HitPredict

Interactor 1: SGK1 (O00141)
Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1)
Gene: SGK1

Interactor 2: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	23314748
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Pkinase~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 431 Hs			1 685
+	Hs
		475390 AKT1_HUMAN (25-426): 4.84e-154: 446: 41.57		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		475450 KPCI_HUMAN (4-426): 7.24e-151: 442: 34.56		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		408535 KPCB_HUMAN (27-430): 4.08e-146: 433: 37.53		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		475653 KPCZ_HUMAN (6-426): 2.47e-146: 430: 36.51		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		475314 KPCA_HUMAN (27-430): 1.24e-144: 429: 37.32		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		475345 KS6B1_HUMAN (91-429): 1.64e-145: 426: 45.35		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		923962 KPCE_HUMAN (6-423): 6.92e-151: 447: 33.84		RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00
+	Hs
		681773 AKT1_HUMAN (25-426): 4.84e-154: 446: 41.57		RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00
+	Rn
		448410 KPCD_RAT (6-431): 1.24e-152: 449: 35.36		UBC_RAT (1-108): 1.27e-29: 127: 90.74
+	Rn
		448416 KPCE_RAT (6-423): 7.78e-149: 441: 34.05		UBC_RAT (1-108): 1.27e-29: 127: 90.74
+	Mm
		476830 KPCI_MOUSE (6-426): 1.36e-148: 436: 34.72		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Hs
		474936 AKT2_HUMAN (25-426): 1.53e-155: 450: 40.52		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70
+	Rn
		934619 KPCB_RAT (27-430): 1.19e-145: 431: 37.53		UBC_RAT (1-108): 1.27e-29: 127: 90.74
+	Hs
		474935 AKT1_HUMAN (25-426): 4.84e-154: 446: 41.57		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70
+	Hs
		408534 KPCB_HUMAN (27-430): 4.08e-146: 433: 37.53		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70