HitPredict

Interactor 1: KLH10 (Q6JEL2)
Kelch-like protein 10
Gene: KLHL10

Interactor 2: CSN3 (Q9UNS2)
COP9 signalosome complex subunit 3 (SGN3) (Signalosome subunit 3) (JAB1-containing signalosome subunit 3)
Gene: COPS3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 608 Hs			1 423
+	Hs
		1120829 KLH12_HUMAN (19-575): 8.8e-171: 499: 32.32		CSN3_HUMAN (1-423): 2.33e-144: 419: 100.00
+	Hs
		1350341 KLHL8_HUMAN (5-574): 1.07e-158: 470: 28.37		CSN3_HUMAN (1-423): 2.33e-144: 419: 100.00
+	Hs
		897257 KLH12_HUMAN (19-575): 8.8e-171: 499: 32.32		CSN2_HUMAN (21-393): 1.28e-87: 275: 12.23
+	Hs
		897321 KLHL8_HUMAN (5-574): 1.07e-158: 470: 28.37		CSN2_HUMAN (21-393): 1.28e-87: 275: 12.23
+	Hs
		1120807 KLH12_HUMAN (19-575): 8.8e-171: 499: 32.32		CSN4_HUMAN (1-397): 3.04e-62: 208: 15.87
+	Hs
		1350484 KLH13_HUMAN (387-607): 5.12e-53: 194: 21.93		CSN3_HUMAN (1-423): 2.33e-144: 419: 100.00
+	Hs
		299535 KLH18_HUMAN (461-608): 2.26e-35: 142: 27.33		CSN3_HUMAN (1-423): 2.33e-144: 419: 100.00
+	Hs
		897322 KLH13_HUMAN (387-607): 5.12e-53: 194: 21.93		CSN2_HUMAN (21-393): 1.28e-87: 275: 12.23
+	Dm
		1249187 Q9VK21_DROME (338-578): 1.23e-23: 107: 29.76		CSN3_DROME (1-423): 2.7e-116: 348: 50.79
+	Hs
		897262 KLH10_HUMAN (435-608): 1.37e-42: 163: 22.29		CSN2_HUMAN (21-393): 1.28e-87: 275: 12.23
+	Hs
		299512 KLH18_HUMAN (461-608): 2.26e-35: 142: 27.33		CSN2_HUMAN (21-393): 1.28e-87: 275: 12.23
+	Hs
		1311911 KLH13_HUMAN (387-607): 5.12e-53: 194: 21.93		CSN4_HUMAN (1-397): 3.04e-62: 208: 15.87
+	Hs
		897264 KLH24_HUMAN (448-607): 1.58e-21: 100: 18.56		CSN2_HUMAN (21-393): 1.28e-87: 275: 12.23
+	Hs
		1153792 KLH10_HUMAN (435-608): 1.37e-42: 163: 22.29		CSN4_HUMAN (1-397): 3.04e-62: 208: 15.87
+	Hs
		299532 KLH18_HUMAN (461-608): 2.26e-35: 142: 27.33		CSN4_HUMAN (1-397): 3.04e-62: 208: 15.87