HitPredict

Interactor 1: LRIG3 (Q6UXM1)
Leucine-rich repeats and immunoglobulin-like domains protein 3 (LIG-3)
Gene: LRIG3

Interactor 2: LRC4C (Q9HCJ2)
Leucine-rich repeat-containing protein 4C (Netrin-G1 ligand) (NGL-1)
Gene: LRRC4C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	I-set~I-set, I-set~LRR_8, Ig_3~I-set, Ig_3~LRR_8, LRR_1~LRR_1, LRR_1~LRR_8, LRR_8~LRR_8
Common GO terms	GO:0005615 - extracellular space GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1119 Hs			1 640
+	Hs
		259500 LRIG3_HUMAN (2-1119): 0: 769: 100.00		LRRN2_HUMAN (20-543): 6.08e-54: 198: 20.25
+	Hs
		1166661 LRIG3_HUMAN (2-1119): 0: 769: 100.00		LRIG1_HUMAN (359-505): 5.97e-09: 61.3: 19.87
+	At
		1114682 ERECT_ARATH (1-610): 7.14e-111: 371: 16.86		ERECT_ARATH (1-278): 1.47e-47: 181: 19.86
+	At
		1114706 ERECT_ARATH (1-610): 7.14e-111: 371: 16.86		PXL1_ARATH (55-470): 2.61e-44: 172: 14.52
+	At
		84466 ERECT_ARATH (1-610): 7.14e-111: 371: 16.86		GSO1_ARATH (82-481): 7.22e-39: 156: 15.06
+	At
		1114702 ERECT_ARATH (1-610): 7.14e-111: 371: 16.86		TDR_ARATH (60-485): 1.88e-38: 154: 16.98
+	At
		85352 ERECT_ARATH (1-610): 7.14e-111: 371: 16.86		ERL1_ARATH (7-214): 1.38e-34: 142: 17.54
+	At
		84487 GSO1_ARATH (24-569): 7.63e-88: 311: 18.66		PEPR2_ARATH (62-482): 3.74e-50: 190: 16.00
+	At
		1352203 Y1723_ARATH (30-567): 2.56e-89: 313: 17.85		BRL2_ARATH (1-411): 1.36e-48: 185: 13.48
+	At
		1338065 RGI1_ARATH (1-397): 1.45e-88: 312: 19.46		BRL2_ARATH (1-411): 1.36e-48: 185: 13.48
+	At
		84509 GSO1_ARATH (24-569): 7.63e-88: 311: 18.66		BRL2_ARATH (1-411): 1.36e-48: 185: 13.48
+	At
		1338063 RGI1_ARATH (1-397): 1.45e-88: 312: 19.46		PXC2_ARATH (1-333): 4.39e-47: 180: 15.05
+	At
		84497 GSO1_ARATH (24-569): 7.63e-88: 311: 18.66		PXC2_ARATH (1-333): 4.39e-47: 180: 15.05
+	At
		1114685 ERECT_ARATH (1-610): 7.14e-111: 371: 16.86		ERL2_ARATH (8-195): 2.95e-20: 97.6: 14.89
+	At
		84451 Y4361_ARATH (33-692): 1.21e-84: 300: 16.28		GSO1_ARATH (82-481): 7.22e-39: 156: 15.06
+	At
		84728 Y4361_ARATH (33-692): 1.21e-84: 300: 16.28		ERL1_ARATH (7-214): 1.38e-34: 142: 17.54
+	At
		84461 GSO1_ARATH (24-569): 7.63e-88: 311: 18.66		SKM1_ARATH (1-171): 8.79e-31: 130: 16.48
+	At
		85344 ERL1_ARATH (1-402): 3.91e-85: 299: 21.21		ERL1_ARATH (7-214): 1.38e-34: 142: 17.54
+	At
		84489 GSO1_ARATH (24-569): 7.63e-88: 311: 18.66		BRL3_ARATH (105-524): 3.38e-25: 113: 15.81