HitPredict

Interactor 1: PDLI1 (O00151)
PDZ and LIM domain protein 1 (C-terminal LIM domain protein 1) (Elfin) (LIM domain protein CLP-36)
Gene: PDLIM1

Interactor 2: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35987950, 35256949
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005737 - cytoplasm GO:0006979 - response to oxidative stress
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 329 Hs			1 465
+	Hs
		227365 SNTB2_HUMAN (6-278): 2.94e-25: 107: 12.72		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		227141 DLG4_HUMAN (1-87): 9.22e-20: 92.2: 25.53		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		226828 PAXI_HUMAN (253-315): 8.47e-13: 70.9: 22.22		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		228350 PDLI5_HUMAN (60-312): 1.59e-10: 64.1: 12.50		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		228800 PDLI7_HUMAN (88-312): 2.86e-09: 59.8: 13.12		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		1317087 PDLI7_HUMAN (88-312): 2.86e-09: 59.8: 13.12		HOIL1_HUMAN (12-448): 5.59e-68: 227: 16.36
+	Hs
		476212 PDLI2_HUMAN (5-316): 4.7e-40: 145: 29.53		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	Xl
		1186352 Q9DDK9_XENLA (241-315): 6.05e-14: 74.3: 18.67		Q7SY79_XENLA (1-149): 2.25e-49: 179: 19.33
+	Hs
		475714 SNTB2_HUMAN (6-278): 2.94e-25: 107: 12.72		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	Hs
		476201 PDLI5_HUMAN (60-312): 1.59e-10: 64.1: 12.50		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47