Protein: KCNA4
Potassium voltage-gated channel subfamily A member 4 (HPCN2) (Voltage-gated K(+) channel HuKII) (Voltage-gated potassium channel HBK4) (Voltage-gated potassium channel HK1) (Voltage-gated potassium channel subunit Kv1.4)

Gene: KCNA4
Organism: Homo sapiens
Interactions: 60
UniProt ID: P22459

Gene Ontology (top 5):
GO:0001508 - action potential
GO:0005249 - voltage-gated potassium channel activity
GO:0005251 - delayed rectifier potassium channel activity
GO:0005886 - plasma membrane
GO:0006813 - potassium ion transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

648770

KCAB2
Voltage-gated potassium channel subunit beta-2

2

13

Small-scale

0.789

High

648766

DLG4
Disks large homolog 4

9

20

Small-scale

0.757

High

648769

DLG1
Disks large homolog 1

6

20

Small-scale

0.727

High

648763

ACTN2
Alpha-actinin-2

1

4

Small-scale

0.713

High

595031

KCNA2
Potassium voltage-gated channel subfamily A member 2

1

15

Small-scale

0.618

High

642618

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

15

Small-scale

0.618

High

648762

KCNA5
Potassium voltage-gated channel subfamily A member 5

1

14

Small-scale

0.618

High

648768

KCNA1
Potassium voltage-gated channel subfamily A member 1

1

14

Small-scale

0.618

High

648784

KCNRG
Potassium channel regulatory protein

1

15

Small-scale

0.618

High

648792

ERBIN
Erbin

2

10

Small-scale

0.613

High

648788

LNX1
E3 ubiquitin-protein ligase LNX

2

20

Small-scale

0.554

High

168634

CSKP
Peripheral plasma membrane protein CASK

1

20

High-throughput

0.536

High

230752

EXTL3
Exostosin-like 3

1

1

High-throughput

0.536

High

262363

DTNB
Dystrobrevin beta

1

4

High-throughput

0.536

High

315118

RECQ4
ATP-dependent DNA helicase Q4

1

3

High-throughput

0.536

High

332868

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

8

High-throughput

0.536

High

547410

DMD
Dystrophin

1

8

High-throughput

0.536

High

648764

UTRN
Utrophin

1

8

High-throughput

0.536

High

648767

EM55
55 kDa erythrocyte membrane protein

1

20

High-throughput

0.536

High

648773

SNTB2
Beta-2-syntrophin

1

20

High-throughput

0.536

High

648774

SNTB1
Beta-1-syntrophin

1

20

High-throughput

0.536

High

648775

SCRIB
Protein scribble homolog

1

20

High-throughput

0.536

High

648777

MPP7
MAGUK p55 subfamily member 7

1

20

High-throughput

0.536

High

648778

ZN746
Zinc finger protein 746

1

1

High-throughput

0.536

High

648779

CC033
Protein C3orf33

1

1

High-throughput

0.536

High

648780

CHSS1
Chondroitin sulfate synthase 1

1

1

High-throughput

0.536

High

648786

GOLM1
Golgi membrane protein 1

1

4

High-throughput

0.536

High

648789

DLG3
Disks large homolog 3

1

20

High-throughput

0.536

High

648794

KC1G1
Casein kinase I isoform gamma-1

1

2

High-throughput

0.536

High

648798

VAPA
Vesicle-associated membrane protein-associated protein A

1

8

High-throughput

0.536

High

648799

CTNL1
Alpha-catulin

1

4

High-throughput

0.536

High

648802

DTNA
Dystrobrevin alpha

1

4

High-throughput

0.536

High

648805

KC1G3
Casein kinase I isoform gamma-3

1

2

High-throughput

0.536

High

648783

UNC5B
Netrin receptor UNC5B

1

2

High-throughput

0.515

High

648771

PLD1
Phospholipase D1

1

0

High-throughput

0.513

High

648804

PCDG3
Protocadherin gamma-A3

1

0

High-throughput

0.513

High

648793

NEUR1
Sialidase-1

1

1

Small-scale

0.501

High

648795

NUA4L
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2

1

1

High-throughput

0.494

High

271898

OBSL1
Obscurin-like protein 1

1

1

High-throughput

0.489

High

648765

KC1E
Casein kinase I isoform epsilon

1

2

High-throughput

0.489

High

648791

P121A
Nuclear envelope pore membrane protein POM 121

1

7

High-throughput

0.489

High

648796

SALL1
Sal-like protein 1

1

1

High-throughput

0.489

High

648800

ZN282
Zinc finger protein 282

1

1

High-throughput

0.489

High

648801

INT6
Integrator complex subunit 6

1

1

High-throughput

0.489

High

440366

FYN
Tyrosine-protein kinase Fyn

1

9

Small-scale

0.479

High

557093

SRC
Proto-oncogene tyrosine-protein kinase Src

1

9

Small-scale

0.479

High

648776

DLG2
Disks large homolog 2

1

20

Small-scale

0.479

High

648790

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

1

Small-scale

0.437

High

648772

SNTA1
Alpha-1-syntrophin

1

20

Small-scale

0.408

High

639581

SAT1
Diamine acetyltransferase 1

3

0

High-throughput

0.348

High

134238

RPOM
DNA-directed RNA polymerase, mitochondrial

1

0

High-throughput

0.279

Low

510026

ZN865
Zinc finger protein 865

1

0

High-throughput

0.279

Low

601950

ZNF8
Zinc finger protein 8

1

0

High-throughput

0.279

Low

617077

ATF1
Cyclic AMP-dependent transcription factor ATF-1

1

0

High-throughput

0.279

Low

648781

GLT12
Polypeptide N-acetylgalactosaminyltransferase 12

1

0

High-throughput

0.279

Low

648782

ZN101
Zinc finger protein 101

1

0

High-throughput

0.279

Low

648785

ZN655
Zinc finger protein 655

1

0

High-throughput

0.279

Low

648787

CC112
Coiled-coil domain-containing protein 112

1

0

High-throughput

0.279

Low

648803

ZSC21
Zinc finger and SCAN domain-containing protein 21

1

0

High-throughput

0.279

Low

648797

ZF64B
Zinc finger protein 64

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025