Interactor 1: RICTR (Q6QI06)
Rapamycin-insensitive companion of mTOR (AVO3 homolog) (mAVO3) (Protein pianissimo)
Gene: Rictor

Interactor 2: MTOR (Q9JLN9)
Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin target protein 1) (RAPT1)
Gene: MTOR

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.978

The method score is based on:

Property Details
Experiments 18664580, 27340174, 20801936, 18851840, 22307628, 17141160, 16221682, 18925875, 18614546, 18505677, 18426911, 18566586, 21045808
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains FRB_dom~RICTOR_N
Common GO terms GO:0001932 - regulation of protein phosphorylation
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0007010 - cytoskeleton organization
GO:0019901 - protein kinase binding
GO:0030307 - positive regulation of cell growth
and 9 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 1708
Mm

1 2549
+ Hs
+ Hs
+ Hs
+ Sp
+ Sc
+ Hs
+ Sp
+ Ce
+ Dm

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Last updated: 15 Jul 2024