HitPredict

Interactor 1: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Interactor 2: MEP50 (Q9BQA1)
Methylosome protein WDR77 (Androgen receptor cofactor p44) (Methylosome protein 50) (MEP-50) (WD repeat-containing protein 77) (p44/Mep50)
Gene: WDR77

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28977470
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~WD40
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1025 Hs			1 342
+	Hs
		1167395 MPRIP_HUMAN (1-1025): 9.29e-127: 412: 100.00		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		1309278 TARA_HUMAN (231-985): 1.44e-51: 201: 35.57		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Hs
		793015 DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61		LIS1_HUMAN (62-339): 9.49e-75: 238: 16.72
+	Hs
		1153353 PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Hs
		725233 MYH10_HUMAN (534-1014): 3.94e-16: 85.9: 9.18		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Hs
		1153322 PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		148462 CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42		COPB2_HUMAN (54-331): 3.17e-47: 172: 18.38
+	Hs
		725564 PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24		COPB2_HUMAN (54-331): 3.17e-47: 172: 18.38
+	Hs
		1240465 PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24		POC1A_HUMAN (201-341): 1.98e-27: 112: 18.31
+	Hs
		1153371 PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51		TBL1R_HUMAN (206-337): 3.38e-19: 90.1: 13.01
+	Hs
		903302 PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		724952 MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		148858 CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42		TAF5_HUMAN (178-328): 1.2e-21: 98: 18.42
+	Hs
		725215 MYH10_HUMAN (534-1014): 3.94e-16: 85.9: 9.18		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		148610 CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		1068625 PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		148157 CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42		PRP4_HUMAN (253-341): 3.86e-10: 62.8: 13.40
+	Hs
		728492 MYH11_HUMAN (124-786): 1.25e-12: 74.7: 11.57		POC1A_HUMAN (201-341): 1.98e-27: 112: 18.31
+	Hs
		903240 PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		255308 HIP1R_HUMAN (626-929): 1.25e-09: 64.5: 19.56		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79