HitPredict

Interactor 1: DLK2 (Q6UY11)
Protein delta homolog 2 (DLK-2) (Epidermal growth factor-like protein 9) (EGF-like protein 9)
Gene: DLK2

Interactor 2: LRC8A (Q8IWT6)
Volume-regulated anion channel subunit LRRC8A (Leucine-rich repeat-containing protein 8A) (HsLRRC8A) (Swelling protein 1)
Gene: LRRC8A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 383 Hs			1 810
+	Hs
		1049987 DLK2_HUMAN (1-383): 5.01e-57: 192: 100.00		SCRIB_HUMAN (345-673): 1.08e-54: 207: 25.83
+	Hs
		1155891 DLK2_HUMAN (1-383): 5.01e-57: 192: 100.00		LRC8E_HUMAN (493-808): 2.71e-29: 127: 24.70
+	Dm
		422751 NOTCH_DROME (8-254): 4.99e-15: 78.9: 19.93		FLII_DROME (652-799): 3.32e-11: 69.3: 28.67
+	Dm
		422829 NOTCH_DROME (8-254): 4.99e-15: 78.9: 19.93		LAP1_DROME (690-779): 2.92e-09: 62.8: 35.56