Protein: CLC4A
C-type lectin domain family 4 member A (C-type lectin DDB27) (C-type lectin superfamily member 6) (Dendritic cell immunoreceptor) (Lectin-like immunoreceptor) (CD antigen CD367)

Gene: CLC4A, CLEC4A
Organism: Homo sapiens
Interactions: 114
UniProt ID: Q9UMR7

Gene Ontology (top 5):
GO:0001818 - negative regulation of cytokine production
GO:0002250 - adaptive immune response
GO:0002470 - plasmacytoid dendritic cell antigen processing and presentation
GO:0004888 - transmembrane signaling receptor activity
GO:0005509 - calcium ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

564860

NCAM1
Neural cell adhesion molecule 1

2

6

High-throughput

0.776

High

898395

BCAM
Basal cell adhesion molecule

2

11

High-throughput

0.776

High

1232147

VASN
Vasorin

2

12

High-throughput

0.776

High

1380606

IGSF8
Immunoglobulin superfamily member 8

2

6

High-throughput

0.776

High

1462067

PCDBD
Protocadherin beta-13

2

8

High-throughput

0.776

High

1462071

ROBO1
Roundabout homolog 1

2

4

High-throughput

0.776

High

1339798

CADM4
Cell adhesion molecule 4

2

11

High-throughput

0.694

High

276229

LRRN2
Leucine-rich repeat neuronal protein 2

1

17

High-throughput

0.691

High

333535

MPZL1
Myelin protein zero-like protein 1

1

5

High-throughput

0.691

High

521048

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

16

High-throughput

0.691

High

522753

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

6

High-throughput

0.691

High

556421

CADH1
Cadherin-1

1

13

High-throughput

0.691

High

580853

PVR
Poliovirus receptor

1

10

High-throughput

0.691

High

640327

EPHA1
Ephrin type-A receptor 1

1

7

High-throughput

0.691

High

719760

HLAF
HLA class I histocompatibility antigen, alpha chain F

1

16

High-throughput

0.691

High

845859

MUC18
Cell surface glycoprotein MUC18

1

8

High-throughput

0.691

High

932010

EPHB4
Ephrin type-B receptor 4

1

8

High-throughput

0.691

High

1005378

SHPS1
Tyrosine-protein phosphatase non-receptor type substrate 1

1

6

High-throughput

0.691

High

1062197

PCDH1
Protocadherin-1

1

8

High-throughput

0.691

High

1128564

DSC3
Desmocollin-3

1

8

High-throughput

0.691

High

1144686

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

1

7

High-throughput

0.691

High

1177206

MICB
MHC class I polypeptide-related sequence B

1

19

High-throughput

0.691

High

1249992

LRIG3
Leucine-rich repeats and immunoglobulin-like domains protein 3

1

15

High-throughput

0.691

High

1310189

AGRA3
Adhesion G protein-coupled receptor A3

1

13

High-throughput

0.691

High

1366081

PXDN
Peroxidasin homolog

1

11

High-throughput

0.691

High

1366794

NECT2
Nectin-2

1

17

High-throughput

0.691

High

1369602

NEO1
Neogenin

1

5

High-throughput

0.691

High

1390507

LIGO1
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1

1

16

High-throughput

0.691

High

1416523

JAM3
Junctional adhesion molecule C

1

17

High-throughput

0.691

High

1447211

NECT3
Nectin-3

1

10

High-throughput

0.691

High

1454252

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

18

High-throughput

0.691

High

1462061

PCDGK
Protocadherin gamma-C3

1

6

High-throughput

0.691

High

1462068

PCDGB
Protocadherin gamma-A11

1

9

High-throughput

0.691

High

1462069

PCDGA
Protocadherin gamma-A10

1

9

High-throughput

0.691

High

834699

TNFL9
Tumor necrosis factor ligand superfamily member 9

1

0

High-throughput

0.656

High

1309274

IGDC3
Immunoglobulin superfamily DCC subclass member 3

1

9

High-throughput

0.618

High

1454453

FPRP
Prostaglandin F2 receptor negative regulator

1

10

High-throughput

0.618

High

276256

SEM7A
Semaphorin-7A

2

8

High-throughput

0.601

High

648738

FGFR4
Fibroblast growth factor receptor 4

2

11

High-throughput

0.601

High

1034377

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

2

8

High-throughput

0.601

High

1101794

PTK7
Inactive tyrosine-protein kinase 7

2

7

High-throughput

0.601

High

1293313

LSR
Lipolysis-stimulated lipoprotein receptor

2

0

High-throughput

0.576

High

1348248

TIP
T-cell immunomodulatory protein

2

0

High-throughput

0.576

High

409538

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

16

High-throughput

0.575

High

1177253

MICA
MHC class I polypeptide-related sequence A

1

19

High-throughput

0.575

High

1322701

CADM3
Cell adhesion molecule 3

1

10

High-throughput

0.575

High

1462059

PCDB8
Protocadherin beta-8

1

8

High-throughput

0.575

High

1462060

PCDBA
Protocadherin beta-10

1

8

High-throughput

0.575

High

1462064

PCDB5
Protocadherin beta-5

1

8

High-throughput

0.575

High

1462065

PCDB2
Protocadherin beta-2

1

8

High-throughput

0.575

High

1462066

PCDBE
Protocadherin beta-14

1

8

High-throughput

0.575

High

1411257

MXRA8
Matrix remodeling-associated protein 8

1

0

High-throughput

0.546

High

269713

PLXA2
Plexin-A2

1

13

High-throughput

0.536

High

287740

KS6A5
Ribosomal protein S6 kinase alpha-5

1

3

High-throughput

0.536

High

290358

KS6A4
Ribosomal protein S6 kinase alpha-4

1

3

High-throughput

0.536

High

296389

ATRN
Attractin

1

8

High-throughput

0.536

High

541754

FGFR1
Fibroblast growth factor receptor 1

1

12

High-throughput

0.536

High

641282

FGFR2
Fibroblast growth factor receptor 2

1

10

High-throughput

0.536

High

650486

FGFR3
Fibroblast growth factor receptor 3

1

12

High-throughput

0.536

High

655026

ITA6
Integrin alpha-6

1

6

High-throughput

0.536

High

658792

JAK1
Tyrosine-protein kinase JAK1

1

8

High-throughput

0.536

High

661344

AT2B4
Plasma membrane calcium-transporting ATPase 4

1

5

High-throughput

0.536

High

692280

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

1

4

High-throughput

0.536

High

764469

CTNA1
Catenin alpha-1

1

2

High-throughput

0.536

High

777792

VGFR3
Vascular endothelial growth factor receptor 3

1

9

High-throughput

0.536

High

787467

TGFR1
TGF-beta receptor type-1

1

1

High-throughput

0.536

High

1008603

I13R1
Interleukin-13 receptor subunit alpha-1

1

6

High-throughput

0.536

High

1022988

EFNB1
Ephrin-B1

1

1

High-throughput

0.536

High

1034205

ROR1
Inactive tyrosine-protein kinase transmembrane receptor ROR1

1

10

High-throughput

0.536

High

1116983

CD166
CD166 antigen

1

11

High-throughput

0.536

High

1153492

EFNB3
Ephrin-B3

1

1

High-throughput

0.536

High

1159903

OCLN
Occludin

1

2

High-throughput

0.536

High

1162316

AT2B3
Plasma membrane calcium-transporting ATPase 3

1

3

High-throughput

0.536

High

1219098

DAB2P
Disabled homolog 2-interacting protein

1

3

High-throughput

0.536

High

1245151

RHDF2
Inactive rhomboid protein 2

1

1

High-throughput

0.536

High

1325662

FGRL1
Fibroblast growth factor receptor-like 1

1

12

High-throughput

0.536

High

1394693

KIRR1
Kin of IRRE-like protein 1

1

4

High-throughput

0.536

High

1405316

PKP4
Plakophilin-4

1

3

High-throughput

0.536

High

1412080

S39A3
Zinc transporter ZIP3

1

1

High-throughput

0.536

High

1446313

CD320
CD320 antigen

1

4

High-throughput

0.536

High

567785

TF
Tissue factor

1

0

High-throughput

0.513

High

1358416

SCTM1
Secreted and transmembrane protein 1

1

0

High-throughput

0.513

High

1452277

SL2A8
Solute carrier family 2, facilitated glucose transporter member 8

1

0

High-throughput

0.513

High

76161

B4DET5
cDNA FLJ59484, highly similar to Nuclear envelope pore membrane protein POM 121

1

2

High-throughput

0.489

High

684523

CTNA2
Catenin alpha-2

1

2

High-throughput

0.489

High

1191811

VMA21
Vacuolar ATPase assembly integral membrane protein VMA21

1

2

High-throughput

0.489

High

1228380

GL8D1
Glycosyltransferase 8 domain-containing protein 1

1

5

High-throughput

0.489

High

1280089

FRMD5
FERM domain-containing protein 5

1

3

High-throughput

0.489

High

1399792

RBM14
RNA-binding protein 14

1

2

High-throughput

0.489

High

1436651

IPPK
Inositol-pentakisphosphate 2-kinase

1

1

High-throughput

0.489

High

1450637

ARL8B
ADP-ribosylation factor-like protein 8B

1

4

High-throughput

0.489

High

1459707

SUN2
SUN domain-containing protein 2

1

4

High-throughput

0.489

High

1460170

EI2BD
Translation initiation factor eIF2B subunit delta

1

1

High-throughput

0.489

High

1462062

DJC16
DnaJ homolog subfamily C member 16

1

7

High-throughput

0.489

High

1462063

TBL2
Transducin beta-like protein 2

1

3

High-throughput

0.489

High

607673

PTN2
Tyrosine-protein phosphatase non-receptor type 2

1

14

High-throughput

0.445

High

1236162

TEN4
Teneurin-4

1

12

High-throughput

0.445

High

1449505

TEN2
Teneurin-2

1

11

High-throughput

0.445

High

1454332

TEN3
Teneurin-3

1

12

High-throughput

0.445

High

386361

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

6

High-throughput

0.439

High

814888

CUX1
Homeobox protein cut-like 1

1

5

High-throughput

0.437

High

1119465

CASP
Protein CASP

1

13

High-throughput

0.407

High

65319

RFOX3
RNA binding protein fox-1 homolog 3

1

0

High-throughput

0.279

Low

71365

F1712
Protein FAM171A2

1

0

High-throughput

0.279

Low

223666

NDUB5
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial

1

0

High-throughput

0.279

Low

397775

NU6M
NADH-ubiquinone oxidoreductase chain 6

1

0

High-throughput

0.279

Low

665156

COT2
COUP transcription factor 2

1

0

High-throughput

0.279

Low

1095960

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

0

High-throughput

0.279

Low

1224788

RN213
E3 ubiquitin-protein ligase RNF213

1

0

High-throughput

0.279

Low

1251571

THADA
tRNA

1

0

High-throughput

0.279

Low

1392729

ZCCHL
Zinc finger CCCH-type antiviral protein 1-like

1

0

High-throughput

0.279

Low

1449393

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

1

0

High-throughput

0.279

Low

1462070

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

0

High-throughput

0.279

Low

852685

PPIC
Peptidyl-prolyl cis-trans isomerase C

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025