HitPredict

Interactor 1: ESRP1 (Q6NXG1)
Epithelial splicing regulatory protein 1 (RNA-binding motif protein 35A) (RNA-binding protein 35A)
Gene: ESRP1

Interactor 2: ATX2 (Q99700)
Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein)
Gene: ATXN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003729 - mRNA binding GO:1990904 - ribonucleoprotein complex
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 681 Hs			1 1313
+	Hs
		516661 PABP1_HUMAN (33-318): 5.39e-31: 130: 11.43		ATX2_HUMAN (1-1313): 1.72e-116: 397: 100.00
+	Hs
		1031438 PABP4_HUMAN (25-223): 5.23e-11: 67.8: 9.18		ATX2_HUMAN (1-1313): 1.72e-116: 397: 100.00
+	At
		983453 PABP5_ARATH (221-679): 2.69e-44: 170: 10.98		CID4_ARATH (266-785): 6.27e-34: 141: 17.46
+	Dm
		597063 PABP_DROME (31-325): 8e-31: 130: 10.77		ATX2_DROME (258-1224): 1.25e-36: 152: 19.68
+	Sc
		376873 PABP_YEAST (33-324): 1.77e-30: 128: 8.72		PBP1_YEAST (299-661): 2.63e-35: 146: 21.11
+	At
		1277466 PABP8_ARATH (31-335): 5.89e-31: 130: 10.88		CID4_ARATH (266-785): 6.27e-34: 141: 17.46
+	At
		790113 PABP2_ARATH (31-330): 1.29e-29: 126: 13.15		CID4_ARATH (266-785): 6.27e-34: 141: 17.46
+	At
		248502 PABP3_ARATH (31-309): 9.2e-29: 123: 10.49		CID4_ARATH (266-785): 6.27e-34: 141: 17.46
+	Hs
		516606 PABP1_HUMAN (33-318): 5.39e-31: 130: 11.43		ATX2L_HUMAN (521-1304): 2.92e-19: 96.4: 18.02
+	Hs
		682945 HNRH1_HUMAN (69-298): 1.51e-31: 130: 18.64		CIC_HUMAN (3-783): 2.62e-10: 67.5: 10.47
+	Hs
		516595 PABP1_HUMAN (33-318): 5.39e-31: 130: 11.43		KMT2C_HUMAN (54-860): 6.28e-10: 66.3: 9.19
+	Hs
		878714 HNRH2_HUMAN (69-298): 5.26e-30: 125: 18.22		CIC_HUMAN (3-783): 2.62e-10: 67.5: 10.47
+	Hs
		1031402 PABP4_HUMAN (25-223): 5.23e-11: 67.8: 9.18		ATX2L_HUMAN (521-1304): 2.92e-19: 96.4: 18.02
+	Hs
		855180 HNRPF_HUMAN (438-532): 1.29e-19: 93.8: 35.79		CIC_HUMAN (3-783): 2.62e-10: 67.5: 10.47
+	Hs
		582417 NUCL_HUMAN (232-520): 5.27e-13: 74.5: 17.59		PRG4_HUMAN (47-781): 1.82e-09: 64.6: 8.71
+	Dm
		1366083 Q9VGH5_DROME (328-402): 1.8e-11: 69.1: 33.33		Q9VLS7_DROME (1-695): 1.23e-10: 68.6: 8.91