Protein: UBC9
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (mUBC9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I)

Gene: UBC9, Ube2i
Organism: Mus musculus
Interactions: 54
UniProt ID: P63280

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001221 - transcription coregulator binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005643 - nuclear pore

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

854773

RAGP1
Ran GTPase-activating protein 1

4

8

Small-scale

0.885

High

991473

SUMO1
Small ubiquitin-related modifier 1

2

19

Small-scale

0.767

High

236337

PIAS3
E3 SUMO-protein ligase PIAS3

1

14

Small-scale

0.713

High

148770

NF2IP
NFATC2-interacting protein

1

1

Small-scale

0.710

High

509020

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

1

20

High-throughput

0.647

High

662960

MDM2
E3 ubiquitin-protein ligase Mdm2

1

15

Small-scale

0.647

High

993863

SUMO3
Small ubiquitin-related modifier 3

1

19

Small-scale

0.647

High

586094

TFE2
Transcription factor E2-alpha

3

2

Small-scale

0.637

High

993860

XPO7
Exportin-7

1

3

High-throughput

0.575

High

993844

NR2C1
Nuclear receptor subfamily 2 group C member 1

1

8

Small-scale

0.573

High

993845

UIMC1
BRCA1-A complex subunit RAP80

1

1

Small-scale

0.573

High

466726

EGR2
E3 SUMO-protein ligase EGR2

1

3

Small-scale

0.552

High

583141

IRF1
Interferon regulatory factor 1

1

4

Small-scale

0.549

High

941626

CTBP2
C-terminal-binding protein 2

1

4

Small-scale

0.527

High

675220

TNR6
Tumor necrosis factor receptor superfamily member 6

2

2

Small-scale

0.526

High

772438

CALX
Calnexin

1

3

Small-scale

0.504

High

607330

GATA1
Erythroid transcription factor

1

1

Small-scale

0.501

High

629223

PO5F1
POU domain, class 5, transcription factor 1

1

6

Small-scale

0.501

High

872967

SOX2
Transcription factor SOX-2

1

9

Small-scale

0.501

High

941886

TDG
G/T mismatch-specific thymine DNA glycosylase

1

1

Small-scale

0.501

High

993847

HIF1A
Hypoxia-inducible factor 1-alpha

1

2

Small-scale

0.501

High

993862

C8AP2
CASP8-associated protein 2

1

1

Small-scale

0.501

High

312341

FOXL2
Forkhead box protein L2

1

2

Small-scale

0.481

High

530956

THIO
Thioredoxin

1

2

High-throughput

0.481

High

660946

IRF8
Interferon regulatory factor 8

1

4

Small-scale

0.481

High

663327

IRF2
Interferon regulatory factor 2

1

4

Small-scale

0.481

High

953230

ACTB
Actin, cytoplasmic 1

1

4

High-throughput

0.481

High

972200

1433E
14-3-3 protein epsilon

1

1

High-throughput

0.481

High

993841

RL22
Large ribosomal subunit protein eL22

1

1

High-throughput

0.481

High

993846

GRB2
Growth factor receptor-bound protein 2

1

1

High-throughput

0.481

High

993848

TSN
Translin

1

3

High-throughput

0.481

High

993852

Q8BQ46
TAF15 RNA polymerase II, TATA box binding protein

1

1

High-throughput

0.481

High

993853

GNL3
Guanine nucleotide-binding protein-like 3

1

2

High-throughput

0.481

High

993854

PSPC1
Paraspeckle component 1

1

6

High-throughput

0.481

High

993855

DX39A
ATP-dependent RNA helicase DDX39A

1

11

High-throughput

0.481

High

993856

TADBP
TAR DNA-binding protein 43

1

7

High-throughput

0.481

High

993857

NONO
Non-POU domain-containing octamer-binding protein

1

6

High-throughput

0.481

High

993861

SPAG6
Sperm-associated antigen 6

1

1

High-throughput

0.481

High

993864

ILF3
Interleukin enhancer-binding factor 3

1

7

High-throughput

0.481

High

993865

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

8

High-throughput

0.481

High

993858

MTHFS
5-formyltetrahydrofolate cyclo-ligase

1

0

Small-scale

0.480

High

147754

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

2

High-throughput

0.479

High

205169

FYB1
FYN-binding protein 1

1

5

Small-scale

0.479

High

876521

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C]

1

8

Small-scale

0.479

High

927691

ATX1
Ataxin-1

1

4

High-throughput

0.479

High

993843

SKAP1
Src kinase-associated phosphoprotein 1

1

3

Small-scale

0.479

High

993859

BI2L1
BAR/IMD domain-containing adapter protein 2-like 1

1

1

Small-scale

0.479

High

991793

DYL1
Dynein light chain 1, cytoplasmic

1

0

High-throughput

0.460

High

148460

IKZF3
Zinc finger protein Aiolos

1

7

Small-scale

0.457

High

993842

IKZF1
DNA-binding protein Ikaros

1

7

Small-scale

0.457

High

993851

Q8BK32
Nuclear receptor co-repressor 1

1

2

Small-scale

0.439

High

648040

MYD88
Myeloid differentiation primary response protein MyD88

1

0

High-throughput

0.438

High

993850

NEMP1
Nuclear envelope integral membrane protein 1

1

1

Small-scale

0.417

High

993849

ZC11A
Zinc finger CCCH domain-containing protein 11A

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025