HitPredict

Interactor 1: CEP85 (Q6P2H3)
Centrosomal protein of 85 kDa (Cep85) (Coiled-coil domain-containing protein 21)
Gene: CEP85

Interactor 2: CEP63 (Q96MT8)
Centrosomal protein of 63 kDa (Cep63)
Gene: CEP63

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	24613305, 26638075
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000922 - spindle pole GO:0005813 - centrosome GO:0005814 - centriole GO:0005829 - cytosol GO:0007099 - centriole replication
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 762 Hs			1 703
+	Hs
		985709 CEP85_HUMAN (1-762): 9.11e-72: 251: 100.00		DEUP1_HUMAN (8-523): 1.03e-62: 221: 28.30
+	Hs
		724969 MYH9_HUMAN (396-760): 3.11e-16: 85.6: 12.06		CEP63_HUMAN (1-703): 1.84e-64: 228: 100.00
+	Hs
		1137103 CROCC_HUMAN (115-655): 1.33e-14: 80.2: 10.54		CEP63_HUMAN (1-703): 1.84e-64: 228: 100.00
+	Hs
		725097 MYH10_HUMAN (104-690): 5.89e-23: 107: 10.46		MYH11_HUMAN (1-585): 5.28e-26: 116: 10.94
+	Hs
		725035 MYO5C_HUMAN (278-761): 3.69e-28: 124: 13.05		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		725095 MYH10_HUMAN (104-690): 5.89e-23: 107: 10.46		MYH10_HUMAN (145-703): 1.35e-24: 112: 10.78
+	Hs
		724687 MYH10_HUMAN (104-690): 5.89e-23: 107: 10.46		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		1268099 MYO5C_HUMAN (278-761): 3.69e-28: 124: 13.05		MY18A_HUMAN (51-572): 5.91e-15: 81.2: 16.15
+	Hs
		148461 MYH10_HUMAN (104-690): 5.89e-23: 107: 10.46		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		148466 MYH11_HUMAN (106-655): 5.98e-21: 101: 10.31		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		724686 MYH9_HUMAN (396-760): 3.11e-16: 85.6: 12.06		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		1268126 MRCKB_HUMAN (358-757): 3.54e-20: 98.5: 12.80		MY18A_HUMAN (51-572): 5.91e-15: 81.2: 16.15
+	Hs
		148460 MYH9_HUMAN (396-760): 3.11e-16: 85.6: 12.06		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		1067423 EEA1_HUMAN (92-676): 3.33e-18: 91.8: 10.59		EEA1_HUMAN (231-701): 8.23e-14: 77.5: 11.62
+	Hs
		724943 MYH9_HUMAN (396-760): 3.11e-16: 85.6: 12.06		MY18A_HUMAN (51-572): 5.91e-15: 81.2: 16.15
+	Mm
		93570 MYH9_MOUSE (51-655): 1.23e-21: 103: 10.88		DESP_MOUSE (59-550): 4.18e-09: 62.5: 18.91
+	Rn
		222472 MRCKA_RAT (390-752): 1.69e-19: 96.3: 11.97		MRCKA_RAT (80-483): 2.52e-09: 62.9: 16.67
+	Hs
		724994 MYH9_HUMAN (396-760): 3.11e-16: 85.6: 12.06		CP250_HUMAN (150-696): 7.75e-10: 64.8: 11.94