HitPredict

Interactor 1: PPR18 (Q6NYC8)
Phostensin (Protein phosphatase 1 F-actin cytoskeleton-targeting subunit) (Protein phosphatase 1 regulatory subunit 18)
Gene: PPP1R18

Interactor 2: TSC1 (Q92574)
Hamartin (Tuberous sclerosis 1 protein)
Gene: TSC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 613 Hs			1 1164
+	Hs
		1157415 PPR18_HUMAN (1-613): 8.33e-74: 249: 100.00		Q86WV8_HUMAN (1-343): 3.4e-177: 526: 100.00
+	Hs
		1157430 PPR18_HUMAN (1-613): 8.33e-74: 249: 100.00		MY18A_HUMAN (461-1064): 4e-25: 115: 10.31
+	Hs
		148947 PPR18_HUMAN (1-613): 8.33e-74: 249: 100.00		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		148941 NIPBL_HUMAN (25-436): 9.52e-61: 221: 17.78		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		1051320 MAP1S_HUMAN (78-572): 4.1e-21: 100: 16.19		DCTN1_HUMAN (540-1022): 9.26e-59: 223: 16.33
+	Hs
		166047 SYNJ2_HUMAN (225-574): 1.83e-10: 66.4: 13.78		DCTN1_HUMAN (540-1022): 9.26e-59: 223: 16.33
+	Hs
		1051385 TITIN_HUMAN (39-550): 4.58e-09: 62: 10.17		DCTN1_HUMAN (540-1022): 9.26e-59: 223: 16.33
+	Hs
		1117441 TPRN_HUMAN (206-554): 4.48e-28: 121: 19.95		MY18A_HUMAN (461-1064): 4e-25: 115: 10.31
+	Hs
		724854 TPRN_HUMAN (206-554): 4.48e-28: 121: 19.95		MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40
+	Hs
		148893 TPRN_HUMAN (206-554): 4.48e-28: 121: 19.95		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		148818 MDC1_HUMAN (15-599): 3.32e-18: 91.2: 8.86		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		149173 CHAP1_HUMAN (231-585): 1.84e-15: 82: 11.05		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		149481 PCLO_HUMAN (17-601): 2.64e-11: 69.3: 7.19		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		551790 TITIN_HUMAN (39-550): 4.58e-09: 62: 10.17		DESP_HUMAN (570-1151): 1.05e-21: 104: 11.54
+	Hs
		1056879 MDC1_HUMAN (15-599): 3.32e-18: 91.2: 8.86		MYH14_HUMAN (620-918): 1.78e-11: 71.1: 13.11