Interactor 1: Q6XD99 (Q6XD99)
Spectrin beta chain
Gene: Sptbn1

Interactor 2: ACTN1 (Q9Z1P2)
Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin cross-linking protein) (Non-muscle alpha-actinin-1)
Gene: ACTN1

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 11274145
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CH~CH, CH~EFhand_Ca_insen, CH~Spectrin, EFhand_Ca_insen~Spectrin, Spectrin~Spectrin
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0030036 - actin cytoskeleton organization
GO:0030054 - cell junction
and 4 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 2358
Rn

1 892
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs
+ Ce
+ Ce
+ Ce
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024