Protein: SCN4A
Sodium channel protein type 4 subunit alpha (SkM1) (Sodium channel protein skeletal muscle subunit alpha) (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4)

Gene: SCN4A
Organism: Homo sapiens
Interactions: 93
UniProt ID: P35499

Gene Ontology (top 5):
GO:0001518 - voltage-gated sodium channel complex
GO:0005248 - voltage-gated sodium channel activity
GO:0005886 - plasma membrane
GO:0006814 - sodium ion transport
GO:0006936 - muscle contraction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

771828

SCN8A
Sodium channel protein type 8 subunit alpha

1

5

High-throughput

0.691

High

771765

SCN1B
Sodium channel regulatory subunit beta-1

1

3

Small-scale

0.666

High

222358

TSN6
Tetraspanin-6

1

3

High-throughput

0.536

High

247504

FZD6
Frizzled-6

1

4

High-throughput

0.536

High

321748

AGRL1
Adhesion G protein-coupled receptor L1

1

8

High-throughput

0.536

High

336528

PIGN
GPI ethanolamine phosphate transferase 1

1

1

High-throughput

0.536

High

349387

TSN15
Tetraspanin-15

1

3

High-throughput

0.536

High

560956

GP1BB
Platelet glycoprotein Ib beta chain

1

4

High-throughput

0.536

High

603858

CXA1
Gap junction alpha-1 protein

1

1

High-throughput

0.536

High

771759

AGRE5
Adhesion G protein-coupled receptor E5

1

11

High-throughput

0.536

High

771770

FZD2
Frizzled-2

1

4

High-throughput

0.536

High

771771

ICAM4
Intercellular adhesion molecule 4

1

1

High-throughput

0.536

High

771772

SLMAP
Sarcolemmal membrane-associated protein

1

9

High-throughput

0.536

High

771786

AGRG6
Adhesion G-protein coupled receptor G6

1

8

High-throughput

0.536

High

771802

CTL1
Choline transporter-like protein 1

1

1

High-throughput

0.536

High

771806

DNJC1
DnaJ homolog subfamily C member 1

1

5

High-throughput

0.536

High

771811

SMO
Protein smoothened

1

4

High-throughput

0.536

High

771815

S1PR5
Sphingosine 1-phosphate receptor 5

1

5

High-throughput

0.536

High

771816

FZD8
Frizzled-8

1

4

High-throughput

0.536

High

771769

SNTA1
Alpha-1-syntrophin

1

12

Small-scale

0.527

High

328808

CSPG5
Chondroitin sulfate proteoglycan 5

1

0

High-throughput

0.513

High

771758

GLRB
Glycine receptor subunit beta

1

0

High-throughput

0.513

High

771760

MFAP3
Microfibril-associated glycoprotein 3

1

0

High-throughput

0.513

High

771776

TM63B
Mechanosensitive cation channel TMEM63B

1

0

High-throughput

0.513

High

771778

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.513

High

771780

MFS12
Major facilitator superfamily domain-containing protein 12

1

0

High-throughput

0.513

High

771789

TM219
Insulin-like growth factor-binding protein 3 receptor

1

0

High-throughput

0.513

High

771794

S15A4
Solute carrier family 15 member 4

1

0

High-throughput

0.513

High

771796

GOLM1
Golgi membrane protein 1

1

0

High-throughput

0.513

High

771797

SIDT2
SID1 transmembrane family member 2

1

0

High-throughput

0.513

High

771799

SPP2B
Signal peptide peptidase-like 2B

1

0

High-throughput

0.513

High

771810

S29A1
Equilibrative nucleoside transporter 1

1

0

High-throughput

0.513

High

771812

SELS
Selenoprotein S

1

0

High-throughput

0.513

High

771814

YIPF3
Protein YIPF3

1

0

High-throughput

0.513

High

771817

PIGU
GPI-anchor transamidase component PIGU

1

0

High-throughput

0.513

High

771823

CNNM1
Metal transporter CNNM1

1

0

High-throughput

0.513

High

771827

NB5R1
NADH-cytochrome b5 reductase 1

1

0

High-throughput

0.513

High

771808

ERBIN
Erbin

1

0

Small-scale

0.505

High

274288

SIN3B
Paired amphipathic helix protein Sin3b

1

1

High-throughput

0.489

High

611013

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

10

High-throughput

0.489

High

771779

MYORG
Myogenesis-regulating glycosidase

1

1

High-throughput

0.489

High

771782

XIRP1
Xin actin-binding repeat-containing protein 1

1

1

High-throughput

0.489

High

771783

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

1

High-throughput

0.489

High

771787

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

2

High-throughput

0.489

High

771788

CARM1
Histone-arginine methyltransferase CARM1

1

2

High-throughput

0.489

High

771792

MACOI
Macoilin

1

9

High-throughput

0.489

High

771800

PIGO
GPI ethanolamine phosphate transferase 3, catalytic subunit

1

1

High-throughput

0.489

High

771807

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

4

High-throughput

0.489

High

771829

DJC16
DnaJ homolog subfamily C member 16

1

5

High-throughput

0.489

High

595327

H15
Histone H1.5

1

1

High-throughput

0.470

High

771762

RL10A
Large ribosomal subunit protein uL1

1

2

High-throughput

0.470

High

771764

H11
Histone H1.1

1

1

High-throughput

0.470

High

771768

DNJC3
DnaJ homolog subfamily C member 3

1

1

High-throughput

0.470

High

437107

K2C8
Keratin, type II cytoskeletal 8

1

4

High-throughput

0.437

High

506569

GPHRB
Golgi pH regulator B

1

1

High-throughput

0.437

High

732250

PRDX2
Peroxiredoxin-2

1

1

High-throughput

0.437

High

85346

GPHRA
Golgi pH regulator A

1

1

High-throughput

0.407

High

771805

NEUL4
Neuralized-like protein 4

1

2

High-throughput

0.407

High

162797

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

1

5

Small-scale

0.373

High

66787

C2C4B
C2 calcium-dependent domain-containing protein 4B

1

0

High-throughput

0.279

Low

212553

GPAA1
GPI-anchor transamidase component GPAA1

1

0

High-throughput

0.279

Low

253817

TPST2
Protein-tyrosine sulfotransferase 2

1

0

High-throughput

0.279

Low

771757

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.279

Low

771761

SELT
Thioredoxin reductase-like selenoprotein T

1

0

High-throughput

0.279

Low

771763

EREP3
Protein ENTREP3

1

0

High-throughput

0.279

Low

771766

MGT5A
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

1

0

High-throughput

0.279

Low

771767

TMM62
Transmembrane protein 62

1

0

High-throughput

0.279

Low

771773

CGT
2-hydroxyacylsphingosine 1-beta-galactosyltransferase

1

0

High-throughput

0.279

Low

771774

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.279

Low

771775

PPM1L
Protein phosphatase 1L

1

0

High-throughput

0.279

Low

771777

DIK1A
Divergent protein kinase domain 1A

1

0

High-throughput

0.279

Low

771781

TMPPE
Transmembrane protein with metallophosphoesterase domain

1

0

High-throughput

0.279

Low

771784

D19L4
Probable C-mannosyltransferase DPY19L4

1

0

High-throughput

0.279

Low

771785

PIGW
Glucosaminyl-phosphatidylinositol-acyltransferase PIGW

1

0

High-throughput

0.279

Low

771790

PLD6
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.279

Low

771791

GLT16
Polypeptide N-acetylgalactosaminyltransferase 16

1

0

High-throughput

0.279

Low

771793

PAR16
Protein mono-ADP-ribosyltransferase PARP16

1

0

High-throughput

0.279

Low

771795

FITM2
Acyl-coenzyme A diphosphatase FITM2

1

0

High-throughput

0.279

Low

771798

UXS1
UDP-glucuronic acid decarboxylase 1

1

0

High-throughput

0.279

Low

771801

NAT14
Probable N-acetyltransferase 14

1

0

High-throughput

0.279

Low

771803

F162A
Protein FAM162A

1

0

High-throughput

0.279

Low

771804

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

771809

SEC62
Translocation protein SEC62

1

0

High-throughput

0.279

Low

771813

ALG12
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase

1

0

High-throughput

0.279

Low

771818

SG196
Protein O-mannose kinase

1

0

High-throughput

0.279

Low

771819

S38AA
Solute carrier family 38 member 10

1

0

High-throughput

0.279

Low

771820

EMC7
Endoplasmic reticulum membrane protein complex subunit 7

1

0

High-throughput

0.279

Low

771821

CHSTB
Carbohydrate sulfotransferase 11

1

0

High-throughput

0.279

Low

771822

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.279

Low

771824

PLCD
1-acyl-sn-glycerol-3-phosphate acyltransferase delta

1

0

High-throughput

0.279

Low

771825

EMC3
ER membrane protein complex subunit 3

1

0

High-throughput

0.279

Low

771826

B4GT7
Beta-1,4-galactosyltransferase 7

1

0

High-throughput

0.279

Low

610549

TCPA
T-complex protein 1 subunit alpha

1

0

High-throughput

0.269

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025