HitPredict

Interactor 1: RGPA1 (Q6GYQ0)
Ral GTPase-activating protein subunit alpha-1 (GAP-related-interacting partner to E12) (GRIPE) (GTPase-activating Rap/Ran-GAP domain-like 1) (Tuberin-like protein 1) (p240)
Gene: RALGAPA1

Interactor 2: RND1 (Q92730)
Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1)
Gene: RND1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Rap_GAP~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2036 Hs			1 232
+	Hs
		901183 RGPA1_HUMAN (1-2036): 0: 2954: 100.00		RND3_HUMAN (1-232): 1.75e-100: 293: 58.20
+	Hs
		894131 RGPA1_HUMAN (1-2036): 0: 2954: 100.00		CDC42_HUMAN (11-197): 1.18e-80: 241: 37.43
+	Hs
		925359 RGPA1_HUMAN (1-2036): 0: 2954: 100.00		RAC1_HUMAN (11-200): 6.76e-80: 239: 38.42
+	Hs
		892432 RGPA1_HUMAN (1-2036): 0: 2954: 100.00		RAC3_HUMAN (11-188): 5.54e-77: 232: 39.89
+	Hs
		914140 RGPA1_HUMAN (1-2036): 0: 2954: 100.00		RB11A_HUMAN (1-231): 1.91e-76: 231: 18.88
+	Hs
		900583 RGPA1_HUMAN (1-2036): 0: 2954: 100.00		RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94
+	Hs
		951081 RGPA1_HUMAN (1-2036): 0: 2954: 100.00		RHOG_HUMAN (11-198): 1.56e-76: 230: 37.77
+	Hs
		915756 RGPA1_HUMAN (1-2036): 0: 2954: 100.00		RHOB_HUMAN (13-190): 2.91e-49: 161: 44.94
+	Hs
		120494 RGPA1_HUMAN (1-2036): 0: 2954: 100.00		RHOD_HUMAN (6-189): 1.79e-48: 160: 40.76
+	Hs
		914099 RGPA2_HUMAN (1-2030): 0: 2671: 49.46		RB11A_HUMAN (1-231): 1.91e-76: 231: 18.88
+	Hs
		951036 RGPA2_HUMAN (1-2030): 0: 2671: 49.46		RHOG_HUMAN (11-198): 1.56e-76: 230: 37.77
+	Hs
		915714 RGPA2_HUMAN (1-2030): 0: 2671: 49.46		RHOB_HUMAN (13-190): 2.91e-49: 161: 44.94
+	Hs
		925514 SIPA1_HUMAN (1603-2018): 1.13e-117: 402: 16.91		RAC1_HUMAN (11-200): 6.76e-80: 239: 38.42
+	Hs
		900790 SIPA1_HUMAN (1603-2018): 1.13e-117: 402: 16.91		RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94
+	Hs
		894180 RLGPB_HUMAN (1126-1884): 1.5e-105: 375: 16.67		CDC42_HUMAN (11-197): 1.18e-80: 241: 37.43
+	Hs
		852540 RLGPB_HUMAN (1126-1884): 1.5e-105: 375: 16.67		RND2_HUMAN (12-232): 9.62e-80: 240: 53.15
+	Hs
		892464 RLGPB_HUMAN (1126-1884): 1.5e-105: 375: 16.67		RAC3_HUMAN (11-188): 5.54e-77: 232: 39.89
+	Hs
		196428 SI1L1_HUMAN (1683-2015): 2.28e-106: 380: 19.22		RHOB_HUMAN (13-190): 2.91e-49: 161: 44.94
+	Hs
		916041 SI1L2_HUMAN (1694-2016): 4.06e-106: 379: 18.88		RHOB_HUMAN (13-190): 2.91e-49: 161: 44.94
+	Hs
		120517 RLGPB_HUMAN (1126-1884): 1.5e-105: 375: 16.67		RHOD_HUMAN (6-189): 1.79e-48: 160: 40.76