HitPredict

Interactor 1: KCD11 (Q693B1)
BTB/POZ domain-containing protein KCTD11 (KCASH1 protein) (Potassium channel tetramerization domain-containing protein 11) (RING-type E3 ubiquitin transferase subunit KCTD11)
Gene: KCTD11

Interactor 2: KCTD6 (Q8NC69)
BTB/POZ domain-containing protein KCTD6 (KCASH3 protein) (Potassium channel tetramerization domain-containing protein 6)
Gene: KCTD6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	33961781, 21472142
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	BTB_2~BTB_2
Common GO terms	GO:0016567 - protein ubiquitination GO:0051260 - protein homooligomerization
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 232 Hs			1 237
+	Hs
		1116791 KCD21_HUMAN (1-232): 3.99e-78: 237: 38.08		KCTD6_HUMAN (1-237): 3.1e-83: 249: 100.00
+	Hs
		1116797 KCD21_HUMAN (1-232): 3.99e-78: 237: 38.08		KCD15_HUMAN (10-234): 4.86e-53: 174: 29.24
+	Hs
		1116786 KCD11_HUMAN (1-232): 7.53e-86: 255: 100.00		KCD21_HUMAN (10-157): 4.44e-43: 147: 49.33
+	Hs
		1116784 KCD21_HUMAN (1-232): 3.99e-78: 237: 38.08		KCD21_HUMAN (10-157): 4.44e-43: 147: 49.33
+	Hs
		1348073 KCTD5_HUMAN (9-174): 1.06e-50: 166: 16.27		KCND2_HUMAN (7-210): 2.88e-62: 206: 19.90
+	Hs
		1057246 KCTD2_HUMAN (9-174): 3.09e-48: 161: 17.47		KCND2_HUMAN (7-210): 2.88e-62: 206: 19.90
+	Hs
		1302202 KCD15_HUMAN (2-214): 7.3e-50: 166: 21.13		KCD15_HUMAN (10-234): 4.86e-53: 174: 29.24
+	Hs
		1174581 KCD15_HUMAN (2-214): 7.3e-50: 166: 21.13		KCTD1_HUMAN (10-235): 6.1e-51: 167: 28.69
+	Hs
		1148530 KCD11_HUMAN (1-232): 7.53e-86: 255: 100.00		KCD11_HUMAN (37-107): 1.34e-16: 77.8: 54.67
+	Hs
		1348070 KCTD5_HUMAN (9-174): 1.06e-50: 166: 16.27		KCTD5_HUMAN (8-197): 8.63e-49: 161: 26.80
+	Hs
		1057245 KCTD5_HUMAN (9-174): 1.06e-50: 166: 16.27		KCTD2_HUMAN (6-197): 9.14e-48: 160: 23.35
+	Hs
		1235381 KCTD5_HUMAN (9-174): 1.06e-50: 166: 16.27		KCD17_HUMAN (12-191): 2.51e-46: 157: 28.96
+	Hs
		1174571 KCTD1_HUMAN (2-214): 5.33e-46: 155: 21.60		KCTD1_HUMAN (10-235): 6.1e-51: 167: 28.69
+	Hs
		1057220 KCTD2_HUMAN (9-174): 3.09e-48: 161: 17.47		KCTD2_HUMAN (6-197): 9.14e-48: 160: 23.35
+	Hs
		1057229 KCTD2_HUMAN (9-174): 3.09e-48: 161: 17.47		KCD17_HUMAN (12-191): 2.51e-46: 157: 28.96
+	Hs
		1302211 KCD15_HUMAN (2-214): 7.3e-50: 166: 21.13		KCTD3_HUMAN (10-156): 1.77e-37: 140: 32.65
+	Hs
		1089457 KCD15_HUMAN (2-214): 7.3e-50: 166: 21.13		KCD19_HUMAN (2-196): 8.78e-17: 80.9: 19.81