Protein: SF3B5
Splicing factor 3B subunit 5 (SF3b5) (Pre-mRNA-splicing factor SF3b 10 kDa subunit)

Gene: SF3B5
Organism: Homo sapiens
Interactions: 109
UniProt ID: Q9BWJ5

Gene Ontology (top 5):
GO:0000124 - SAGA complex
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1073136

SF3B3
Splicing factor 3B subunit 3

5

1

Small-scale

0.912

High

1186262

PHF5A
PHD finger-like domain-containing protein 5A

3

1

High-throughput

0.861

High

453899

RU2A
U2 small nuclear ribonucleoprotein A'

5

1

High-throughput

0.718

High

1034393

SF3B2
Splicing factor 3B subunit 2

1

1

High-throughput

0.691

High

268846

SF3B1
Splicing factor 3B subunit 1

4

1

Small-scale

0.686

High

1073724

SF3A2
Splicing factor 3A subunit 2

4

1

Small-scale

0.686

High

1290966

CCD97
Coiled-coil domain-containing protein 97

3

1

High-throughput

0.675

High

1314751

SF3B6
Splicing factor 3B subunit 6

3

3

Small-scale

0.660

High

1198574

TAD2B
Transcriptional adapter 2-beta

3

1

High-throughput

0.656

High

441361

RU2B
U2 small nuclear ribonucleoprotein B''

2

2

High-throughput

0.628

High

539135

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

2

2

High-throughput

0.628

High

911735

RUXE
Small nuclear ribonucleoprotein E

2

1

High-throughput

0.628

High

911954

RUXF
Small nuclear ribonucleoprotein F

2

2

High-throughput

0.628

High

266501

SUPT3
Transcription initiation protein SPT3 homolog

2

1

High-throughput

0.611

High

267693

TADA3
Transcriptional adapter 3

2

1

High-throughput

0.611

High

1018866

SF3A3
Splicing factor 3A subunit 3

2

1

High-throughput

0.611

High

1074222

SF3A1
Splicing factor 3A subunit 1

2

1

High-throughput

0.611

High

1243309

SP20H
Transcription factor SPT20 homolog

2

1

High-throughput

0.611

High

1271447

KAT2A
Histone acetyltransferase KAT2A

2

2

High-throughput

0.611

High

1285669

TADA1
Transcriptional adapter 1

2

1

High-throughput

0.611

High

1290293

SGF29
SAGA-associated factor 29

2

1

High-throughput

0.611

High

1314747

PP4R2
Serine/threonine-protein phosphatase 4 regulatory subunit 2

2

0

High-throughput

0.608

High

370351

ESR1
Estrogen receptor

2

0

High-throughput

0.547

High

968214

OCRL
Inositol polyphosphate 5-phosphatase OCRL

2

0

High-throughput

0.547

High

267791

TAF5L
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L

1

2

High-throughput

0.536

High

801351

KI67
Proliferation marker protein Ki-67

1

1

High-throughput

0.536

High

891001

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

1

1

High-throughput

0.536

High

912104

RUXG
Small nuclear ribonucleoprotein G

1

6

High-throughput

0.536

High

912371

SMD1
Small nuclear ribonucleoprotein Sm D1

1

3

High-throughput

0.536

High

912554

SMD2
Small nuclear ribonucleoprotein Sm D2

1

1

High-throughput

0.536

High

928012

RSMN
Small nuclear ribonucleoprotein-associated protein N

1

3

High-throughput

0.536

High

1054558

RBM39
RNA-binding protein 39

1

2

High-throughput

0.536

High

1073634

SF3B4
Splicing factor 3B subunit 4

1

2

High-throughput

0.536

High

1082081

TAF12
Transcription initiation factor TFIID subunit 12

1

1

High-throughput

0.536

High

1083697

TAF9
Transcription initiation factor TFIID subunit 9

1

2

High-throughput

0.536

High

1201644

ZCH18
Zinc finger CCCH domain-containing protein 18

1

1

High-throughput

0.536

High

1204692

DDX42
ATP-dependent RNA helicase DDX42

1

1

High-throughput

0.536

High

1271493

KAT2B
Histone acetyltransferase KAT2B

1

2

High-throughput

0.536

High

1314740

NADAP
Kanadaptin

1

1

High-throughput

0.536

High

1314742

SKI8
Superkiller complex protein 8

1

2

High-throughput

0.536

High

1314744

TAF9B
Transcription initiation factor TFIID subunit 9B

1

2

High-throughput

0.536

High

1314752

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.536

High

1205895

MF2L2
Probable guanine nucleotide exchange factor MCF2L2

2

1

High-throughput

0.521

High

278869

DNJC8
DnaJ homolog subfamily C member 8

1

0

High-throughput

0.513

High

297930

ST65G
STAGA complex 65 subunit gamma

1

0

High-throughput

0.513

High

445514

RSSA
Small ribosomal subunit protein uS2

1

0

High-throughput

0.513

High

550937

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.513

High

721341

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.513

High

822143

KC1A
Casein kinase I isoform alpha

1

0

High-throughput

0.513

High

851669

NEK4
Serine/threonine-protein kinase Nek4

1

0

High-throughput

0.513

High

1149934

KDM4D
Lysine-specific demethylase 4D

1

0

High-throughput

0.513

High

1153051

P4R3A
Serine/threonine-protein phosphatase 4 regulatory subunit 3A

1

0

High-throughput

0.513

High

1235194

KKCC1
Calcium/calmodulin-dependent protein kinase kinase 1

1

0

High-throughput

0.513

High

1302413

IWS1
Protein IWS1 homolog

1

0

High-throughput

0.513

High

1314749

SRPK3
SRSF protein kinase 3

1

0

High-throughput

0.513

High

1314753

TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

1

0

High-throughput

0.513

High

641921

U2AF2
Splicing factor U2AF 65 kDa subunit

1

1

Small-scale

0.501

High

476307

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

347789

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

379812

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

738013

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

1

High-throughput

0.479

High

909064

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

1062113

AT7L3
Ataxin-7-like protein 3

1

1

High-throughput

0.479

High

1198272

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

1

1

Small-scale

0.479

High

1221702

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

1251011

SNIP1
Smad nuclear-interacting protein 1

1

1

High-throughput

0.479

High

125693

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

High-throughput

0.458

High

298774

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

325877

LATS1
Serine/threonine-protein kinase LATS1

1

0

High-throughput

0.458

High

374812

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

442456

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

570030

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

798994

GATA4
Transcription factor GATA-4

1

0

High-throughput

0.458

High

824349

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

917865

H4
Histone H4

1

0

High-throughput

0.458

High

935194

H31
Histone H3.1

1

0

High-throughput

0.458

High

1022190

NFX1
Transcriptional repressor NF-X1

1

0

High-throughput

0.458

High

1064678

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1116520

LARP7
La-related protein 7

1

0

High-throughput

0.458

High

1184312

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

1188811

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1270685

REQU
Zinc finger protein ubi-d4

1

0

High-throughput

0.458

High

1281362

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.458

High

1314741

API5
Apoptosis inhibitor 5

1

0

High-throughput

0.458

High

1314745

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

1314746

SMC4
Structural maintenance of chromosomes protein 4

1

0

High-throughput

0.458

High

1314748

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1314750

SRRM2
Serine/arginine repetitive matrix protein 2

1

0

High-throughput

0.458

High

302692

ARHGF
Rho guanine nucleotide exchange factor 15

1

3

High-throughput

0.437

High

548748

VAV
Proto-oncogene vav

1

2

High-throughput

0.437

High

957993

FGD1
FYVE, RhoGEF and PH domain-containing protein 1

1

2

High-throughput

0.437

High

1146803

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.437

High

1235265

NGEF
Ephexin-1

1

3

High-throughput

0.437

High

195536

DHX15
ATP-dependent RNA helicase DHX15

1

0

High-throughput

0.426

High

321189

PTBP3
Polypyrimidine tract-binding protein 3

1

0

High-throughput

0.426

High

1075741

SF01
Splicing factor 1

1

0

High-throughput

0.426

High

1124612

ODFP2
Outer dense fiber protein 2

1

0

High-throughput

0.426

High

1161725

TTC33
Tetratricopeptide repeat protein 33

2

0

High-throughput

0.318

High

276605

TPC6A
Trafficking protein particle complex subunit 6A

2

0

High-throughput

0.316

High

1291255

STALP
AMSH-like protease

2

0

High-throughput

0.316

High

259467

NIPS2
Protein NipSnap homolog 2

1

0

High-throughput

0.279

Low

1134043

AT7L2
Ataxin-7-like protein 2

1

0

High-throughput

0.279

Low

1238034

GPT11
G patch domain-containing protein 11

1

0

High-throughput

0.279

Low

297673

RHBT1
Rho-related BTB domain-containing protein 1

1

0

High-throughput

0.249

Low

932360

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.249

Low

1101584

RHG31
Rho GTPase-activating protein 31

1

0

High-throughput

0.249

Low

1314743

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1130543

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.232

Low

1241603

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024