HitPredict

Interactor 1: LMTK1 (Q6ZMQ8)
Serine/threonine-protein kinase LMTK1 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (Lemur tyrosine kinase 1) (p35-binding protein) (p35BP)
Gene: AATK

Interactor 2: GCC2 (Q8IWJ2)
GRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) (GCC185) (CLL-associated antigen KW-11) (CTCL tumor antigen se1-1) (Ran-binding protein 2-like 4) (RanBP2L4) (Renal carcinoma antigen NY-REN-53)
Gene: GCC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1374 Hs			1 1684
+	Hs
		411785 LCK_HUMAN (98-410): 1.51e-107: 352: 24.20		GCC2_HUMAN (1-1684): 8.38e-119: 415: 100.00
+	Mm
		222845 ACK1_MOUSE (55-976): 4.88e-124: 413: 20.25		MYH10_MOUSE (697-1684): 7.74e-42: 171: 9.88
+	Mm
		222875 ACK1_MOUSE (55-976): 4.88e-124: 413: 20.25		MYH9_MOUSE (1-933): 3.94e-38: 159: 11.75
+	Hs
		508011 FGFR1_HUMAN (28-460): 6.26e-120: 396: 21.00		PLEC_HUMAN (255-1682): 1.43e-31: 138: 10.06
+	Hs
		411707 LCK_HUMAN (98-410): 1.51e-107: 352: 24.20		GOGA4_HUMAN (1-1028): 1.78e-31: 137: 12.68
+	Hs
		665375 EPHA3_HUMAN (12-404): 1.11e-104: 358: 23.74		MYH9_HUMAN (1-734): 4.96e-29: 129: 10.41
+	Hs
		433620 LYN_HUMAN (109-410): 9.62e-106: 347: 24.75		MYH9_HUMAN (1-734): 4.96e-29: 129: 10.41
+	Mm
		222882 ACK1_MOUSE (55-976): 4.88e-124: 413: 20.25		MY18A_MOUSE (602-1343): 8.92e-09: 62.8: 19.77
+	Hs
		412058 FYN_HUMAN (104-408): 1.36e-104: 344: 30.07		MYH9_HUMAN (1-734): 4.96e-29: 129: 10.41
+	Hs
		609584 FGFR3_HUMAN (29-448): 5.82e-123: 403: 23.42		DAPLE_HUMAN (582-1406): 5.94e-09: 63.5: 20.77
+	Hs
		411724 LCK_HUMAN (98-410): 1.51e-107: 352: 24.20		GOGB1_HUMAN (1285-1677): 1.11e-09: 66.1: 12.44
+	Hs
		434048 LYN_HUMAN (109-410): 9.62e-106: 347: 24.75		DAPLE_HUMAN (582-1406): 5.94e-09: 63.5: 20.77
+	Hs
		384385 NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77		MYH10_HUMAN (697-1684): 5.34e-42: 171: 9.78
+	Hs
		725268 ALK_HUMAN (109-386): 2.69e-32: 139: 32.99		MYH10_HUMAN (697-1684): 5.34e-42: 171: 9.78
+	Hs
		384856 NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77		NUMA1_HUMAN (597-1673): 6.68e-36: 151: 10.82
+	Hs
		384384 NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77		MYH9_HUMAN (1-734): 4.96e-29: 129: 10.41
+	Hs
		725069 ALK_HUMAN (109-386): 2.69e-32: 139: 32.99		MYH9_HUMAN (1-734): 4.96e-29: 129: 10.41
+	Hs
		828639 ALK_HUMAN (109-386): 2.69e-32: 139: 32.99		CENPF_HUMAN (1-571): 7.48e-20: 99.6: 10.67
+	Hs
		384113 NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77		LAMB1_HUMAN (937-1308): 8.11e-10: 66.2: 21.93