Protein: GBRA1
Gamma-aminobutyric acid receptor subunit alpha-1 (GABA(A) receptor subunit alpha-1) (GABAAR subunit alpha-1)

Gene: GBRA1, GABRA1
Organism: Homo sapiens
Interactions: 134
UniProt ID: P14867

Gene Ontology (top 5):
GO:0004890 - GABA-A receptor activity
GO:0005886 - plasma membrane
GO:0007214 - gamma-aminobutyric acid signaling pathway
GO:0022851 - GABA-gated chloride ion channel activity
GO:0030659 - cytoplasmic vesicle membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

576625

GBRB2
Gamma-aminobutyric acid receptor subunit beta-2

2

18

Small-scale

0.754

High

576611

GBRG2
Gamma-aminobutyric acid receptor subunit gamma-2

2

18

Small-scale

0.737

High

576608

GBRA1
Gamma-aminobutyric acid receptor subunit alpha-1

1

18

High-throughput

0.618

High

576675

GBRG3
Gamma-aminobutyric acid receptor subunit gamma-3

1

18

Small-scale

0.618

High

573305

ENPL
Endoplasmin

2

3

Small-scale

0.570

High

576692

P2RX2
P2X purinoceptor 2

1

4

Small-scale

0.561

High

576699

UBQL1
Ubiquilin-1

1

9

Small-scale

0.552

High

576616

CALX
Calnexin

2

4

Small-scale

0.533

High

321170

ERLN2
Erlin-2

1

1

High-throughput

0.479

High

420335

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

2

High-throughput

0.479

High

424630

KPCG
Protein kinase C gamma type

1

3

Small-scale

0.479

High

424754

ADT2
ADP/ATP translocase 2

1

3

High-throughput

0.479

High

461103

HS90A
Heat shock protein HSP 90-alpha

1

3

High-throughput

0.479

High

462970

YES
Tyrosine-protein kinase Yes

1

2

High-throughput

0.479

High

468026

HS90B
Heat shock protein HSP 90-beta

1

3

High-throughput

0.479

High

532330

CH60
60 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.479

High

534583

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.479

High

536422

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.479

High

551942

ADT1
ADP/ATP translocase 1

1

3

High-throughput

0.479

High

576609

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

2

High-throughput

0.479

High

576610

HSP76
Heat shock 70 kDa protein 6

1

3

High-throughput

0.479

High

576645

S25A3
Solute carrier family 25 member 3

1

4

High-throughput

0.479

High

576646

KPCD
Protein kinase C delta type

1

3

Small-scale

0.479

High

576647

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

3

High-throughput

0.479

High

576660

ATD3B
ATPase family AAA domain-containing protein 3B

1

4

High-throughput

0.479

High

576662

TBA1A
Tubulin alpha-1A chain

1

6

High-throughput

0.479

High

576672

NEB2
Neurabin-2

1

8

High-throughput

0.479

High

576697

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

3

High-throughput

0.479

High

576698

MYO5B
Unconventional myosin-Vb

1

1

High-throughput

0.479

High

160406

IRS4
Insulin receptor substrate 4

1

0

High-throughput

0.458

High

299048

FLOT1
Flotillin-1

1

0

High-throughput

0.458

High

336337

SVIL
Supervillin

1

0

High-throughput

0.458

High

576618

MYH9
Myosin-9

1

0

High-throughput

0.458

High

576619

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.458

High

576629

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

0

High-throughput

0.458

High

576637

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

1

0

High-throughput

0.458

High

576638

EF1A1
Elongation factor 1-alpha 1

1

0

High-throughput

0.458

High

576653

EPN4
Clathrin interactor 1

1

0

High-throughput

0.458

High

576673

PHB2
Prohibitin-2

1

0

High-throughput

0.458

High

576676

DDX50
ATP-dependent RNA helicase DDX50

1

0

High-throughput

0.458

High

576690

ATX10
Ataxin-10

1

0

High-throughput

0.458

High

576696

LIMA1
LIM domain and actin-binding protein 1

1

0

High-throughput

0.458

High

105254

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

258748

DNJA2
DnaJ homolog subfamily A member 2

1

5

High-throughput

0.437

High

280483

PR40A
Pre-mRNA-processing factor 40 homolog A

1

2

High-throughput

0.437

High

317788

LTN1
E3 ubiquitin-protein ligase listerin

1

1

High-throughput

0.437

High

325669

UBR5
E3 ubiquitin-protein ligase UBR5

1

4

High-throughput

0.437

High

407968

TBB4A
Tubulin beta-4A chain

1

5

High-throughput

0.437

High

457205

TBB5
Tubulin beta chain

1

5

High-throughput

0.437

High

552108

ADT3
ADP/ATP translocase 3

1

3

High-throughput

0.437

High

576612

RO52
E3 ubiquitin-protein ligase TRIM21

1

1

High-throughput

0.437

High

576617

DNJA1
DnaJ homolog subfamily A member 1

1

5

High-throughput

0.437

High

576623

PRS6B
26S proteasome regulatory subunit 6B

1

1

High-throughput

0.437

High

576626

TCPE
T-complex protein 1 subunit epsilon

1

1

High-throughput

0.437

High

576628

SERPH
Serpin H1

1

1

High-throughput

0.437

High

576631

TXTP
Tricarboxylate transport protein, mitochondrial

1

4

High-throughput

0.437

High

576634

XPO2
Exportin-2

1

1

High-throughput

0.437

High

576635

TERA
Transitional endoplasmic reticulum ATPase

1

1

Small-scale

0.437

High

576636

PRS8
26S proteasome regulatory subunit 8

1

1

High-throughput

0.437

High

576639

TBA1B
Tubulin alpha-1B chain

1

6

High-throughput

0.437

High

576640

TBA4A
Tubulin alpha-4A chain

1

6

High-throughput

0.437

High

576641

TBB4B
Tubulin beta-4B chain

1

5

High-throughput

0.437

High

576642

TCPB
T-complex protein 1 subunit beta

1

2

High-throughput

0.437

High

576650

SQSTM
Sequestosome-1

1

2

High-throughput

0.437

High

576651

TBB3
Tubulin beta-3 chain

1

5

High-throughput

0.437

High

576654

GANAB
Neutral alpha-glucosidase AB

1

1

High-throughput

0.437

High

576656

UBE3C
Ubiquitin-protein ligase E3C

1

2

High-throughput

0.437

High

576659

KLH22
Kelch-like protein 22

1

1

High-throughput

0.437

High

576661

LRCH2
Leucine-rich repeat and calponin homology domain-containing protein 2

1

3

High-throughput

0.437

High

576664

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

1

High-throughput

0.437

High

576665

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

6

Small-scale

0.437

High

576667

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

1

High-throughput

0.437

High

576668

S39A7
Zinc transporter SLC39A7

1

2

High-throughput

0.437

High

576669

GCN1
Stalled ribosome sensor GCN1

1

1

High-throughput

0.437

High

576671

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

1

High-throughput

0.437

High

576674

TCPH
T-complex protein 1 subunit eta

1

1

High-throughput

0.437

High

576677

TBA1C
Tubulin alpha-1C chain

1

7

High-throughput

0.437

High

576679

TBB6
Tubulin beta-6 chain

1

5

High-throughput

0.437

High

576681

TBB2B
Tubulin beta-2B chain

1

5

High-throughput

0.437

High

576683

MYO5C
Unconventional myosin-Vc

1

1

High-throughput

0.437

High

576684

SMC4
Structural maintenance of chromosomes protein 4

1

1

High-throughput

0.437

High

576685

ATD3A
ATPase family AAA domain-containing protein 3A

1

3

High-throughput

0.437

High

576686

TBA8
Tubulin alpha-8 chain

1

6

High-throughput

0.437

High

576687

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

1

High-throughput

0.437

High

576691

COPG2
Coatomer subunit gamma-2

1

1

High-throughput

0.437

High

576693

DJB11
DnaJ homolog subfamily B member 11

1

5

High-throughput

0.437

High

576695

DIC
Mitochondrial dicarboxylate carrier

1

4

High-throughput

0.437

High

576700

MAGD2
Melanoma-associated antigen D2

1

1

High-throughput

0.437

High

576633

CLH2
Clathrin heavy chain 2

1

0

High-throughput

0.269

Low

122703

KIF2A
Kinesin-like protein KIF2A

1

0

High-throughput

0.249

Low

124221

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.249

Low

134233

RPOM
DNA-directed RNA polymerase, mitochondrial

1

0

High-throughput

0.249

Low

169050

ML12B
Myosin regulatory light chain 12B

1

0

High-throughput

0.249

Low

172446

XPO1
Exportin-1

1

0

High-throughput

0.249

Low

174916

SC16A
Protein transport protein Sec16A

1

0

High-throughput

0.249

Low

187878

EIF3H
Eukaryotic translation initiation factor 3 subunit H

1

0

High-throughput

0.249

Low

255564

DPM1
Dolichol-phosphate mannosyltransferase subunit 1

1

0

High-throughput

0.249

Low

333621

NDUAA
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

1

0

High-throughput

0.249

Low

335597

AGM1
Phosphoacetylglucosamine mutase

1

0

High-throughput

0.249

Low

351073

ECD
Protein ecdysoneless homolog

1

0

High-throughput

0.249

Low

417244

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.249

Low

417927

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

450919

LDHB
L-lactate dehydrogenase B chain

1

0

High-throughput

0.249

Low

452149

PDIA1
Protein disulfide-isomerase

1

0

High-throughput

0.249

Low

576613

LMNB1
Lamin-B1

1

0

High-throughput

0.249

Low

576614

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

0

High-throughput

0.249

Low

576615

PYR1
Multifunctional protein CAD

1

0

High-throughput

0.249

Low

576620

RFC3
Replication factor C subunit 3

1

0

High-throughput

0.249

Low

576621

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.249

Low

576622

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.249

Low

576624

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.249

Low

576627

EMD
Emerin

1

0

High-throughput

0.249

Low

576630

MSH6
DNA mismatch repair protein Msh6

1

0

High-throughput

0.249

Low

576632

COPA
Coatomer subunit alpha

1

0

High-throughput

0.249

Low

576643

PRKDC
DNA-dependent protein kinase catalytic subunit

1

0

High-throughput

0.249

Low

576644

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.249

Low

576648

LG3BP
Galectin-3-binding protein

1

0

High-throughput

0.249

Low

576649

OS9
Protein OS-9

1

0

Small-scale

0.249

Low

576652

RCN2
Reticulocalbin-2

1

0

High-throughput

0.249

Low

576655

PCM1
Pericentriolar material 1 protein

1

0

High-throughput

0.249

Low

576657

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.249

Low

576658

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

0

High-throughput

0.249

Low

576663

TRM1L
tRNA

1

0

High-throughput

0.249

Low

576666

LYRIC
Protein LYRIC

1

0

High-throughput

0.249

Low

576670

FUBP2
Far upstream element-binding protein 2

1

0

High-throughput

0.249

Low

576678

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.249

Low

576680

DDX23
Probable ATP-dependent RNA helicase DDX23

1

0

High-throughput

0.249

Low

576682

UN45A
Protein unc-45 homolog A

1

0

High-throughput

0.249

Low

576688

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.249

Low

576689

HACD3
Very-long-chain

1

0

High-throughput

0.249

Low

576694

SE1L1
Protein sel-1 homolog 1

1

0

High-throughput

0.249

Low

576701

SYFA
Phenylalanine--tRNA ligase alpha subunit

1

0

High-throughput

0.249

Low

576702

YTHD2
YTH domain-containing family protein 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025