HitPredict

Interactor 1: NFIL3 (Q21361)
Transcription factor atf-2 (cAMP-dependent transcription factor atf-2)
Gene: atf-2

Interactor 2: Q9NAE4 (Q9NAE4)
BZIP domain-containing protein
Gene: zip-7

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	23791784
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	bZIP_2~bZIP_2
Common GO terms	GO:0003700 - DNA-binding transcription factor activity
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 401 Ce			1 185
+	Ce
		195245 NFIL3_CAEEL (1-401): 0: 520: 100.00		O16213_CAEEL (91-183): 7.81e-24: 95.6: 35.48
+	Ce
		1170198 NFIL3_CAEEL (1-401): 0: 520: 100.00		CES2_CAEEL (88-166): 3.05e-23: 93.3: 37.98
+	Ce
		1170194 NFIL3_CAEEL (1-401): 0: 520: 100.00		CEBP2_CAEEL (88-169): 3.52e-18: 77.1: 24.39
+	Ce
		1170191 NFIL3_CAEEL (1-401): 0: 520: 100.00		NFIL3_CAEEL (101-176): 1.93e-11: 63.6: 36.84
+	Ce
		195248 O16213_CAEEL (50-154): 1.12e-33: 127: 32.46		Q9NAE4_CAEEL (1-185): 7.19e-46: 150: 100.00
+	Dm
		1217088 Q5U8V5_DROME (25-111): 5.31e-36: 134: 24.14		Q5U8V5_DROME (59-168): 2.7e-27: 105: 30.58
+	Dm
		1344925 Q8SZT1_DROME (25-111): 5.84e-33: 132: 24.14		Q8SZT1_DROME (59-168): 4.25e-25: 103: 30.58
+	Ce
		195241 O16213_CAEEL (50-154): 1.12e-33: 127: 32.46		O16213_CAEEL (91-183): 7.81e-24: 95.6: 35.48
+	Ce
		195247 O16213_CAEEL (50-154): 1.12e-33: 127: 32.46		CES2_CAEEL (88-166): 3.05e-23: 93.3: 37.98
+	Mb
		72501 A9UU10_MONBE (37-145): 1.62e-32: 126: 28.44		A9V4P8_MONBE (76-177): 1.04e-20: 90.6: 21.55
+	Mm
		1440903 TEF_MOUSE (25-106): 5.63e-30: 119: 23.17		TEF_MOUSE (65-169): 7.88e-24: 96.9: 27.59
+	Hs
		606691 TEF_HUMAN (25-106): 1.77e-30: 120: 23.17		CEBPB_HUMAN (69-175): 1.38e-22: 94.2: 23.15
+	Dm
		56569 A1ZAC2_DROME (10-112): 1.26e-32: 123: 25.71		A1ZAC2_DROME (91-177): 8.5e-22: 89.2: 37.93
+	Hs
		606828 NFIL3_HUMAN (4-127): 1.92e-28: 118: 33.33		CEBPB_HUMAN (69-175): 1.38e-22: 94.2: 23.15
+	Hs
		1158040 NFIL3_HUMAN (4-127): 1.92e-28: 118: 33.33		HLF_HUMAN (66-168): 1.64e-22: 93.4: 26.32
+	Hs
		886909 NFIL3_HUMAN (4-127): 1.92e-28: 118: 33.33		CEBPA_HUMAN (62-165): 3.19e-22: 93.4: 25.00
+	Mm
		1221963 TEF_MOUSE (25-106): 5.63e-30: 119: 23.17		DBP_MOUSE (66-173): 1.28e-20: 88.8: 30.25
+	Ce
		195246 O16213_CAEEL (50-154): 1.12e-33: 127: 32.46		CEBP2_CAEEL (88-169): 3.52e-18: 77.1: 24.39
+	Hs
		1160832 NFIL3_HUMAN (4-127): 1.92e-28: 118: 33.33		NFIL3_HUMAN (84-153): 1.06e-18: 84.4: 32.86