Protein: EMC3
ER membrane protein complex subunit 3 (Transmembrane protein 111)

Gene: EMC3
Organism: Homo sapiens
Interactions: 117
UniProt ID: Q9P0I2

Gene Ontology (top 5):
GO:0005789 - endoplasmic reticulum membrane
GO:0016020 - membrane
GO:0034975 - protein folding in endoplasmic reticulum
GO:0045050 - protein insertion into ER membrane by stop-transfer membrane-anchor sequence
GO:0071816 - tail-anchored membrane protein insertion into ER membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1062697

EMC2
ER membrane protein complex subunit 2

8

1

Small-scale

0.970

High

1237018

EMC1
ER membrane protein complex subunit 1

5

2

High-throughput

0.932

High

1126693

EMC4
ER membrane protein complex subunit 4

4

2

High-throughput

0.909

High

1313581

EMC6
ER membrane protein complex subunit 6

2

0

High-throughput

0.736

High

1233981

EMC5
ER membrane protein complex subunit 5

6

0

High-throughput

0.707

High

1349566

EMC9
ER membrane protein complex subunit 9

4

2

High-throughput

0.704

High

202991

EMC8
ER membrane protein complex subunit 8

4

2

High-throughput

0.697

High

1137501

EMC10
ER membrane protein complex subunit 10

4

0

High-throughput

0.674

High

1342536

EMC7
Endoplasmic reticulum membrane protein complex subunit 7

4

0

High-throughput

0.674

High

1349563

TMCO1
Calcium load-activated calcium channel

1

0

High-throughput

0.656

High

1023446

TRDN
Triadin

2

0

High-throughput

0.602

High

654857

CALX
Calnexin

2

0

High-throughput

0.585

High

1240815

RN149
E3 ubiquitin-protein ligase RNF149

2

0

Small-scale

0.559

High

763121

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

1

High-throughput

0.536

High

868055

VMAT1
Chromaffin granule amine transporter

1

1

High-throughput

0.536

High

134683

NPT3
Sodium-dependent phosphate transport protein 3

1

0

High-throughput

0.513

High

149761

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.513

High

216625

S28A2
Sodium/nucleoside cotransporter 2

1

0

High-throughput

0.513

High

390585

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.513

High

883885

TMM33
Transmembrane protein 33

1

0

High-throughput

0.513

High

890475

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.513

High

1103582

S4A8
Electroneutral sodium bicarbonate exchanger 1

1

0

High-throughput

0.513

High

1229938

D106A
Beta-defensin 106

1

0

High-throughput

0.513

High

1235977

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

1

0

High-throughput

0.513

High

1240056

UBAC2
Ubiquitin-associated domain-containing protein 2

1

0

High-throughput

0.513

High

1283311

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

1326105

DERL2
Derlin-2

1

0

High-throughput

0.513

High

1349557

VAPA
Vesicle-associated membrane protein-associated protein A

1

0

High-throughput

0.513

High

1349561

FBX2
F-box only protein 2

1

1

High-throughput

0.489

High

48544

ESYT2
Extended synaptotagmin-2

1

1

High-throughput

0.479

High

272740

OFD1
Centriole and centriolar satellite protein OFD1

1

1

High-throughput

0.479

High

436548

RHOC
Rho-related GTP-binding protein RhoC

1

6

High-throughput

0.479

High

545666

RAC2
Ras-related C3 botulinum toxin substrate 2

1

6

High-throughput

0.479

High

892641

RAC3
Ras-related C3 botulinum toxin substrate 3

1

6

High-throughput

0.479

High

894527

CDC42
Cell division control protein 42 homolog

1

6

High-throughput

0.479

High

900989

RHOA
Transforming protein RhoA

1

7

High-throughput

0.479

High

925680

RAC1
Ras-related C3 botulinum toxin substrate 1

1

6

High-throughput

0.479

High

951416

RHOG
Rho-related GTP-binding protein RhoG

1

6

High-throughput

0.479

High

1101979

TECT1
Tectonic-1

1

2

High-throughput

0.479

High

1220695

MIRO2
Mitochondrial Rho GTPase 2

1

9

High-throughput

0.479

High

1296098

DNJC1
DnaJ homolog subfamily C member 1

1

3

High-throughput

0.479

High

1311434

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.479

High

1328875

DJC25
DnaJ homolog subfamily C member 25

1

2

High-throughput

0.479

High

1345079

TMPS4
Transmembrane protease serine 4

1

2

High-throughput

0.479

High

1349559

SEC63
Translocation protein SEC63 homolog

1

1

High-throughput

0.479

High

1349562

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.479

High

1349565

DJC16
DnaJ homolog subfamily C member 16

1

1

High-throughput

0.479

High

315222

CNEP1
CTD nuclear envelope phosphatase 1

1

0

High-throughput

0.458

High

339060

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

476487

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.458

High

879858

TPTE
Putative tyrosine-protein phosphatase TPTE

1

0

High-throughput

0.458

High

1051487

DCTN1
Dynactin subunit 1

1

0

High-throughput

0.458

High

1053234

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

0

High-throughput

0.458

High

1064789

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1126139

MKS3
Meckelin

1

0

High-throughput

0.458

High

1166017

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1218530

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.458

High

1234033

DJC22
DnaJ homolog subfamily C member 22

1

0

High-throughput

0.458

High

1243423

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.458

High

1255710

RBCC1
RB1-inducible coiled-coil protein 1

1

0

High-throughput

0.458

High

1300164

TM237
Transmembrane protein 237

1

0

High-throughput

0.458

High

1318314

EDEM3
ER degradation-enhancing alpha-mannosidase-like protein 3

1

0

Small-scale

0.458

High

1336427

SDF2L
Stromal cell-derived factor 2-like protein 1

1

0

High-throughput

0.458

High

1344452

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.458

High

1349558

TM216
Transmembrane protein 216

1

0

High-throughput

0.458

High

1349567

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.458

High

120682

RHOD
Rho-related GTP-binding protein RhoD

1

8

High-throughput

0.437

High

178020

TMPS2
Transmembrane protease serine 2

1

2

High-throughput

0.437

High

852654

RND2
Rho-related GTP-binding protein RhoN

1

8

High-throughput

0.437

High

1076792

RHOH
Rho-related GTP-binding protein RhoH

1

7

High-throughput

0.437

High

1156738

TECT3
Tectonic-3

1

2

High-throughput

0.437

High

1198205

TM11B
Transmembrane protease serine 11B

1

2

High-throughput

0.437

High

1263922

CLC4D
C-type lectin domain family 4 member D

1

1

High-throughput

0.437

High

1292889

TECT2
Tectonic-2

1

2

High-throughput

0.437

High

1335354

RHOF
Rho-related GTP-binding protein RhoF

1

8

High-throughput

0.437

High

1344582

FBX6
F-box only protein 6

1

1

High-throughput

0.437

High

1103100

ATG2A
Autophagy-related protein 2 homolog A

1

0

Small-scale

0.426

High

1241653

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.426

High

328177

SG1D1
Secretoglobin family 1D member 1

2

0

High-throughput

0.328

High

352812

IFN21
Interferon alpha-21

2

0

High-throughput

0.328

High

532005

PDIA4
Protein disulfide-isomerase A4

2

0

High-throughput

0.328

High

1165590

ENPP6
Glycerophosphocholine cholinephosphodiesterase ENPP6

2

0

High-throughput

0.318

High

1025000

MTAP
S-methyl-5'-thioadenosine phosphorylase

2

0

High-throughput

0.316

High

304767

NDUB6
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6

1

0

High-throughput

0.279

Low

351505

GON1
Progonadoliberin-1

1

0

High-throughput

0.279

Low

361620

APOA2
Apolipoprotein A-II

1

0

High-throughput

0.279

Low

483504

SAA1
Serum amyloid A-1 protein

1

0

High-throughput

0.279

Low

723920

SCN4A
Sodium channel protein type 4 subunit alpha

1

0

High-throughput

0.279

Low

873494

P5CS
Delta-1-pyrroline-5-carboxylate synthase

1

0

High-throughput

0.279

Low

1067638

P2RY6
P2Y purinoceptor 6

1

0

High-throughput

0.279

Low

1079702

ADIPO
Adiponectin

1

0

High-throughput

0.279

Low

1127761

PLAC9
Placenta-specific protein 9

1

0

High-throughput

0.279

Low

1232369

TAFA2
Chemokine-like protein TAFA-2

1

0

High-throughput

0.279

Low

1296627

LCFC1
Sperm-egg fusion protein LLCFC1

1

0

High-throughput

0.279

Low

1315959

MAK16
Protein MAK16 homolog

1

0

High-throughput

0.279

Low

1349560

UBQL2
Ubiquilin-2

1

0

High-throughput

0.279

Low

206092

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

214400

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.249

Low

553926

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

573950

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.249

Low

652463

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

721645

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

845304

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.249

Low

909249

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

941524

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1050285

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

0

High-throughput

0.249

Low

1086835

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low

1147666

FTM
Protein fantom

1

0

High-throughput

0.249

Low

1172048

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1188966

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1203882

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1283966

S2546
Mitochondrial outer membrane protein SLC25A46

1

0

High-throughput

0.249

Low

1303192

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.249

Low

1328275

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.249

Low

1331493

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1346190

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

1349564

AT1B4
Protein ATP1B4

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024