HitPredict

Interactor 1: WWC2 (Q6AWC2)
Protein WWC2 (BH-3-only member B) (WW domain-containing protein 2)
Gene: WWC2

Interactor 2: LATS2 (Q9NRM7)
Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)
Gene: LATS2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24682284
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1192 Hs			1 1088
+	Hs
		1344970 WWC3_HUMAN (6-1192): 0: 836: 43.32		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		1220087 KIBRA_HUMAN (1-1192): 0: 810: 49.04		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		325775 WWC2_HUMAN (1-1192): 0: 1008: 100.00		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325937 WWC3_HUMAN (6-1192): 0: 836: 43.32		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325797 KIBRA_HUMAN (1-1192): 0: 810: 49.04		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		1300675 MAGI1_HUMAN (1-300): 2.32e-62: 236: 18.94		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Dm
		1360813 KIBRA_DROME (8-1190): 0: 661: 30.31		WARTS_DROME (167-1039): 7.21e-137: 443: 39.71
+	Hs
		1330812 SAV1_HUMAN (4-88): 3.52e-27: 117: 38.82		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		325859 MAGI1_HUMAN (1-300): 2.32e-62: 236: 18.94		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325914 WWOX_HUMAN (5-198): 5.51e-47: 176: 21.11		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325886 WWP1_HUMAN (6-136): 2.07e-35: 148: 23.78		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325772 MAGI3_HUMAN (9-97): 1.18e-34: 146: 43.82		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325853 ITCH_HUMAN (7-143): 1.17e-33: 142: 24.66		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		125071 WWP2_HUMAN (3-143): 4.17e-30: 131: 23.84		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325888 SAV1_HUMAN (4-88): 3.52e-27: 117: 38.82		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		1073444 MAGI2_HUMAN (2-686): 1.34e-94: 334: 14.59		KS6A1_HUMAN (519-977): 1.47e-79: 277: 20.34
+	Ce
		88187 D3YT29_CAEEL (77-277): 8.17e-41: 165: 18.66		WARTS_CAEEL (393-1050): 8.43e-135: 432: 35.98
+	Hs
		568765 ITCH_HUMAN (7-143): 1.17e-33: 142: 24.66		KAPCA_HUMAN (635-1024): 1.31e-133: 410: 31.73
+	Hs
		1073470 MAGI1_HUMAN (1-300): 2.32e-62: 236: 18.94		KS6A1_HUMAN (519-977): 1.47e-79: 277: 20.34
+	Hs
		1073434 MAGI3_HUMAN (9-97): 1.18e-34: 146: 43.82		KS6A1_HUMAN (519-977): 1.47e-79: 277: 20.34