Protein: CN37
2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) (CNPase) (EC 3.1.4.37)

Gene: CN37, CNP
Organism: Homo sapiens
Interactions: 197
UniProt ID: P09543

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0004113 - 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity
GO:0005615 - extracellular space
GO:0005737 - cytoplasm
GO:0005741 - mitochondrial outer membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

451973

SIR3
NAD-dependent protein deacetylase sirtuin-3, mitochondrial

3

2

High-throughput

0.599

High

451858

HD
Huntingtin

2

1

High-throughput

0.588

High

451892

NMI
N-myc-interactor

2

0

High-throughput

0.585

High

226325

PRKN
E3 ubiquitin-protein ligase parkin

2

3

High-throughput

0.584

High

345756

MYC
Myc proto-oncogene protein

2

1

High-throughput

0.584

High

349817

RASK
GTPase KRas

2

5

High-throughput

0.584

High

451834

LAMP1
Lysosome-associated membrane glycoprotein 1

2

2

High-throughput

0.584

High

451883

RHOB
Rho-related GTP-binding protein RhoB

2

5

High-throughput

0.584

High

368851

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

451925

ZDH17
Palmitoyltransferase ZDHHC17

1

5

High-throughput

0.568

High

451832

TAU
Microtubule-associated protein tau

2

2

Small-scale

0.552

High

408530

KPCB
Protein kinase C beta type

2

0

High-throughput

0.547

High

427978

TBB5
Tubulin beta chain

1

1

High-throughput

0.536

High

435503

IGF1R
Insulin-like growth factor 1 receptor

1

5

High-throughput

0.536

High

451830

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

2

High-throughput

0.536

High

451860

GRK6
G protein-coupled receptor kinase 6

1

1

High-throughput

0.536

High

451864

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.536

High

451869

IRAK1
Interleukin-1 receptor-associated kinase 1

1

1

High-throughput

0.536

High

451893

ILK
Integrin-linked protein kinase

1

1

High-throughput

0.536

High

451898

TBB2A
Tubulin beta-2A chain

1

1

High-throughput

0.536

High

451914

PKN3
Serine/threonine-protein kinase N3

1

1

High-throughput

0.536

High

451953

STK33
Serine/threonine-protein kinase 33

1

2

High-throughput

0.536

High

384141

NTRK1
High affinity nerve growth factor receptor

2

5

High-throughput

0.533

High

451909

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

0

High-throughput

0.528

High

451938

ESR2
Estrogen receptor beta

2

1

High-throughput

0.521

High

160895

RAB7L
Ras-related protein Rab-7L1

1

4

High-throughput

0.515

High

153072

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

1

0

High-throughput

0.513

High

451851

PCKGC
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

1

0

High-throughput

0.513

High

451870

LIMK2
LIM domain kinase 2

1

0

High-throughput

0.513

High

451899

CDK13
Cyclin-dependent kinase 13

1

0

High-throughput

0.513

High

451924

HPS6
BLOC-2 complex member HPS6

1

0

High-throughput

0.513

High

451934

F174A
Membrane protein FAM174A

1

0

High-throughput

0.513

High

451959

IL25
Interleukin-25

1

0

High-throughput

0.513

High

451971

DYRK4
Dual specificity tyrosine-phosphorylation-regulated kinase 4

1

0

High-throughput

0.513

High

451980

DBNL
Drebrin-like protein

1

0

High-throughput

0.513

High

451981

INTU
Protein inturned

1

0

High-throughput

0.513

High

451831

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

2

High-throughput

0.501

High

451843

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.493

High

451867

ACOT2
Acyl-coenzyme A thioesterase 2, mitochondrial

1

1

High-throughput

0.489

High

451919

ERN2
Serine/threonine-protein kinase/endoribonuclease IRE2

1

1

High-throughput

0.489

High

451921

ACOT1
Acyl-coenzyme A thioesterase 1

1

1

High-throughput

0.489

High

451946

PSKH2
Serine/threonine-protein kinase H2

1

1

High-throughput

0.489

High

451964

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

2

High-throughput

0.489

High

451991

RPKL1
Ribosomal protein S6 kinase-like 1

1

2

High-throughput

0.489

High

451879

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

0

Small-scale

0.486

High

261947

PEX14
Peroxisomal membrane protein PEX14

1

1

Small-scale

0.484

High

100412

APRIO
Alternative prion protein

1

0

Small-scale

0.480

High

377892

PRIO
Major prion protein

1

0

Small-scale

0.480

High

150826

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

1

High-throughput

0.479

High

282805

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

3

High-throughput

0.479

High

322099

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

337817

EGFR
Epidermal growth factor receptor

1

2

High-throughput

0.479

High

348478

RASN
GTPase NRas

1

5

High-throughput

0.479

High

349078

RASH
GTPase HRas

1

3

High-throughput

0.479

High

383549

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

2

High-throughput

0.479

High

411562

LCK
Tyrosine-protein kinase Lck

1

1

High-throughput

0.479

High

433534

LYN
Tyrosine-protein kinase Lyn

1

1

High-throughput

0.479

High

436128

RHOC
Rho-related GTP-binding protein RhoC

1

4

High-throughput

0.479

High

451835

FGFR1
Fibroblast growth factor receptor 1

1

7

High-throughput

0.479

High

451836

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.479

High

451837

LAMP2
Lysosome-associated membrane glycoprotein 2

1

2

High-throughput

0.479

High

451839

RHOQ
Rho-related GTP-binding protein RhoQ

1

6

High-throughput

0.479

High

451841

VGFR1
Vascular endothelial growth factor receptor 1

1

5

High-throughput

0.479

High

451845

LTK
Leukocyte tyrosine kinase receptor

1

5

High-throughput

0.479

High

451847

UFO
Tyrosine-protein kinase receptor UFO

1

3

High-throughput

0.479

High

451868

RAB9A
Ras-related protein Rab-9A

1

2

High-throughput

0.479

High

451874

CDC42
Cell division control protein 42 homolog

1

6

High-throughput

0.479

High

451875

RAB2A
Ras-related protein Rab-2A

1

1

High-throughput

0.479

High

451876

RHOA
Transforming protein RhoA

1

4

High-throughput

0.479

High

451884

RAC1
Ras-related C3 botulinum toxin substrate 1

1

5

High-throughput

0.479

High

451886

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.479

High

451887

ROR1
Inactive tyrosine-protein kinase transmembrane receptor ROR1

1

7

High-throughput

0.479

High

451895

SQSTM
Sequestosome-1

1

1

High-throughput

0.479

High

451900

SCRB2
Lysosome membrane protein 2

1

1

High-throughput

0.479

High

451903

RAB35
Ras-related protein Rab-35

1

1

High-throughput

0.479

High

451904

RHOH
Rho-related GTP-binding protein RhoH

1

6

High-throughput

0.479

High

451905

DUS7
Dual specificity protein phosphatase 7

1

1

High-throughput

0.479

High

451912

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

451915

LMTK1
Serine/threonine-protein kinase LMTK1

1

6

High-throughput

0.479

High

451917

TBA1A
Tubulin alpha-1A chain

1

1

High-throughput

0.479

High

451930

FBXW8
F-box/WD repeat-containing protein 8

1

2

High-throughput

0.479

High

451939

FBXW7
F-box/WD repeat-containing protein 7

1

1

High-throughput

0.479

High

451950

ANM1
Protein arginine N-methyltransferase 1

1

2

High-throughput

0.479

High

451954

TRI31
E3 ubiquitin-protein ligase TRIM31

1

1

High-throughput

0.479

High

451956

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

2

High-throughput

0.479

High

451961

Q9H4D1
Protein kinase

1

2

High-throughput

0.479

High

451962

RHOJ
Rho-related GTP-binding protein RhoJ

1

6

High-throughput

0.479

High

451963

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

451966

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.479

High

451969

BRD7
Bromodomain-containing protein 7

1

2

High-throughput

0.479

High

451977

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

451983

LAMP3
Lysosome-associated membrane glycoprotein 3

1

2

High-throughput

0.479

High

451985

CIA2B
Cytosolic iron-sulfur assembly component 2B

1

2

High-throughput

0.479

High

451986

TRAF6
TNF receptor-associated factor 6

1

2

High-throughput

0.479

High

451990

OAS3
2'-5'-oligoadenylate synthase 3

1

1

High-throughput

0.479

High

169369

BET1
BET1 homolog

1

0

High-throughput

0.458

High

178370

STX7
Syntaxin-7

1

0

High-throughput

0.458

High

233165

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

298082

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

351902

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.458

High

359588

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

373568

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

451833

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

451840

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

451846

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

451848

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.458

High

451849

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

451852

BASI
Basigin

1

0

High-throughput

0.458

High

451856

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

451857

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

451859

MUC18
Cell surface glycoprotein MUC18

1

0

High-throughput

0.458

High

451861

IF2M
Translation initiation factor IF-2, mitochondrial

1

0

High-throughput

0.458

High

451862

MAP1B
Microtubule-associated protein 1B

1

0

High-throughput

0.458

High

451866

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

451871

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

451881

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.458

High

451882

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.458

High

451885

CXAR
Coxsackievirus and adenovirus receptor

1

0

High-throughput

0.458

High

451888

CAV1
Caveolin-1

1

0

High-throughput

0.458

High

451891

TADBP
TAR DNA-binding protein 43

1

0

Small-scale

0.458

High

451894

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

0

High-throughput

0.458

High

451896

CUL3
Cullin-3

1

0

High-throughput

0.458

High

451897

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

0

High-throughput

0.458

High

451901

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

451902

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

451907

CRY2
Cryptochrome-2

1

0

High-throughput

0.458

High

451910

RC3H1
Roquin-1

1

0

High-throughput

0.458

High

451911

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

451916

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

451927

TM192
Transmembrane protein 192

1

0

High-throughput

0.458

High

451931

CGAS
Cyclic GMP-AMP synthase

1

0

High-throughput

0.458

High

451932

RN149
E3 ubiquitin-protein ligase RNF149

1

0

High-throughput

0.458

High

451936

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

451940

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.458

High

451944

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

451948

RUFY1
RUN and FYVE domain-containing protein 1

1

0

High-throughput

0.458

High

451949

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.458

High

451951

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

0

High-throughput

0.458

High

451952

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

451958

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

451960

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

451974

MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial

1

0

High-throughput

0.458

High

451976

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.458

High

451872

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

1

High-throughput

0.445

High

451873

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

2

High-throughput

0.445

High

451913

PKHA7
Pleckstrin homology domain-containing family A member 7

1

2

High-throughput

0.445

High

451955

ZDHC5
Palmitoyltransferase ZDHHC5

1

1

High-throughput

0.445

High

451984

ITM2B
Integral membrane protein 2B

1

1

High-throughput

0.445

High

451989

SIR4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

1

2

High-throughput

0.445

High

318054

DIRA3
GTP-binding protein Di-Ras3

1

1

High-throughput

0.437

High

378938

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.437

High

451842

FGFR3
Fibroblast growth factor receptor 3

1

6

High-throughput

0.437

High

451844

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

451850

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

451853

VGFR3
Vascular endothelial growth factor receptor 3

1

5

High-throughput

0.437

High

451854

VGFR2
Vascular endothelial growth factor receptor 2

1

5

High-throughput

0.437

High

451855

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

5

High-throughput

0.437

High

451877

RND3
Rho-related GTP-binding protein RhoE

1

7

High-throughput

0.437

High

451878

WDR5
WD repeat-containing protein 5

1

2

High-throughput

0.437

High

451880

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.437

High

451918

ASXL2
Putative Polycomb group protein ASXL2

1

1

High-throughput

0.437

High

451920

RHOU
Rho-related GTP-binding protein RhoU

1

7

High-throughput

0.437

High

451926

ASXL1
Polycomb group protein ASXL1

1

1

High-throughput

0.437

High

451928

MKX
Homeobox protein Mohawk

1

1

High-throughput

0.437

High

451937

RND1
Rho-related GTP-binding protein Rho6

1

7

High-throughput

0.437

High

451945

SNX27
Sorting nexin-27

1

1

High-throughput

0.437

High

451947

CIC
Protein capicua homolog

1

1

High-throughput

0.437

High

275366

PR15A
Protein phosphatase 1 regulatory subunit 15A

1

0

High-throughput

0.426

High

451968

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.426

High

451863

MTR1A
Melatonin receptor type 1A

2

0

Small-scale

0.313

High

63989

SPDE4
Speedy protein E4

1

0

High-throughput

0.279

Low

451889

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.279

Low

451890

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

0

High-throughput

0.279

Low

451922

ST32C
Serine/threonine-protein kinase 32C

1

0

High-throughput

0.279

Low

451923

TMM25
Transmembrane protein 25

1

0

High-throughput

0.279

Low

451942

RMC1
Regulator of MON1-CCZ1 complex

1

0

High-throughput

0.279

Low

451943

AURKB
Aurora kinase B

1

0

High-throughput

0.279

Low

451967

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.279

Low

451972

LATS2
Serine/threonine-protein kinase LATS2

1

0

High-throughput

0.279

Low

451978

MRM2
rRNA methyltransferase 2, mitochondrial

1

0

High-throughput

0.279

Low

451979

ZF69B
Zinc finger protein 69 homolog B

1

0

High-throughput

0.279

Low

451982

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.279

Low

451987

NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2

1

0

High-throughput

0.279

Low

451988

GPR45
Probable G-protein coupled receptor 45

1

0

High-throughput

0.279

Low

204957

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

451838

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

451865

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

0

High-throughput

0.249

Low

451906

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

451908

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.249

Low

451929

CXD3
Gap junction delta-3 protein

1

0

High-throughput

0.249

Low

451933

DPTOR
DEP domain-containing mTOR-interacting protein

1

0

Small-scale

0.249

Low

451935

CLC4D
C-type lectin domain family 4 member D

1

0

High-throughput

0.249

Low

451941

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.249

Low

451957

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.249

Low

451965

ANTR1
Anthrax toxin receptor 1

1

0

Small-scale

0.249

Low

451970

ANLN
Anillin

1

0

High-throughput

0.249

Low

451975

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024