Protein: H2B3B
Histone H2B type 3-B (H2B type 12) (H2B-clustered histone 26) (H2B.U histone 1)

Gene: H2B3B, H2BC26
Organism: Homo sapiens
Interactions: 183
UniProt ID: Q8N257

Gene Ontology (top 5):
GO:0000786 - nucleosome
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1323968

H2B1L
Histone H2B type 1-L

4

19

High-throughput

0.886

High

502432

H2A1
Histone H2A type 1

3

20

High-throughput

0.847

High

256924

H2B1K
Histone H2B type 1-K

3

20

High-throughput

0.827

High

419081

H2A1B
Histone H2A type 1-B/E

3

20

High-throughput

0.827

High

1065298

SSRP1
FACT complex subunit SSRP1

2

20

High-throughput

0.811

High

888184

MCM2
DNA replication licensing factor MCM2

2

20

High-throughput

0.789

High

1109889

HDAC1
Histone deacetylase 1

2

20

Small-scale

0.789

High

1162831

H2A2C
Histone H2A type 2-C

2

20

High-throughput

0.789

High

1163052

H2B2E
Histone H2B type 2-E

2

20

High-throughput

0.789

High

1307273

H2A2B
Histone H2A type 2-B

2

20

High-throughput

0.789

High

1323959

IPO9
Importin-9

2

15

High-throughput

0.789

High

946831

H2B1D
Histone H2B type 1-D

2

20

High-throughput

0.754

High

979974

H4
Histone H4

2

20

High-throughput

0.754

High

980922

H2B1C
Histone H2B type 1-C/E/F/G/I

2

20

High-throughput

0.754

High

998535

H31
Histone H3.1

2

20

Small-scale

0.754

High

1232695

H2A2A
Histone H2A type 2-A

2

20

High-throughput

0.754

High

277742

H2AY
Core histone macro-H2A.1

1

20

High-throughput

0.691

High

455823

H10
Histone H1.0

1

3

High-throughput

0.691

High

502052

H2AZ
Histone H2A.Z

1

20

High-throughput

0.691

High

649361

H1T
Histone H1t

1

20

High-throughput

0.691

High

936805

NP1L1
Nucleosome assembly protein 1-like 1

1

19

High-throughput

0.691

High

1028278

MDM2
E3 ubiquitin-protein ligase Mdm2

1

4

High-throughput

0.691

High

1155303

VPS72
Vacuolar protein sorting-associated protein 72 homolog

1

7

High-throughput

0.691

High

1253851

SRCAP
Helicase SRCAP

1

20

High-throughput

0.691

High

1323942

BAHD1
Bromo adjacent homology domain-containing 1 protein

1

7

High-throughput

0.691

High

1323945

HDAC2
Histone deacetylase 2

1

20

High-throughput

0.691

High

1323946

KAT5
Histone acetyltransferase KAT5

1

20

High-throughput

0.691

High

1323957

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

10

High-throughput

0.691

High

1323958

EP400
E1A-binding protein p400

1

20

High-throughput

0.691

High

1323963

NP1L4
Nucleosome assembly protein 1-like 4

1

20

High-throughput

0.691

High

1323977

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

4

High-throughput

0.691

High

1323994

H2AW
Core histone macro-H2A.2

1

20

High-throughput

0.691

High

1324001

CDYL
Chromodomain Y-like protein

1

10

High-throughput

0.691

High

1324006

SP16H
FACT complex subunit SPT16

1

8

High-throughput

0.691

High

187136

PPM1G
Protein phosphatase 1G

3

11

High-throughput

0.667

High

853342

CBX5
Chromobox protein homolog 5

1

20

Small-scale

0.647

High

449752

H2B1J
Histone H2B type 1-J

1

20

High-throughput

0.618

High

507273

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

20

High-throughput

0.618

High

508268

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

20

High-throughput

0.618

High

521804

H14
Histone H1.4

1

20

High-throughput

0.618

High

591730

H2AX
Histone H2AX

1

20

High-throughput

0.618

High

595510

H15
Histone H1.5

1

20

Small-scale

0.618

High

634045

H2A1D
Histone H2A type 1-D

1

20

High-throughput

0.618

High

651380

CBL
E3 ubiquitin-protein ligase CBL

1

20

High-throughput

0.618

High

659915

H2B1O
Histone H2B type 1-O

1

20

High-throughput

0.618

High

754909

H2B1B
Histone H2B type 1-B

1

20

High-throughput

0.618

High

883607

CENPA
Histone H3-like centromeric protein A

1

20

Small-scale

0.618

High

943391

H2BFS
Histone H2B type F-S

1

19

High-throughput

0.618

High

987107

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

20

High-throughput

0.618

High

987408

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

20

High-throughput

0.618

High

1017017

H33
Histone H3.3

1

20

High-throughput

0.618

High

1197640

MIDN
Midnolin

1

1

High-throughput

0.618

High

1208854

H2B2F
Histone H2B type 2-F

1

20

High-throughput

0.618

High

1272804

H2A3
Histone H2A type 3

1

20

High-throughput

0.618

High

1323949

H2A1C
Histone H2A type 1-C

1

20

High-throughput

0.618

High

1323950

H2B1H
Histone H2B type 1-H

1

19

High-throughput

0.618

High

1323956

H2A1H
Histone H2A type 1-H

1

20

High-throughput

0.618

High

1323960

H2A1A
Histone H2A type 1-A

1

20

High-throughput

0.618

High

1323962

RING2
E3 ubiquitin-protein ligase RING2

1

20

High-throughput

0.618

High

1323965

H2B1N
Histone H2B type 1-N

1

19

High-throughput

0.618

High

1323966

H2A1J
Histone H2A type 1-J

1

20

High-throughput

0.618

High

1323967

H2B1M
Histone H2B type 1-M

1

19

High-throughput

0.618

High

1323971

H2AJ
Histone H2A.J

1

20

High-throughput

0.618

High

1323989

RAD18
E3 ubiquitin-protein ligase RAD18

1

1

High-throughput

0.618

High

1324004

TRRAP
Transformation/transcription domain-associated protein

2

7

High-throughput

0.611

High

1194212

LARP7
La-related protein 7

2

20

High-throughput

0.584

High

842802

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

10

Small-scale

0.561

High

211653

ZNHI1
Zinc finger HIT domain-containing protein 1

1

2

High-throughput

0.536

High

317346

ACL6B
Actin-like protein 6B

1

10

High-throughput

0.536

High

340362

YETS4
YEATS domain-containing protein 4

1

10

High-throughput

0.536

High

355248

ACL6A
Actin-like protein 6A

1

9

High-throughput

0.536

High

487521

PARP1
Poly [ADP-ribose] polymerase 1

1

20

High-throughput

0.536

High

586780

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.536

High

594046

NCK1
SH2/SH3 adapter protein NCK1

1

11

High-throughput

0.536

High

892593

DNLI3
DNA ligase 3

1

4

High-throughput

0.536

High

1032837

XPC
DNA repair protein complementing XP-C cells

1

6

High-throughput

0.536

High

1043706

CEBPZ
CCAAT/enhancer-binding protein zeta

1

3

High-throughput

0.536

High

1053300

MBTD1
MBT domain-containing protein 1

1

17

High-throughput

0.536

High

1124117

NPAT
Protein NPAT

1

1

High-throughput

0.536

High

1130939

BMS1
Ribosome biogenesis protein BMS1 homolog

1

6

High-throughput

0.536

High

1133262

ARI5B
AT-rich interactive domain-containing protein 5B

1

19

High-throughput

0.536

High

1134642

NUMA1
Nuclear mitotic apparatus protein 1

1

20

High-throughput

0.536

High

1137853

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.536

High

1187975

GON4L
GON-4-like protein

1

3

High-throughput

0.536

High

1198101

EPC2
Enhancer of polycomb homolog 2

1

8

High-throughput

0.536

High

1206723

RRP12
RRP12-like protein

1

3

High-throughput

0.536

High

1241392

MED27
Mediator of RNA polymerase II transcription subunit 27

1

1

High-throughput

0.536

High

1250732

MPRIP
Myosin phosphatase Rho-interacting protein

1

13

High-throughput

0.536

High

1253820

MMS22
Protein MMS22-like

1

3

High-throughput

0.536

High

1277266

MIER3
Mesoderm induction early response protein 3

1

13

High-throughput

0.536

High

1322533

MIER1
Mesoderm induction early response protein 1

1

13

High-throughput

0.536

High

1323941

NECP1
Adaptin ear-binding coat-associated protein 1

1

1

High-throughput

0.536

High

1323943

TRI41
E3 ubiquitin-protein ligase TRIM41

1

4

High-throughput

0.536

High

1323944

SRS12
Serine/arginine-rich splicing factor 12

1

8

High-throughput

0.536

High

1323954

TONSL
Tonsoku-like protein

1

11

High-throughput

0.536

High

1323961

CRML
Protein cramped-like

1

2

High-throughput

0.536

High

1323972

AN32E
Acidic leucine-rich nuclear phosphoprotein 32 family member E

1

8

High-throughput

0.536

High

1323978

ARP6
Actin-related protein 6

1

9

High-throughput

0.536

High

1323979

BRD8
Bromodomain-containing protein 8

1

20

High-throughput

0.536

High

1323980

EPC1
Enhancer of polycomb homolog 1

1

8

High-throughput

0.536

High

1323982

CCD86
Coiled-coil domain-containing protein 86

1

3

High-throughput

0.536

High

1323984

EAF6
Chromatin modification-related protein MEAF6

1

4

High-throughput

0.536

High

1323985

DMAP1
DNA methyltransferase 1-associated protein 1

1

4

High-throughput

0.536

High

1323992

TEX10
Testis-expressed protein 10

1

2

High-throughput

0.536

High

1323993

ING3
Inhibitor of growth protein 3

1

16

High-throughput

0.536

High

1323996

PARP2
Poly [ADP-ribose] polymerase 2

1

17

High-throughput

0.536

High

1324002

RUVB1
RuvB-like 1

1

15

High-throughput

0.536

High

1324005

RBM19
Probable RNA-binding protein 19

1

11

High-throughput

0.536

High

482158

RET1
Retinol-binding protein 1

1

0

High-throughput

0.513

High

1323970

HAUS8
HAUS augmin-like complex subunit 8

1

0

High-throughput

0.513

High

1323973

TIPIN
TIMELESS-interacting protein

1

0

High-throughput

0.513

High

1323999

TIM
Protein timeless homolog

1

0

High-throughput

0.513

High

1323947

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

17

Small-scale

0.501

High

244891

LZTS3
Leucine zipper putative tumor suppressor 3

1

19

High-throughput

0.489

High

348161

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

20

High-throughput

0.489

High

1244434

CP087
UPF0547 protein C16orf87

1

2

High-throughput

0.489

High

1323939

KRI1
Protein KRI1 homolog

1

1

High-throughput

0.489

High

1323995

CFDP1
Craniofacial development protein 1

1

5

High-throughput

0.489

High

1323997

S18L2
SS18-like protein 2

1

3

High-throughput

0.489

High

137463

HMGN4
High mobility group nucleosome-binding domain-containing protein 4

1

20

High-throughput

0.479

High

157603

CTRO
Citron Rho-interacting kinase

1

17

High-throughput

0.479

High

223172

PRC1
Protein regulator of cytokinesis 1

1

9

High-throughput

0.479

High

227613

SPOP
Speckle-type POZ protein

1

2

High-throughput

0.479

High

260175

BRD4
Bromodomain-containing protein 4

1

20

High-throughput

0.479

High

319901

UFL1
E3 UFM1-protein ligase 1

1

3

High-throughput

0.479

High

324982

HEXI1
Protein HEXIM1

1

14

High-throughput

0.479

High

331137

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

426533

HMGN2
Non-histone chromosomal protein HMG-17

1

20

High-throughput

0.479

High

571679

HCLS1
Hematopoietic lineage cell-specific protein

1

20

High-throughput

0.479

High

601766

HMGA1
High mobility group protein HMG-I/HMG-Y

1

15

High-throughput

0.479

High

606913

CEBPB
CCAAT/enhancer-binding protein beta

1

3

High-throughput

0.479

High

660672

IF4B
Eukaryotic translation initiation factor 4B

1

13

High-throughput

0.479

High

728333

AKT1
RAC-alpha serine/threonine-protein kinase

1

20

High-throughput

0.479

High

728606

AKT2
RAC-beta serine/threonine-protein kinase

1

20

High-throughput

0.479

High

755979

MCM5
DNA replication licensing factor MCM5

1

20

High-throughput

0.479

High

858983

RL27A
Large ribosomal subunit protein uL15

1

2

High-throughput

0.479

High

859356

RL5
Large ribosomal subunit protein uL18

1

3

Small-scale

0.479

High

861220

MAP1B
Microtubule-associated protein 1B

1

20

High-throughput

0.479

High

983882

RBX1
E3 ubiquitin-protein ligase RBX1

1

2

High-throughput

0.479

High

1004366

NOP14
Nucleolar protein 14

1

4

High-throughput

0.479

High

1008797

RED1
Double-stranded RNA-specific editase 1

1

14

High-throughput

0.479

High

1095275

REST
RE1-silencing transcription factor

1

7

High-throughput

0.479

High

1140547

KIF14
Kinesin-like protein KIF14

1

16

High-throughput

0.479

High

1151423

HMGN3
High mobility group nucleosome-binding domain-containing protein 3

1

14

High-throughput

0.479

High

1211602

TEX35
Testis-expressed protein 35

1

12

High-throughput

0.479

High

1218564

MYSM1
Deubiquitinase MYSM1

1

20

Small-scale

0.479

High

1226776

AR6P4
ADP-ribosylation factor-like protein 6-interacting protein 4

1

3

High-throughput

0.479

High

1271732

MEPCE
7SK snRNA methylphosphate capping enzyme

1

14

High-throughput

0.479

High

1280333

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

8

Small-scale

0.479

High

1281371

DPPA2
Developmental pluripotency-associated protein 2

1

10

High-throughput

0.479

High

1323940

SERB1
SERPINE1 mRNA-binding protein 1

1

12

High-throughput

0.479

High

1323951

CHM4C
Charged multivesicular body protein 4c

1

9

High-throughput

0.479

High

1323953

SPDLY
Protein Spindly

1

18

High-throughput

0.479

High

1323969

VRK1
Serine/threonine-protein kinase VRK1

1

6

High-throughput

0.479

High

1323974

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

20

High-throughput

0.479

High

1323975

FACD2
Fanconi anemia group D2 protein

1

9

High-throughput

0.479

High

1323976

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

3

High-throughput

0.479

High

1323986

BRD7
Bromodomain-containing protein 7

1

20

Small-scale

0.479

High

1323987

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

2

Small-scale

0.479

High

1323988

DUOX2
Dual oxidase 2

1

12

High-throughput

0.479

High

1323991

PIHD1
PIH1 domain-containing protein 1

1

2

High-throughput

0.479

High

322426

HAUS5
HAUS augmin-like complex subunit 5

1

0

High-throughput

0.458

High

1228547

HAUS3
HAUS augmin-like complex subunit 3

1

0

High-throughput

0.458

High

1278408

HAUS6
HAUS augmin-like complex subunit 6

1

0

High-throughput

0.458

High

1323952

HAUS1
HAUS augmin-like complex subunit 1

1

0

High-throughput

0.458

High

1323964

HAUS7
HAUS augmin-like complex subunit 7

1

0

High-throughput

0.458

High

1323981

HAUS4
HAUS augmin-like complex subunit 4

1

0

High-throughput

0.458

High

1323990

HAUS2
HAUS augmin-like complex subunit 2

1

0

High-throughput

0.458

High

530071

TAU
Microtubule-associated protein tau

1

20

High-throughput

0.445

High

1102314

CD5R2
Cyclin-dependent kinase 5 activator 2

1

12

High-throughput

0.437

High

1247548

ZN474
Zinc finger protein 474

1

10

High-throughput

0.437

High

1254611

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.437

High

1308357

CCD71
Coiled-coil domain-containing protein 71

1

3

Small-scale

0.437

High

1313732

MILK2
MICAL-like protein 2

1

7

High-throughput

0.437

High

1323938

RHG24
Rho GTPase-activating protein 24

1

15

High-throughput

0.437

High

1323948

SBP2L
Selenocysteine insertion sequence-binding protein 2-like

1

4

High-throughput

0.437

High

1323955

DDRGK
DDRGK domain-containing protein 1

1

2

High-throughput

0.437

High

1323998

HECD1
E3 ubiquitin-protein ligase HECTD1

1

9

High-throughput

0.437

High

1324000

TENN
Tenascin-N

1

20

High-throughput

0.437

High

1324007

PCLO
Protein piccolo

1

20

High-throughput

0.437

High

1323983

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.426

High

87506

OSCRI
SCRIB overlapping open reading frame protein

1

1

High-throughput

0.407

High

1324003

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025