduction-associated protein 3

1

1

High-throughput

0.479

High

295009

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

295540

RECQ5
ATP-dependent DNA helicase Q5

1

1

High-throughput

0.479

High

443641

VIME
Vimentin

1

1

High-throughput

0.479

High

573356

TCPA
T-complex protein 1 subunit alpha

1

1

High-throughput

0.479

High

808760

YAP1
Transcriptional coactivator YAP1

1

4

High-throughput

0.479

High

821300

TCPE
T-complex protein 1 subunit epsilon

1

1

High-throughput

0.479

High

906012

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

1

High-throughput

0.479

High

1051884

IF4A2
Eukaryotic initiation factor 4A-II

1

1

High-throughput

0.479

High

1139232

KHDR2
KH domain-containing, RNA-binding, signal transduction-associated protein 2

1

1

High-throughput

0.479

High

1174757

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

1

1

High-throughput

0.479

High

1221338

TOPB1
DNA topoisomerase 2-binding protein 1

1

1

High-throughput

0.479

High

1221356

CDK19
Cyclin-dependent kinase 19

1

1

High-throughput

0.479

High

1221363

SFR19
Splicing factor, arginine/serine-rich 19

1

1

High-throughput

0.479

High

1221367

RPA2
DNA-directed RNA polymerase I subunit RPA2

1

3

High-throughput

0.479

High

1221381

RPA12
DNA-directed RNA polymerase I subunit RPA12

1

2

High-throughput

0.479

High

1221382

PHRF1
PHD and RING finger domain-containing protein 1

1

1

High-throughput

0.479

High

1221388

MED13
Mediator of RNA polymerase II transcription subunit 13

1

1

High-throughput

0.479

High

1221394

RPC8
DNA-directed RNA polymerase III subunit RPC8

1

2

High-throughput

0.479

High

179714

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

265344

MED24
Mediator of RNA polymerase II transcription subunit 24

1

0

High-throughput

0.458

High

270202

RPC9
DNA-directed RNA polymerase III subunit RPC9

1

0

High-throughput

0.458

High

270516

MED6
Mediator of RNA polymerase II transcription subunit 6

1

0

High-throughput

0.458

High

272632

OFD1
Centriole and centriolar satellite protein OFD1

1

0

High-throughput

0.458

High

282956

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

0

High-throughput

0.458

High

304638

SCAF4
SR-related and CTD-associated factor 4

1

0

High-throughput

0.458

High

319004

CEP43
Centrosomal protein 43

1

0

High-throughput

0.458

High

319256

BRD1
Bromodomain-containing protein 1

1

0

High-throughput

0.458

High

379592

MYCN
N-myc proto-oncogene protein

1

0

High-throughput

0.458

High

402734

RPC4
DNA-directed RNA polymerase III subunit RPC4

1

0

High-throughput

0.458

High

409155

K2C8
Keratin, type II cytoskeletal 8

1

0

High-throughput

0.458

High

430257

PROF1
Profilin-1

1

0

High-throughput

0.458

High

577770

NELFE
Negative elongation factor E

1

0

High-throughput

0.458

High

720875

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

722010

RFC4
Replication factor C subunit 4

1

0

High-throughput

0.458

High

779713

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

818883

RXRG
Retinoic acid receptor RXR-gamma

1

0

High-throughput

0.458

High

840759

DYN2
Dynamin-2

1

0

High-throughput

0.458

High

891884

ACTB
Actin, cytoplasmic 1

1

0

High-throughput

0.458

High

931263

YBOX1
Y-box-binding protein 1

1

0

High-throughput

0.458

High

964367

RUNX1
Runt-related transcription factor 1

1

0

High-throughput

0.458

High

998873

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

1036719

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

1074712

MED22
Mediator of RNA polymerase II transcription subunit 22

1

0

High-throughput

0.458

High

1081093

CCDC6
Coiled-coil domain-containing protein 6

1

0

High-throughput

0.458

High

1148304

INT3
Integrator complex subunit 3

1

0

High-throughput

0.458

High

1158901

MED27
Mediator of RNA polymerase II transcription subunit 27

1

0

High-throughput

0.458

High

1182924

SPT6H
Transcription elongation factor SPT6

1

0

High-throughput

0.458

High

1192479

CNTRL
Centriolin

1

0

High-throughput

0.458

High

1221332

INT1
Integrator complex subunit 1

1

0

High-throughput

0.458

High

1221333

SIR6
NAD-dependent protein deacylase sirtuin-6

1

0

High-throughput

0.458

High

1221334

CE120
Centrosomal protein of 120 kDa

1

0

High-throughput

0.458

High

1221335

EHBP1
EH domain-binding protein 1

1

0

High-throughput

0.458

High

1221336

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

1221337

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

1

0

High-throughput

0.458

High

1221343

MED8
Mediator of RNA polymerase II transcription subunit 8

1

0

High-throughput

0.458

High

1221345

INT4
Integrator complex subunit 4

1

0

High-throughput

0.458

High

1221350

MED15
Mediator of RNA polymerase II transcription subunit 15

1

0

High-throughput

0.458

High

1221353

MED10
Mediator of RNA polymerase II transcription subunit 10

1

0

High-throughput

0.458

High

1221358

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

1221362

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1221366

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.458

High

1221371

HELLS
Lymphoid-specific helicase

1

0

High-throughput

0.458

High

1221374

INT7
Integrator complex subunit 7

1

0

High-throughput

0.458

High

1221384

ZO2
Tight junction protein ZO-2

1

0

High-throughput

0.458

High

1221385

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1221386

ARMX3
Armadillo repeat-containing X-linked protein 3

1

0

High-throughput

0.458

High

1221387

ZNHI2
Zinc finger HIT domain-containing protein 2

1

0

High-throughput

0.458

High

1221391

MARE3
Microtubule-associated protein RP/EB family member 3

1

0

High-throughput

0.458

High

1221395

TF3C3
General transcription factor 3C polypeptide 3

1

0

High-throughput

0.458

High

112043

ASURF
ASNSD1 upstream open reading frame protein

1

0

High-throughput

0.426

High

875101

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.426

High

1221347

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.426

High

1150671

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

4

0

High-throughput

0.353

High

1173129

SYDE1
Rho GTPase-activating protein SYDE1

2

0

High-throughput

0.328

High

473867

MYZAP
Myocardial zonula adherens protein

2

0

High-throughput

0.313

High

1221348

DAA10
Dynein axonemal assembly factor 10

2

0

High-throughput

0.305

High

245200

RAMP1
Receptor activity-modifying protein 1

1

0

High-throughput

0.279

Low

361697

APOC3
Apolipoprotein C-III

1

0

High-throughput

0.279

Low

957107

TSG6
Tumor necrosis factor-inducible gene 6 protein

1

0

High-throughput

0.279

Low

1221339

F168A
Protein FAM168A

1

0

High-throughput

0.279

Low

100934

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

1138569

LRCH2
Leucine-rich repeat and calponin homology domain-containing protein 2

1

0

High-throughput

0.249

Low

1221378

ASND1
Asparagine synthetase domain-containing protein 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024