Interactor 1: SCN9A (Q15858)
Sodium channel protein type 9 subunit alpha (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1) (PN1) (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7)
Gene: SCN9A

Interactor 2: SCN2A (Q99250)
Sodium channel protein type 2 subunit alpha (HBSC II) (Sodium channel protein brain II subunit alpha) (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2)
Gene: SCN2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 36950384
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ion_trans~Ion_trans
Common GO terms GO:0001518 - voltage-gated sodium channel complex
GO:0005248 - voltage-gated sodium channel activity
GO:0005886 - plasma membrane
GO:0019228 - neuronal action potential
GO:0030424 - axon
and 3 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1988
Hs

1 2005
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025