Protein: COG4
Conserved oligomeric Golgi complex subunit 4 (COG complex subunit 4) (Component of oligomeric Golgi complex 4)

Gene: COG4
Organism: Homo sapiens
Interactions: 116
UniProt ID: Q9H9E3

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0000301 - retrograde transport, vesicle recycling within Golgi
GO:0005829 - cytosol
GO:0006890 - retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
GO:0007030 - Golgi organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1394750

COG3
Conserved oligomeric Golgi complex subunit 3

5

1

Small-scale

0.712

High

1437029

COG4
Conserved oligomeric Golgi complex subunit 4

1

1

Small-scale

0.692

High

1437043

COG6
Conserved oligomeric Golgi complex subunit 6

3

1

Small-scale

0.671

High

1131899

COG2
Conserved oligomeric Golgi complex subunit 2

3

1

Small-scale

0.670

High

1437040

COG5
Conserved oligomeric Golgi complex subunit 5

3

0

Small-scale

0.652

High

1013540

COG7
Conserved oligomeric Golgi complex subunit 7

3

0

Small-scale

0.642

High

1356159

COG1
Conserved oligomeric Golgi complex subunit 1

2

0

Small-scale

0.612

High

1394322

VSIG2
V-set and immunoglobulin domain-containing protein 2

3

1

High-throughput

0.609

High

250338

VINEX
Vinexin

2

1

High-throughput

0.606

High

1293909

VSIG1
V-set and immunoglobulin domain-containing protein 1

3

1

High-throughput

0.604

High

969059

PRS8
26S proteasome regulatory subunit 8

2

0

High-throughput

0.602

High

1153507

RAB30
Ras-related protein Rab-30

2

0

High-throughput

0.602

High

1437033

COMD8
COMM domain-containing protein 8

2

0

High-throughput

0.602

High

1358368

SCFD1
Sec1 family domain-containing protein 1

1

1

Small-scale

0.597

High

262312

SCN2B
Sodium channel regulatory subunit beta-2

3

2

High-throughput

0.593

High

155806

TXND9
Thioredoxin domain-containing protein 9

2

0

High-throughput

0.580

High

681034

PSA1
Proteasome subunit alpha type-1

2

0

High-throughput

0.580

High

1410257

F110A
Protein FAM110A

2

0

High-throughput

0.580

High

1437042

SYFA
Phenylalanine--tRNA ligase alpha subunit

2

0

High-throughput

0.580

High

770921

OPRM
Mu-type opioid receptor

2

2

High-throughput

0.574

High

1437036

PD1L1
Programmed cell death 1 ligand 1

2

1

High-throughput

0.558

High

638525

FPR1
fMet-Leu-Phe receptor

2

3

High-throughput

0.549

High

771236

APJ
Apelin receptor

2

2

High-throughput

0.549

High

835393

VIPR2
Vasoactive intestinal polypeptide receptor 2

2

1

High-throughput

0.549

High

1101665

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

2

4

High-throughput

0.549

High

1437045

NPTN
Neuroplastin

2

1

High-throughput

0.549

High

1115442

CUL4B
Cullin-4B

1

1

High-throughput

0.536

High

1436632

TRI45
E3 ubiquitin-protein ligase TRIM45

1

1

High-throughput

0.536

High

668718

APC
Adenomatous polyposis coli protein

1

0

High-throughput

0.518

High

874004

NRIP1
Nuclear receptor-interacting protein 1

1

0

High-throughput

0.518

High

923637

TTC3
E3 ubiquitin-protein ligase TTC3

1

0

High-throughput

0.518

High

1154172

ITSN1
Intersectin-1

1

0

High-throughput

0.518

High

1361839

RSPH1
Radial spoke head 1 homolog

1

0

High-throughput

0.518

High

1110090

HDAC1
Histone deacetylase 1

1

0

High-throughput

0.513

High

1406235

CHP1
Calcineurin B homologous protein 1

1

0

High-throughput

0.513

High

1430958

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.513

High

182777

GP182
G-protein coupled receptor 182

1

4

High-throughput

0.489

High

438104

GLPB
Glycophorin-B

1

1

High-throughput

0.489

High

466971

ACM4
Muscarinic acetylcholine receptor M4

1

1

High-throughput

0.489

High

868021

GLR
Glucagon receptor

1

1

High-throughput

0.489

High

879818

NPY2R
Neuropeptide Y receptor type 2

1

2

High-throughput

0.489

High

936126

PAR2
Proteinase-activated receptor 2

1

5

High-throughput

0.489

High

1291900

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

5

High-throughput

0.489

High

1437044

GPR45
Probable G-protein coupled receptor 45

1

1

High-throughput

0.489

High

1247984

ANR11
Ankyrin repeat domain-containing protein 11

1

1

High-throughput

0.481

High

278967

PEX14
Peroxisomal membrane protein PEX14

1

2

High-throughput

0.479

High

323569

TRI37
E3 ubiquitin-protein ligase TRIM37

1

1

High-throughput

0.479

High

774631

BASI
Basigin

1

2

High-throughput

0.479

High

901581

RAB7A
Ras-related protein Rab-7a

1

1

High-throughput

0.479

High

902078

RAB9A
Ras-related protein Rab-9A

1

1

High-throughput

0.479

High

1097893

STX5
Syntaxin-5

1

1

Small-scale

0.479

High

1234621

P4R3A
Serine/threonine-protein phosphatase 4 regulatory subunit 3A

1

1

High-throughput

0.479

High

1437046

X5D778
Ankyrin repeat domain 11 isoform A

1

1

High-throughput

0.470

High

880966

MTR1B
Melatonin receptor type 1B

1

3

High-throughput

0.464

High

139991

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.458

High

291544

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.458

High

363874

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

437347

K2C8
Keratin, type II cytoskeletal 8

1

0

High-throughput

0.458

High

905155

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

935149

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

1041300

CAV1
Caveolin-1

1

0

High-throughput

0.458

High

1334936

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

1436313

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

388301

GLPA
Glycophorin-A

1

1

High-throughput

0.445

High

1398547

COG8
Conserved oligomeric Golgi complex subunit 8

1

1

Small-scale

0.445

High

1115069

CUL4A
Cullin-4A

1

1

High-throughput

0.437

High

1142670

PDK1
[Pyruvate dehydrogenase

1

1

High-throughput

0.437

High

1431750

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

2

High-throughput

0.437

High

839087

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

0

High-throughput

0.426

High

1227484

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.426

High

1334414

UXS1
UDP-glucuronic acid decarboxylase 1

1

0

High-throughput

0.426

High

1366245

LPAR1
Lysophosphatidic acid receptor 1

1

2

High-throughput

0.407

High

1359001

TEKT4
Tektin-4

3

0

High-throughput

0.347

High

1437039

CAH14
Carbonic anhydrase 14

3

0

High-throughput

0.347

High

1194669

CCD40
Coiled-coil domain-containing protein 40

2

0

High-throughput

0.328

High

1248495

TMCO3
Transmembrane and coiled-coil domain-containing protein 3

2

0

High-throughput

0.328

High

1276161

NUP54
Nucleoporin p54

2

0

High-throughput

0.328

High

1330743

SIGL1
SIGLEC family-like protein 1

2

0

High-throughput

0.328

High

1437037

TAP26
Thyroid transcription factor 1-associated protein 26

2

0

High-throughput

0.328

High

1417599

BEX2
Protein BEX2

2

0

High-throughput

0.316

High

1437038

CTNA3
Catenin alpha-3

2

0

High-throughput

0.316

High

50699

HACL2
2-hydroxyacyl-CoA lyase 2

2

0

High-throughput

0.313

High

683339

TNR5
Tumor necrosis factor receptor superfamily member 5

2

0

High-throughput

0.313

High

1437034

OCAD1
OCIA domain-containing protein 1

2

0

High-throughput

0.313

High

249201

DSCAM
Cell adhesion molecule DSCAM

1

0

High-throughput

0.282

High

914346

EFNA4
Ephrin-A4

1

0

High-throughput

0.279

Low

1178891

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.279

Low

1179861

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1291684

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.279

Low

1325921

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.279

Low

1327463

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

1

0

High-throughput

0.279

Low

1381398

MUL1
Mitochondrial ubiquitin ligase activator of NFKB 1

1

0

High-throughput

0.279

Low

1420845

SEM4C
Semaphorin-4C

1

0

High-throughput

0.279

Low

1430688

F234A
Protein FAM234A

1

0

High-throughput

0.279

Low

1437030

GTR9
Solute carrier family 2, facilitated glucose transporter member 9

1

0

High-throughput

0.279

Low

1137016

SEPT2
Septin-2

1

0

High-throughput

0.265

Low

327454

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.249

Low

412629

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

589719

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

696539

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

769207

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1233492

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.249

Low

1255584

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1322992

CXD3
Gap junction delta-3 protein

1

0

High-throughput

0.249

Low

1433920

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1437032

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

1437035

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.249

Low

1351590

MIPT3
TRAF3-interacting protein 1

1

0

High-throughput

0.238

Low

166418

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

0

High-throughput

0.232

Low

704081

5HT1E
5-hydroxytryptamine receptor 1E

1

0

High-throughput

0.232

Low

760775

CD68
Macrosialin

1

0

High-throughput

0.232

Low

1289152

OSTA
Organic solute transporter subunit alpha

1

0

High-throughput

0.232

Low

1412070

S39A3
Zinc transporter ZIP3

1

0

High-throughput

0.232

Low

1437031

S22AB
Solute carrier family 22 member 11

1

0

High-throughput

0.232

Low

1437041

XCT
Cystine/glutamate transporter

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025