HitPredict

Interactor 1: L2GL2 (Q6P1M3)
LLGL scribble cell polarity complex component 2 (HGL) (Lethal(2) giant larvae protein homolog 2)
Gene: LLGL2

Interactor 2: BRWD3 (Q6RI45)
Bromodomain and WD repeat-containing protein 3
Gene: BRWD3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.80	0.726

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LLGL~WD40, WD40~WD40
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1020 Hs			1 1802
+	Hs
		1071586 L2GL1_HUMAN (3-965): 0: 1085: 56.79		FBW1B_HUMAN (183-495): 1.87e-12: 73.9: 24.46
+	Hs
		1016282 PWP2_HUMAN (28-330): 1.35e-64: 237: 15.46		TBL3_HUMAN (1-437): 6.33e-71: 257: 13.48
+	Hs
		1066965 PWP2_HUMAN (28-330): 1.35e-64: 237: 15.46		BRD3_HUMAN (1133-1302): 2.39e-35: 147: 18.86
+	Hs
		903174 WDR5_HUMAN (29-216): 7.81e-21: 96.9: 12.50		TBL3_HUMAN (1-437): 6.33e-71: 257: 13.48
+	Hs
		903349 WDR5_HUMAN (29-216): 7.81e-21: 96.9: 12.50		WDR5B_HUMAN (68-345): 2.77e-66: 230: 17.02
+	Hs
		1240442 POC1A_HUMAN (30-282): 9.66e-28: 118: 12.55		POC1B_HUMAN (349-791): 2.25e-53: 197: 11.30
+	Dm
		1358845 WDS_DROME (29-216): 4.08e-20: 95.3: 12.50		WDS_DROME (411-658): 3.9e-49: 181: 13.26
+	Hs
		903418 WDR5_HUMAN (29-216): 7.81e-21: 96.9: 12.50		FBXW7_HUMAN (395-683): 2.37e-42: 169: 12.93
+	Hs
		792949 WDR5_HUMAN (29-216): 7.81e-21: 96.9: 12.50		LIS1_HUMAN (411-692): 6.51e-41: 158: 12.63
+	Hs
		903077 WDR5_HUMAN (29-216): 7.81e-21: 96.9: 12.50		WDR5_HUMAN (453-689): 3.34e-36: 143: 12.30
+	Hs
		792935 LIS1_HUMAN (44-157): 1.21e-13: 76.1: 21.74		LIS1_HUMAN (411-692): 6.51e-41: 158: 12.63
+	Mm
		925836 LIS1_MOUSE (44-157): 1.17e-13: 76.1: 21.74		LIS1_MOUSE (411-692): 6.39e-41: 158: 12.63
+	Dm
		1358859 WDS_DROME (29-216): 4.08e-20: 95.3: 12.50		FBXW7_DROME (399-573): 8.09e-26: 118: 15.64
+	Sc
		635644 PWP2_YEAST (22-654): 3.23e-16: 86.1: 11.65		UTP13_YEAST (268-669): 5.88e-19: 95.7: 9.94
+	Hs
		903428 WDR5_HUMAN (29-216): 7.81e-21: 96.9: 12.50		SNR40_HUMAN (22-206): 1.57e-15: 82.2: 15.10
+	Hs
		903551 WDR5_HUMAN (29-216): 7.81e-21: 96.9: 12.50		NLE1_HUMAN (1-78): 7.24e-15: 81.5: 12.82
+	Hs
		793026 LIS1_HUMAN (44-157): 1.21e-13: 76.1: 21.74		KTNB1_HUMAN (174-395): 1.16e-18: 94.4: 29.15