HitPredict - High confidence protein-protein interactions

Interactor 1: IFIX (Q6K0P9)
Pyrin and HIN domain-containing protein 1 (Interferon-inducible protein X)
Gene: PYHIN1

Interactor 2: IFIX (Q6K0P9)
Pyrin and HIN domain-containing protein 1 (Interferon-inducible protein X)
Gene: PYHIN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	28077445, 25665578
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HIN~HIN, PYRIN~PYRIN
Common GO terms	GO:0002218 - activation of innate immune response GO:0003690 - double-stranded DNA binding GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005829 - cytosol and 13 others more... GO:0007049 - cell cycle GO:0016607 - nuclear speck GO:0031625 - ubiquitin protein ligase binding GO:0031648 - protein destabilization GO:0032991 - protein-containing complex GO:0035457 - cellular response to interferon-alpha GO:0035458 - cellular response to interferon-beta GO:0043388 - positive regulation of DNA binding GO:0045893 - positive regulation of DNA-templated transcription GO:0050821 - protein stabilization GO:1900182 - positive regulation of protein localization to nucleus GO:1902164 - positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:2000060 - positive regulation of ubiquitin-dependent protein catabolic process
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	492
Hs

1	492

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024