HitPredict

Interactor 1: KCD11 (Q693B1)
BTB/POZ domain-containing protein KCTD11 (KCASH1 protein) (Potassium channel tetramerization domain-containing protein 11) (RING-type E3 ubiquitin transferase subunit KCTD11)
Gene: KCTD11

Interactor 2: KCD11 (Q693B1)
BTB/POZ domain-containing protein KCTD11 (KCASH1 protein) (Potassium channel tetramerization domain-containing protein 11) (RING-type E3 ubiquitin transferase subunit KCTD11)
Gene: KCTD11

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.839

Property	Details
Experiments	21237243, 27152988, 21472142
Identification Methods	affinity chromatography technology, molecular sieving, electron microscopy, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	BTB_2~BTB_2
Common GO terms	GO:0007049 - cell cycle GO:0016567 - protein ubiquitination GO:0016740 - transferase activity GO:0045666 - positive regulation of neuron differentiation GO:0051260 - protein homooligomerization
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 232 Hs			1 232
+	Hs
		1116786 KCD11_HUMAN (1-232): 7.53e-86: 255: 100.00		KCD21_HUMAN (1-232): 3.99e-78: 237: 38.08
+	Hs
		1116784 KCD21_HUMAN (1-232): 3.99e-78: 237: 38.08		KCD21_HUMAN (1-232): 3.99e-78: 237: 38.08
+	Hs
		1116797 KCD21_HUMAN (1-232): 3.99e-78: 237: 38.08		KCD15_HUMAN (2-214): 7.3e-50: 166: 21.13
+	Hs
		1148532 KCD11_HUMAN (1-232): 7.53e-86: 255: 100.00		KCTD6_HUMAN (1-78): 2.69e-27: 106: 50.00
+	Hs
		1116791 KCD21_HUMAN (1-232): 3.99e-78: 237: 38.08		KCTD6_HUMAN (1-78): 2.69e-27: 106: 50.00
+	Hs
		1302202 KCD15_HUMAN (2-214): 7.3e-50: 166: 21.13		KCD15_HUMAN (2-214): 7.3e-50: 166: 21.13
+	Hs
		1348070 KCTD5_HUMAN (9-174): 1.06e-50: 166: 16.27		KCTD5_HUMAN (9-174): 1.06e-50: 166: 16.27
+	Hs
		1057245 KCTD5_HUMAN (9-174): 1.06e-50: 166: 16.27		KCTD2_HUMAN (9-174): 3.09e-48: 161: 17.47
+	Hs
		1057220 KCTD2_HUMAN (9-174): 3.09e-48: 161: 17.47		KCTD2_HUMAN (9-174): 3.09e-48: 161: 17.47
+	Hs
		1174581 KCD15_HUMAN (2-214): 7.3e-50: 166: 21.13		KCTD1_HUMAN (2-214): 5.33e-46: 155: 21.60
+	Hs
		1235381 KCTD5_HUMAN (9-174): 1.06e-50: 166: 16.27		KCD17_HUMAN (13-165): 2.01e-43: 150: 19.61
+	Hs
		1057229 KCTD2_HUMAN (9-174): 3.09e-48: 161: 17.47		KCD17_HUMAN (13-165): 2.01e-43: 150: 19.61
+	Hs
		1174571 KCTD1_HUMAN (2-214): 5.33e-46: 155: 21.60		KCTD1_HUMAN (2-214): 5.33e-46: 155: 21.60
+	Ce
		1090431 Q18986_CAEEL (1-207): 9.28e-46: 154: 24.11		Q18986_CAEEL (1-207): 9.28e-46: 154: 24.11
+	Dm
		89870 TIWAZ_DROME (2-190): 1.21e-43: 152: 23.08		TIWAZ_DROME (2-190): 1.21e-43: 152: 23.08
+	Hs
		1089457 KCD15_HUMAN (2-214): 7.3e-50: 166: 21.13		KCD19_HUMAN (21-86): 5.09e-20: 90.2: 42.42