HitPredict

Interactor 1: RBP10 (Q6VN20)
Ran-binding protein 10 (RanBP10)
Gene: RANBP10

Interactor 2: RMD5A (Q9H871)
E3 ubiquitin-protein transferase RMND5A (EC 2.3.2.27) (P44CTLH) (Protein RMD5 homolog A)
Gene: RMND5A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.90	1.00	0.950

Property	Details
Experiments	26186194, 28514442, 27173435, 29911972, 33961781, 35271311
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	CTLH~CTLH, CTLH~LisH
Common GO terms	GO:0000151 - ubiquitin ligase complex GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 620 Hs			1 391
+	Hs
		1167162 RBP10_HUMAN (1-620): 0: 751: 100.00		RMD5B_HUMAN (1-391): 2.2e-152: 437: 69.72
+	Hs
		1301794 RANB9_HUMAN (19-620): 0: 665: 66.77		RMD5A_HUMAN (1-391): 2.58e-160: 457: 100.00
+	Hs
		1291934 RANB9_HUMAN (19-620): 0: 665: 66.77		RMD5B_HUMAN (1-391): 2.2e-152: 437: 69.72
+	Hs
		1167148 RBP10_HUMAN (1-620): 0: 751: 100.00		MAEA_HUMAN (25-390): 1.22e-111: 334: 20.05
+	Hs
		1185138 RANB9_HUMAN (19-620): 0: 665: 66.77		MAEA_HUMAN (25-390): 1.22e-111: 334: 20.05
+	Hs
		1167186 RBP10_HUMAN (1-620): 0: 751: 100.00		GID8_HUMAN (114-280): 5.61e-39: 141: 17.54
+	Hs
		1167168 RBP10_HUMAN (1-620): 0: 751: 100.00		RANB9_HUMAN (87-214): 3.61e-11: 66.7: 16.41
+	Hs
		1301810 RANB9_HUMAN (19-620): 0: 665: 66.77		GID8_HUMAN (114-280): 5.61e-39: 141: 17.54
+	Hs
		1301759 RANB9_HUMAN (19-620): 0: 665: 66.77		RANB9_HUMAN (87-214): 3.61e-11: 66.7: 16.41
+	Dm
		1119173 RBP9X_DROME (21-617): 0: 567: 47.26		Q9VWS1_DROME (114-281): 3.32e-34: 128: 17.75
+	Hs
		1291946 GID8_HUMAN (232-441): 2.28e-48: 170: 14.35		RMD5B_HUMAN (1-391): 2.2e-152: 437: 69.72
+	Sc
		858915 VID30_YEAST (116-602): 2.54e-96: 317: 19.88		RMD5_YEAST (10-391): 2.85e-90: 280: 24.22
+	Dm
		1375220 Q9VWS1_DROME (233-441): 7.78e-49: 171: 15.91		Q9W2N5_DROME (58-391): 2.14e-116: 347: 45.75
+	Hs
		1185162 GID8_HUMAN (232-441): 2.28e-48: 170: 14.35		MAEA_HUMAN (25-390): 1.22e-111: 334: 20.05
+	Dm
		1229016 Q9VWS1_DROME (233-441): 7.78e-49: 171: 15.91		Q8MSB1_DROME (1-390): 6.19e-103: 311: 23.21
+	Sc
		774570 VID30_YEAST (116-602): 2.54e-96: 317: 19.88		FYV10_YEAST (23-390): 1.01e-39: 149: 14.09
+	At
		1196564 Q94BS7_ARATH (40-442): 3.8e-103: 321: 22.01		GID8_ARATH (112-287): 5.77e-39: 141: 16.11
+	At
		95045 Q94BS7_ARATH (40-442): 3.8e-103: 321: 22.01		F4HTG9_ARATH (145-287): 4.78e-27: 107: 14.97