Interactor 1: H2KYI8 (H2KYI8)
DH domain-containing protein
Gene: cgef-1

Interactor 2: RHEB1 (P34443)
GTP-binding protein Rheb homolog 1 (EC 3.6.5.-)
Gene: rheb-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.50 0.80 0.637

The method score is based on:

Property Details
Experiments 29515755
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ras~RhoGEF, Ras~SOS1_NGEF_PH
Common GO terms -
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 464
Ce

1 207
+ Hs
+ Mm
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025