HitPredict

Interactor 1: Q6NSM0 (Q6NSM0)
NR1D2 protein (Nuclear receptor subfamily 1 group D member 2)
Gene: NR1D2

Interactor 2: TRIM1 (Q9UJV3)
Probable E3 ubiquitin-protein ligase MID2 (EC 2.3.2.27) (Midin-2) (Midline defect 2) (Midline-2) (RING finger protein 60) (RING-type E3 ubiquitin transferase MID2) (Tripartite motif-containing protein 1)
Gene: MID2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.59	0.60	0.596

Property	Details
Experiments	25416956, 31515488
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 408 Hs			1 735
+	Hs
		1061371 NR1D2_HUMAN (1-382): 6.65e-144: 423: 100.00		TRIM1_HUMAN (1-735): 0: 592: 100.00
+	Hs
		175702 ESR2_HUMAN (4-277): 2.49e-53: 187: 22.83		TRI18_HUMAN (21-717): 8.76e-175: 518: 72.60
+	Hs
		1061357 NR1D2_HUMAN (1-382): 6.65e-144: 423: 100.00		TRI63_HUMAN (19-400): 2.79e-84: 272: 23.71
+	Hs
		1061367 NR1D2_HUMAN (1-382): 6.65e-144: 423: 100.00		TRI55_HUMAN (20-400): 1.31e-79: 266: 23.26
+	Hs
		536883 Q6NSM0_HUMAN (1-408): 7.96e-158: 452: 100.00		TRI27_HUMAN (16-340): 1.18e-23: 107: 14.15
+	Hs
		369597 ESR1_HUMAN (4-277): 9.37e-66: 221: 20.91		TRI25_HUMAN (24-706): 9.41e-99: 319: 20.96
+	Hs
		536836 NR1D2_HUMAN (1-382): 6.65e-144: 423: 100.00		TRI27_HUMAN (16-340): 1.18e-23: 107: 14.15
+	Hs
		992438 PPARA_HUMAN (8-244): 6.01e-60: 203: 29.75		TRI63_HUMAN (19-400): 2.79e-84: 272: 23.71
+	Hs
		992448 PPARA_HUMAN (8-244): 6.01e-60: 203: 29.75		TRI55_HUMAN (20-400): 1.31e-79: 266: 23.26
+	Hs
		370719 ESR1_HUMAN (4-277): 9.37e-66: 221: 20.91		TRI33_HUMAN (29-581): 5.65e-69: 247: 14.34
+	Hs
		500441 THA_HUMAN (46-293): 9.03e-56: 193: 29.72		TRI63_HUMAN (19-400): 2.79e-84: 272: 23.71
+	Hs
		740576 PPARG_HUMAN (9-277): 1.65e-54: 189: 30.44		TRI63_HUMAN (19-400): 2.79e-84: 272: 23.71
+	Hs
		740594 PPARG_HUMAN (9-277): 1.65e-54: 189: 30.44		TRI55_HUMAN (20-400): 1.31e-79: 266: 23.26
+	Hs
		824357 NR2C2_HUMAN (30-287): 3.09e-53: 188: 22.10		TRI55_HUMAN (20-400): 1.31e-79: 266: 23.26
+	Hs
		370380 ESR1_HUMAN (4-277): 9.37e-66: 221: 20.91		TRIM8_HUMAN (16-417): 5.14e-61: 216: 20.34
+	Hs
		370187 ESR1_HUMAN (4-277): 9.37e-66: 221: 20.91		TRI11_HUMAN (16-269): 1.65e-24: 109: 16.54
+	Hs
		368914 ESR1_HUMAN (4-277): 9.37e-66: 221: 20.91		TRI27_HUMAN (16-340): 1.18e-23: 107: 14.15
+	Hs
		536747 PPARG_HUMAN (9-277): 1.65e-54: 189: 30.44		TRI27_HUMAN (16-340): 1.18e-23: 107: 14.15
+	Hs
		536957 ESR2_HUMAN (4-277): 2.49e-53: 187: 22.83		TRI27_HUMAN (16-340): 1.18e-23: 107: 14.15
+	Hs
		242818 PPARG_HUMAN (9-277): 1.65e-54: 189: 30.44		TRI13_HUMAN (21-117): 1.69e-14: 78.2: 41.24