HitPredict

Interactor 1: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Interactor 2: PINK1 (Q9BXM7)
Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)
Gene: PINK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31300519
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Pkinase
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1025 Hs			1 581
+	Hs
		724998 MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		725236 MYH10_HUMAN (534-1014): 3.94e-16: 85.9: 9.18		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		1068650 PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		568704 PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51		KAPCA_HUMAN (173-567): 1.06e-110: 336: 13.89
+	Hs
		568798 PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24		KAPCA_HUMAN (173-567): 1.06e-110: 336: 13.89
+	Hs
		681696 MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66		AKT1_HUMAN (115-573): 2.58e-118: 360: 12.89
+	Hs
		1071703 PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24		KS6A2_HUMAN (197-576): 4.99e-92: 300: 15.42
+	Rn
		506743 ROCK2_RAT (502-969): 4.64e-41: 166: 18.71		KCC2A_RAT (221-538): 4.46e-82: 266: 20.62
+	Hs
		568567 MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66		KAPCA_HUMAN (173-567): 1.06e-110: 336: 13.89
+	Hs
		568568 MYH10_HUMAN (534-1014): 3.94e-16: 85.9: 9.18		KAPCA_HUMAN (173-567): 1.06e-110: 336: 13.89
+	Hs
		1334862 PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24		KCC2A_HUMAN (221-538): 5.11e-82: 266: 20.62
+	Hs
		254459 ROCK2_HUMAN (446-1018): 6.09e-17: 88.7: 11.81		KS6A3_HUMAN (154-555): 2.08e-92: 301: 16.59