Protein: TBX6
T-box transcription factor TBX6 (T-box protein 6)

Gene: TBX6
Organism: Homo sapiens
Interactions: 39
UniProt ID: O95947

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001708 - cell fate specification

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

209937

CRX
Cone-rod homeobox protein

2

13

High-throughput

0.783

High

256523

TBX19
T-box transcription factor TBX19

2

12

High-throughput

0.783

High

351433

PO6F2
POU domain, class 6, transcription factor 2

2

11

High-throughput

0.783

High

351457

TBX15
T-box transcription factor TBX15

2

12

High-throughput

0.783

High

318428

TOX4
TOX high mobility group box family member 4

4

12

High-throughput

0.705

High

351453

RBPMS
RNA-binding protein with multiple splicing

4

2

High-throughput

0.705

High

351456

HSFY1
Heat shock transcription factor, Y-linked

4

1

High-throughput

0.705

High

351431

MEOX2
Homeobox protein MOX-2

1

18

High-throughput

0.621

High

351436

TLE5
TLE family member 5

2

20

High-throughput

0.606

High

351454

TET5B
Terminal nucleotidyltransferase 5B

2

2

High-throughput

0.606

High

192050

PA2GX
Group 10 secretory phospholipase A2

2

0

High-throughput

0.580

High

351437

DAZP2
DAZ-associated protein 2

2

0

High-throughput

0.580

High

351438

OBF1
POU domain class 2-associating factor 1

2

0

High-throughput

0.580

High

351444

INT11
Integrator complex subunit 11

2

0

High-throughput

0.580

High

351461

MAGD1
Melanoma-associated antigen D1

2

0

High-throughput

0.580

High

70068

CRTP1
Cysteine-rich tail protein 1

2

1

High-throughput

0.553

High

351455

KLD7B
Kelch domain-containing protein 7B

2

1

High-throughput

0.553

High

351458

ANM1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.508

High

351429

PSA3
Proteasome subunit alpha type-3

1

3

High-throughput

0.481

High

351450

ZNF34
Zinc finger protein 34

1

1

High-throughput

0.481

High

351452

TSC1
Hamartin

1

5

High-throughput

0.481

High

351434

PR20D
Proline-rich protein 20D

1

3

High-throughput

0.470

High

351440

KRA63
Keratin-associated protein 6-3

1

1

High-throughput

0.470

High

351447

Q86WV8
TSC complex subunit 1

1

1

High-throughput

0.470

High

351460

UBQL1
Ubiquilin-1

1

1

High-throughput

0.470

High

351435

PR20A
Proline-rich protein 20A

1

3

High-throughput

0.439

High

351445

CA094
Uncharacterized protein C1orf94

2

0

High-throughput

0.337

High

351439

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.316

High

351442

ACTMP
Actin maturation protease

2

0

High-throughput

0.316

High

351443

CJ055
Uncharacterized protein C10orf55

2

0

High-throughput

0.316

High

351446

UBP54
Ubiquitin carboxyl-terminal hydrolase 54

2

0

High-throughput

0.316

High

351449

KR111
Keratin-associated protein 11-1

2

0

High-throughput

0.316

High

351451

MET27
Methyltransferase-like protein 27

2

0

High-throughput

0.316

High

351459

T11L1
T-complex protein 11-like protein 1

2

0

High-throughput

0.316

High

351428

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.268

Low

351430

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

0

High-throughput

0.268

Low

351432

YPEL3
Protein yippee-like 3

1

0

High-throughput

0.251

Low

351441

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.251

Low

351448

KR131
Keratin-associated protein 13-1

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025