HitPredict

Interactor 1: MRCKG (Q6DT37)
Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) (DMPK-like gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (MRCK gamma) (MRCKG) (Myotonic dystrophy protein kinase-like gamma) (Myotonic dystrophy protein kinase-like alpha)
Gene: CDC42BPG

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1551 Hs			1 530
+	Hs
		1270038 MRCKB_HUMAN (2-1529): 0: 1261: 41.72		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		370819 MRCKB_HUMAN (2-1529): 0: 1261: 41.72		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369789 MRCKA_HUMAN (2-1539): 0: 1257: 43.49		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		487519 MRCKG_HUMAN (1-1551): 0: 1461: 100.00		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		659748 MRCKB_HUMAN (2-1529): 0: 1261: 41.72		RXRB_HUMAN (96-498): 2.03e-108: 335: 27.05
+	Hs
		487504 MRCKA_HUMAN (2-1539): 0: 1257: 43.49		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		1233527 MINK1_HUMAN (47-1344): 0: 620: 15.64		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369994 MINK1_HUMAN (47-1344): 0: 620: 15.64		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		647937 MARK3_HUMAN (17-767): 2.1e-154: 490: 16.23		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		149132 CTRO_HUMAN (11-871): 6.09e-129: 446: 26.03		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369024 MARK3_HUMAN (17-767): 2.1e-154: 490: 16.23		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		1269904 TAOK2_HUMAN (45-885): 3.21e-129: 435: 16.32		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		148263 CTRO_HUMAN (11-871): 6.09e-129: 446: 26.03		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370685 TAOK2_HUMAN (45-885): 3.21e-129: 435: 16.32		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		368941 KAPCA_HUMAN (43-371): 1.08e-128: 406: 33.14		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		568575 KAPCA_HUMAN (43-371): 1.08e-128: 406: 33.14		HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30
+	Hs
		369645 STK38_HUMAN (60-398): 1.93e-88: 298: 42.93		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		487788 LATS2_HUMAN (59-371): 4.47e-66: 247: 39.34		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59