HitPredict

Interactor 1: VPS72 (Q15906)
Vacuolar protein sorting-associated protein 72 homolog (Protein YL-1) (Transcription factor-like 1)
Gene: VPS72

Interactor 2: H2B1A (Q96A08)
Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B)
Gene: H2BC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	1.00	0.892

Property	Details
Experiments	26186194, 28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~YL1
Common GO terms	GO:0000786 - nucleosome GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0042393 - histone binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 364 Hs			1 127
+	Hs
		1155292 VPS72_HUMAN (1-364): 3.23e-143: 412: 100.00		H2B2E_HUMAN (1-127): 4.41e-54: 167: 85.83
+	Hs
		1155313 VPS72_HUMAN (1-364): 3.23e-143: 412: 100.00		H2B1H_HUMAN (5-127): 5.54e-54: 166: 85.37
+	Hs
		256867 VPS72_HUMAN (1-364): 3.23e-143: 412: 100.00		H2B1K_HUMAN (1-127): 8.59e-54: 166: 84.25
+	Hs
		980793 VPS72_HUMAN (1-364): 3.23e-143: 412: 100.00		H2B1C_HUMAN (1-127): 8.23e-54: 166: 85.04
+	Hs
		1155303 VPS72_HUMAN (1-364): 3.23e-143: 412: 100.00		H2B3B_HUMAN (1-127): 9.02e-51: 158: 85.83
+	Sc
		381612 VPS72_YEAST (3-201): 3.08e-31: 127: 20.47		H2B2_YEAST (4-126): 4.48e-41: 134: 69.36