Protein: NFIL3
Nuclear factor interleukin-3-regulated protein (E4 promoter-binding protein 4) (Interleukin-3 promoter transcriptional activator) (Interleukin-3-binding protein 1) (Transcriptional activator NF-IL3A)

Gene: NFIL3
Organism: Homo sapiens
Interactions: 41
UniProt ID: Q16649

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

593120

CREB1
Cyclic AMP-responsive element-binding protein 1

3

9

High-throughput

0.866

High

1160832

NFIL3
Nuclear factor interleukin-3-regulated protein

3

16

Small-scale

0.845

High

617099

ATF1
Cyclic AMP-dependent transcription factor ATF-1

2

19

High-throughput

0.799

High

1160848

AMOL2
Angiomotin-like protein 2

4

6

High-throughput

0.703

High

230329

CREB3
Cyclic AMP-responsive element-binding protein 3

1

20

High-throughput

0.647

High

1157634

BATF
Basic leucine zipper transcriptional factor ATF-like

1

20

High-throughput

0.647

High

1158040

HLF
Hepatic leukemia factor

1

17

High-throughput

0.647

High

1160833

CR3L3
Cyclic AMP-responsive element-binding protein 3-like protein 3

1

20

High-throughput

0.647

High

606828

CEBPB
CCAAT/enhancer-binding protein beta

1

19

High-throughput

0.618

High

886909

CEBPA
CCAAT/enhancer-binding protein alpha

1

19

High-throughput

0.618

High

1160837

COP1
E3 ubiquitin-protein ligase COP1

3

14

High-throughput

0.609

High

775429

DDIT3
DNA damage-inducible transcript 3 protein

2

12

High-throughput

0.602

High

1160843

MCM9
DNA helicase MCM9

2

11

Small-scale

0.584

High

269215

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

1160839

GMCL1
Germ cell-less protein-like 1

2

0

High-throughput

0.580

High

1160836

STK40
Serine/threonine-protein kinase 40

2

9

High-throughput

0.574

High

1160838

PIHD2
PIH1 domain-containing protein 2

2

1

High-throughput

0.553

High

1116416

FHL1
Four and a half LIM domains protein 1

1

5

High-throughput

0.541

High

1160841

CBX8
Chromobox protein homolog 8

1

5

High-throughput

0.536

High

1090669

TRAF2
TNF receptor-associated factor 2

1

6

High-throughput

0.523

High

563833

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

193343

MAFG
Transcription factor MafG

1

13

High-throughput

0.501

High

325860

UBR5
E3 ubiquitin-protein ligase UBR5

1

4

Small-scale

0.501

High

1031901

NC2B
Protein Dr1

1

3

Small-scale

0.501

High

1160846

DNM3L
DNA

1

3

Small-scale

0.501

High

1160847

MAFF
Transcription factor MafF

1

13

High-throughput

0.501

High

1160849

SNX8
Sorting nexin-8

1

5

High-throughput

0.489

High

613058

EGR1
Early growth response protein 1

1

11

Small-scale

0.479

High

979737

H4
Histone H4

1

6

High-throughput

0.479

High

1104312

ORC1
Origin recognition complex subunit 1

1

1

Small-scale

0.479

High

1160834

NIPBL
Nipped-B-like protein

1

9

High-throughput

0.479

High

1160842

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

1

9

High-throughput

0.479

High

1160845

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

154989

BHE40
Class E basic helix-loop-helix protein 40

1

6

High-throughput

0.457

High

372151

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.445

High

1094903

TRAF3
TNF receptor-associated factor 3

1

7

High-throughput

0.407

High

303332

PDE9A
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

2

0

High-throughput

0.316

High

1160835

RINT1
RAD50-interacting protein 1

2

0

High-throughput

0.316

High

1160840

FUCO2
Plasma alpha-L-fucosidase

1

0

High-throughput

0.279

Low

1160844

DEC1
Deleted in esophageal cancer 1

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025