HitPredict

Interactor 1: LHX8 (Q68G74)
LIM/homeobox protein Lhx8 (LIM homeobox protein 8)
Gene: LHX8

Interactor 2: SSBP4 (Q9BWG4)
Single-stranded DNA-binding protein 4
Gene: SSBP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26186194, 28514442, 33961781, 35140242
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 356 Hs			1 385
+	Hs
		1148491 LHX8_HUMAN (1-356): 1.97e-83: 259: 100.00		SSBP3_HUMAN (6-385): 7.32e-54: 184: 70.03
+	Hs
		1314660 LHX6_HUMAN (15-344): 3.69e-64: 209: 57.83		SSBP4_HUMAN (1-385): 6e-71: 228: 100.00
+	Hs
		238118 LMX1B_HUMAN (70-354): 1.67e-61: 203: 30.03		SSBP4_HUMAN (1-385): 6e-71: 228: 100.00
+	Hs
		899932 ISL1_HUMAN (62-336): 3.56e-58: 193: 30.10		SSBP4_HUMAN (1-385): 6e-71: 228: 100.00
+	Hs
		1314654 LHX9_HUMAN (66-356): 1.02e-56: 191: 27.00		SSBP4_HUMAN (1-385): 6e-71: 228: 100.00
+	Hs
		822672 LHX1_HUMAN (74-353): 2.82e-56: 190: 25.89		SSBP4_HUMAN (1-385): 6e-71: 228: 100.00
+	Hs
		946646 LHX8_HUMAN (1-356): 1.97e-83: 259: 100.00		SSBP2_HUMAN (1-385): 1.3e-43: 156: 69.51
+	Hs
		1314911 LHX6_HUMAN (15-344): 3.69e-64: 209: 57.83		SSBP3_HUMAN (6-385): 7.32e-54: 184: 70.03
+	Hs
		238119 LMX1B_HUMAN (70-354): 1.67e-61: 203: 30.03		SSBP3_HUMAN (6-385): 7.32e-54: 184: 70.03
+	Mm
		291998 LMX1B_MOUSE (70-347): 4.02e-59: 197: 30.41		Q3U4B1_MOUSE (1-385): 1.89e-54: 185: 83.68
+	Mm
		292011 LMX1B_MOUSE (70-347): 4.02e-59: 197: 30.41		SSBP3_MOUSE (6-385): 7.32e-54: 184: 70.03
+	Hs
		899933 ISL1_HUMAN (62-336): 3.56e-58: 193: 30.10		SSBP3_HUMAN (6-385): 7.32e-54: 184: 70.03
+	Mm
		899944 ISL1_MOUSE (62-336): 3.56e-58: 193: 30.10		SSBP3_MOUSE (6-385): 7.32e-54: 184: 70.03
+	Hs
		1314903 LHX9_HUMAN (66-356): 1.02e-56: 191: 27.00		SSBP3_HUMAN (6-385): 7.32e-54: 184: 70.03
+	Hs
		946674 LHX6_HUMAN (15-344): 3.69e-64: 209: 57.83		SSBP2_HUMAN (1-385): 1.3e-43: 156: 69.51
+	Hs
		238106 LMX1B_HUMAN (70-354): 1.67e-61: 203: 30.03		SSBP2_HUMAN (1-385): 1.3e-43: 156: 69.51
+	Mm
		292010 LMX1B_MOUSE (70-347): 4.02e-59: 197: 30.41		SSBP2_MOUSE (1-385): 5.05e-44: 157: 69.77
+	Mm
		899943 ISL1_MOUSE (62-336): 3.56e-58: 193: 30.10		SSBP2_MOUSE (1-385): 5.05e-44: 157: 69.77
+	Hs
		899917 ISL1_HUMAN (62-336): 3.56e-58: 193: 30.10		SSBP2_HUMAN (1-385): 1.3e-43: 156: 69.51
+	Hs
		822624 LHX1_HUMAN (74-353): 2.82e-56: 190: 25.89		SSBP2_HUMAN (1-385): 1.3e-43: 156: 69.51