HitPredict

Interactor 1: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Interactor 2: PCBP2 (Q15366)
Poly(rC)-binding protein 2 (Alpha-CP2) (Heterogeneous nuclear ribonucleoprotein E2) (hnRNP E2)
Gene: PCBP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21723381
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 494 Hs			1 365
+	Hs
		516531 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		PCBP2_HUMAN (1-365): 6.73e-117: 345: 100.00
+	Mm
		904278 SRSF1_MOUSE (3-166): 2.36e-57: 192: 41.42		HNRPK_MOUSE (10-361): 2.75e-76: 244: 26.17
+	Mm
		192620 SRSF5_MOUSE (3-175): 9.86e-54: 183: 64.57		HNRPK_MOUSE (10-361): 2.75e-76: 244: 26.17
+	Mm
		904251 SRSF6_MOUSE (1-200): 5.39e-48: 170: 74.76		HNRPK_MOUSE (10-361): 2.75e-76: 244: 26.17
+	Hs
		516439 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		HNRPK_HUMAN (10-361): 2.75e-76: 244: 26.17
+	Mm
		665747 PABP1_MOUSE (1-189): 6.69e-31: 128: 19.50		HNRPK_MOUSE (10-361): 2.75e-76: 244: 26.17
+	Mm
		904294 RBM4_MOUSE (1-218): 3.79e-19: 90.8: 23.85		HNRPK_MOUSE (10-361): 2.75e-76: 244: 26.17
+	Hs
		1028924 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		PCBP1_HUMAN (93-173): 3.7e-12: 68.7: 28.40
+	Hs
		1028764 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		FUBP1_HUMAN (216-362): 1.11e-13: 74.1: 19.73
+	Hs
		516642 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		FUBP3_HUMAN (244-362): 8.21e-15: 77.6: 22.69
+	Hs
		516530 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		PCBP1_HUMAN (93-173): 3.7e-12: 68.7: 28.40
+	Mm
		1111896 RBM4_MOUSE (1-218): 3.79e-19: 90.8: 23.85		Q3TIX6_MOUSE (244-362): 1.03e-14: 77.2: 22.69
+	Mm
		1130843 RBM4_MOUSE (1-218): 3.79e-19: 90.8: 23.85		IF2B2_MOUSE (15-185): 4.61e-13: 72.4: 33.71
+	Hs
		963557 TIAR_HUMAN (96-188): 2.66e-10: 63.8: 16.67		FUBP2_HUMAN (282-364): 1.14e-16: 83.3: 30.12
+	Hs
		1031431 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		FUBP3_HUMAN (244-362): 8.21e-15: 77.6: 22.69
+	Hs
		1031417 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		FUBP1_HUMAN (216-362): 1.11e-13: 74.1: 19.73
+	Hs
		963561 TIAR_HUMAN (96-188): 2.66e-10: 63.8: 16.67		FUBP3_HUMAN (244-362): 8.21e-15: 77.6: 22.69
+	Hs
		680479 TIA1_HUMAN (98-188): 6.06e-10: 63.1: 17.02		FUBP3_HUMAN (244-362): 8.21e-15: 77.6: 22.69
+	Hs
		963559 TIAR_HUMAN (96-188): 2.66e-10: 63.8: 16.67		FUBP1_HUMAN (216-362): 1.11e-13: 74.1: 19.73
+	Sc
		376757 PABP_YEAST (72-188): 2.61e-10: 64.6: 14.75		PBP2_YEAST (64-255): 1.66e-11: 67.2: 14.80