HitPredict

Interactor 1: L2GL2 (Q6P1M3)
LLGL scribble cell polarity complex component 2 (HGL) (Lethal(2) giant larvae protein homolog 2)
Gene: LLGL2

Interactor 2: DCAF1 (Q9Y4B6)
DDB1- and CUL4-associated factor 1 (HIV-1 Vpr-binding protein) (VprBP) (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) (Vpr-interacting protein)
Gene: DCAF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	26496610, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1020 Hs			1 1507
+	Dm
		435908 L2GL_DROME (1-944): 0: 842: 35.12		DCAF1_DROME (10-1393): 0: 1421: 38.55
+	Dm
		1358859 WDS_DROME (29-216): 4.08e-20: 95.3: 12.50		FBXW7_DROME (886-1383): 1.41e-92: 330: 14.29
+	Dm
		1358845 WDS_DROME (29-216): 4.08e-20: 95.3: 12.50		WDS_DROME (955-1290): 3.42e-70: 242: 13.80
+	Hs
		903077 WDR5_HUMAN (29-216): 7.81e-21: 96.9: 12.50		WDR5_HUMAN (923-1244): 5.84e-46: 171: 13.02
+	Hs
		903418 WDR5_HUMAN (29-216): 7.81e-21: 96.9: 12.50		FBXW7_HUMAN (1039-1242): 6.77e-37: 152: 9.64
+	Hs
		196984 WDR5_HUMAN (29-216): 7.81e-21: 96.9: 12.50		PRP4_HUMAN (1178-1389): 5.63e-30: 128: 11.74
+	Hs
		903551 WDR5_HUMAN (29-216): 7.81e-21: 96.9: 12.50		NLE1_HUMAN (972-1164): 2.95e-28: 122: 14.43
+	Hs
		903349 WDR5_HUMAN (29-216): 7.81e-21: 96.9: 12.50		WDR5B_HUMAN (1207-1379): 3.77e-28: 119: 10.33
+	Hs
		903109 WDR5_HUMAN (29-216): 7.81e-21: 96.9: 12.50		RACK1_HUMAN (1049-1209): 4.28e-28: 118: 10.86
+	Hs
		792967 LIS1_HUMAN (44-157): 1.21e-13: 76.1: 21.74		RACK1_HUMAN (1049-1209): 4.28e-28: 118: 10.86
+	Hs
		1240442 POC1A_HUMAN (30-282): 9.66e-28: 118: 12.55		POC1B_HUMAN (1039-1120): 1.63e-10: 67.5: 12.20
+	Hs
		793026 LIS1_HUMAN (44-157): 1.21e-13: 76.1: 21.74		KTNB1_HUMAN (1066-1211): 2.14e-23: 109: 14.77
+	Hs
		792949 WDR5_HUMAN (29-216): 7.81e-21: 96.9: 12.50		LIS1_HUMAN (1255-1393): 1.71e-14: 79.5: 10.14
+	Hs
		903605 WDR5_HUMAN (29-216): 7.81e-21: 96.9: 12.50		PRP19_HUMAN (1068-1205): 4.06e-13: 76: 14.09
+	Hs
		792935 LIS1_HUMAN (44-157): 1.21e-13: 76.1: 21.74		LIS1_HUMAN (1255-1393): 1.71e-14: 79.5: 10.14
+	Mm
		925836 LIS1_MOUSE (44-157): 1.17e-13: 76.1: 21.74		LIS1_MOUSE (1255-1393): 1.71e-14: 79.5: 10.14