Protein: INT1
Integrator complex subunit 1 (Int1)

Gene: INT1, INTS1
Organism: Homo sapiens
Interactions: 164
UniProt ID: Q8N201

Gene Ontology (top 5):
GO:0001833 - inner cell mass cell proliferation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0007566 - embryo implantation
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

930921

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

5

3

Small-scale

0.714

High

672204

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

4

1

High-throughput

0.702

High

1231104

INT12
Integrator complex subunit 12

3

1

High-throughput

0.657

High

1231111

INT14
Integrator complex subunit 14

3

2

High-throughput

0.656

High

205656

TGON2
Trans-Golgi network integral membrane protein 2

3

0

High-throughput

0.638

High

369985

ESR1
Estrogen receptor

3

1

High-throughput

0.624

High

1160516

INT5
Integrator complex subunit 5

2

1

High-throughput

0.611

High

50187

HACL2
2-hydroxyacyl-CoA lyase 2

2

0

High-throughput

0.602

High

1231138

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

2

0

Small-scale

0.592

High

124008

SPT5H
Transcription elongation factor SPT5

2

0

High-throughput

0.585

High

676937

RPB2
DNA-directed RNA polymerase II subunit RPB2

2

0

High-throughput

0.585

High

798266

KI2S2
Killer cell immunoglobulin-like receptor 2DS2

2

0

High-throughput

0.585

High

455644

PARP1
Poly [ADP-ribose] polymerase 1

2

1

High-throughput

0.584

High

915238

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

2

3

High-throughput

0.584

High

1231133

INT6
Integrator complex subunit 6

2

2

Small-scale

0.584

High

723072

OPRM
Mu-type opioid receptor

2

5

High-throughput

0.574

High

723344

APJ
Apelin receptor

2

6

High-throughput

0.574

High

824723

NPY2R
Neuropeptide Y receptor type 2

2

5

High-throughput

0.574

High

1231126

INT13
Integrator complex subunit 13

2

1

Small-scale

0.571

High

553168

RFA2
Replication protein A 32 kDa subunit

2

0

High-throughput

0.559

High

651670

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

0

High-throughput

0.559

High

720901

RFA3
Replication protein A 14 kDa subunit

2

0

High-throughput

0.559

High

917581

H4
Histone H4

2

0

High-throughput

0.559

High

1231107

INT4
Integrator complex subunit 4

2

0

High-throughput

0.559

High

1231127

INT10
Integrator complex subunit 10

2

0

Small-scale

0.559

High

172111

GP182
G-protein coupled receptor 182

1

6

High-throughput

0.536

High

595551

GRAH
Granzyme H

1

1

High-throughput

0.536

High

598978

FPR1
fMet-Leu-Phe receptor

1

7

High-throughput

0.536

High

674049

V2R
Vasopressin V2 receptor

1

7

High-throughput

0.536

High

726310

BASI
Basigin

1

1

High-throughput

0.536

High

814275

GLR
Glucagon receptor

1

5

High-throughput

0.536

High

818244

SOX2
Transcription factor SOX-2

1

2

High-throughput

0.536

High

976348

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

1

4

High-throughput

0.536

High

996767

SSRP1
FACT complex subunit SSRP1

1

2

High-throughput

0.536

High

1224672

AGRG2
Adhesion G-protein coupled receptor G2

1

1

High-throughput

0.536

High

1231114

CML1
Chemerin-like receptor 1

1

7

High-throughput

0.536

High

196823

CYB5B
Cytochrome b5 type B

1

0

High-throughput

0.513

High

274264

STK16
Serine/threonine-protein kinase 16

1

0

High-throughput

0.513

High

283652

JTB
Protein JTB

1

0

High-throughput

0.513

High

321341

STR3N
STARD3 N-terminal-like protein

1

0

High-throughput

0.513

High

505436

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

0

High-throughput

0.513

High

583746

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.513

High

602202

DRD4
D(4) dopamine receptor

1

0

High-throughput

0.513

High

795371

SSRB
Translocon-associated protein subunit beta

1

0

High-throughput

0.513

High

864962

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.513

High

897569

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.513

High

957432

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.513

High

1039685

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.513

High

1202501

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.513

High

1231092

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.513

High

1231097

F174A
Membrane protein FAM174A

1

0

High-throughput

0.513

High

1231102

AQP3
Aquaporin-3

1

0

High-throughput

0.513

High

1231112

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.513

High

1231113

NPAS1
Neuronal PAS domain-containing protein 1

1

0

High-throughput

0.513

High

1231119

CXL16
C-X-C motif chemokine 16

1

0

High-throughput

0.513

High

1231128

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.513

High

1231132

CC018
Uncharacterized protein C3orf18

1

0

High-throughput

0.513

High

1231135

FZD10
Frizzled-10

1

0

High-throughput

0.513

High

1231131

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.493

High

126618

P2Y10
Putative P2Y purinoceptor 10

1

9

High-throughput

0.489

High

156876

FFAR1
Free fatty acid receptor 1

1

9

High-throughput

0.489

High

198114

MTLR
Motilin receptor

1

6

High-throughput

0.489

High

208462

OX2R
Orexin receptor type 2

1

5

High-throughput

0.489

High

380127

MAS
Proto-oncogene Mas

1

10

High-throughput

0.489

High

686330

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

4

High-throughput

0.489

High

706916

CD80
T-lymphocyte activation antigen CD80

1

1

High-throughput

0.489

High

781084

OPRX
Nociceptin receptor

1

4

High-throughput

0.489

High

782440

P2RY2
P2Y purinoceptor 2

1

9

High-throughput

0.489

High

783682

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

4

High-throughput

0.489

High

876155

PAR2
Proteinase-activated receptor 2

1

9

High-throughput

0.489

High

1031006

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

8

High-throughput

0.489

High

1202690

P2RY8
P2Y purinoceptor 8

1

10

High-throughput

0.489

High

1231096

GP150
Probable G-protein coupled receptor 150

1

6

High-throughput

0.489

High

1231098

PKR1
Prokineticin receptor 1

1

5

High-throughput

0.489

High

1231137

GPR55
G-protein coupled receptor 55

1

10

High-throughput

0.489

High

1231139

GPR45
Probable G-protein coupled receptor 45

1

3

High-throughput

0.489

High

1231140

NPTN
Neuroplastin

1

1

High-throughput

0.489

High

583521

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

Small-scale

0.479

High

268172

EED
Polycomb protein EED

1

1

High-throughput

0.479

High

672446

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

1

1

High-throughput

0.479

High

841810

CDK9
Cyclin-dependent kinase 9

1

1

High-throughput

0.479

High

906530

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

4

High-throughput

0.479

High

934973

H31
Histone H3.1

1

1

High-throughput

0.479

High

952463

H33
Histone H3.3

1

1

High-throughput

0.479

High

1127512

INT6L
Integrator complex subunit 6-like

1

2

High-throughput

0.479

High

1135513

INT11
Integrator complex subunit 11

1

3

High-throughput

0.479

High

1174176

UBP43
Ubiquitin carboxyl-terminal hydrolase 43

1

1

High-throughput

0.479

High

1231110

CIC
Protein capicua homolog

1

1

High-throughput

0.479

High

1231116

FACD2
Fanconi anemia group D2 protein

1

1

High-throughput

0.479

High

1231124

INT9
Integrator complex subunit 9

1

3

High-throughput

0.479

High

825718

MTR1B
Melatonin receptor type 1B

1

5

High-throughput

0.464

High

149041

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

228030

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

244659

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

385159

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

612995

TCEA1
Transcription elongation factor A protein 1

1

0

High-throughput

0.458

High

624957

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.458

High

742392

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

757682

IF4A3
Eukaryotic initiation factor 4A-III

1

0

High-throughput

0.458

High

824184

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

854329

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.458

High

877315

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

0

High-throughput

0.458

High

918516

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

941153

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1042015

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1051984

ELOA1
Elongin-A

1

0

Small-scale

0.458

High

1063488

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.458

High

1068445

CDK10
Cyclin-dependent kinase 10

1

0

High-throughput

0.458

High

1080113

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1140608

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.458

High

1148306

INT3
Integrator complex subunit 3

1

0

High-throughput

0.458

High

1175973

INT8
Integrator complex subunit 8

1

0

High-throughput

0.458

High

1188551

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1221332

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

1

0

High-throughput

0.458

High

1230870

ZN687
Zinc finger protein 687

1

0

High-throughput

0.458

High

1231101

SIA8A
Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase

1

0

High-throughput

0.458

High

1231105

MBD6
Methyl-CpG-binding domain protein 6

1

0

High-throughput

0.458

High

1231108

INT15
Integrator complex subunit 15

1

0

High-throughput

0.458

High

1231115

SOSB1
SOSS complex subunit B1

1

0

High-throughput

0.458

High

1231117

INT2
Integrator complex subunit 2

1

0

High-throughput

0.458

High

1231118

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

1231122

WDR76
WD repeat-containing protein 76

1

0

High-throughput

0.458

High

1231123

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

High-throughput

0.458

High

1231125

INT7
Integrator complex subunit 7

1

0

High-throughput

0.458

High

1231129

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1231134

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

0

High-throughput

0.458

High

1231136

SMC3
Structural maintenance of chromosomes protein 3

1

0

High-throughput

0.458

High

263440

DEAF1
Deformed epidermal autoregulatory factor 1 homolog

1

1

High-throughput

0.457

High

354504

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.426

High

893576

SEM1
26S proteasome complex subunit SEM1

1

0

High-throughput

0.426

High

949840

CBX1
Chromobox protein homolog 1

1

0

Small-scale

0.426

High

1203542

STING
Stimulator of interferon genes protein

1

0

Small-scale

0.426

High

1231093

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

848899

AL3A2
Aldehyde dehydrogenase family 3 member A2

3

0

High-throughput

0.347

High

258738

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

2

0

High-throughput

0.328

High

1231095

IQCF1
IQ domain-containing protein F1

2

0

High-throughput

0.318

High

217095

NKG2F
NKG2-F type II integral membrane protein

1

0

High-throughput

0.279

Low

271968

CTAG2
Cancer/testis antigen 2

1

0

High-throughput

0.279

Low

353075

IL2RA
Interleukin-2 receptor subunit alpha

1

0

High-throughput

0.279

Low

589131

TCO2
Transcobalamin-2

1

0

High-throughput

0.279

Low

702250

CD70
CD70 antigen

1

0

High-throughput

0.279

Low

856418

EFNA4
Ephrin-A4

1

0

High-throughput

0.279

Low

1056216

I13R2
Interleukin-13 receptor subunit alpha-2

1

0

High-throughput

0.279

Low

1166508

BTNL9
Butyrophilin-like protein 9

1

0

High-throughput

0.279

Low

1168181

T184A
Transmembrane protein 184A

1

0

High-throughput

0.279

Low

1191165

DHB13
17-beta-hydroxysteroid dehydrogenase 13

1

0

High-throughput

0.279

Low

1193267

B3GN8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8

1

0

High-throughput

0.279

Low

1203129

OSTM1
Osteopetrosis-associated transmembrane protein 1

1

0

High-throughput

0.279

Low

1231091

TM130
Transmembrane protein 130

1

0

High-throughput

0.279

Low

1231094

KTAP2
Keratinocyte-associated protein 2

1

0

High-throughput

0.279

Low

1231099

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

1231103

SKA1
Spindle and kinetochore-associated protein 1

1

0

High-throughput

0.279

Low

1231106

PLPR2
Phospholipid phosphatase-related protein type 2

1

0

High-throughput

0.279

Low

1231109

OPALI
Opalin

1

0

High-throughput

0.279

Low

1231130

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

100942

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

441752

CFAH
Complement factor H

1

0

Small-scale

0.249

Low

545491

RAC2
Ras-related C3 botulinum toxin substrate 2

1

0

High-throughput

0.249

Low

1030734

SLAF1
Signaling lymphocytic activation molecule

1

0

High-throughput

0.249

Low

1170783

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1173038

SEML
Putative protein SEM1, isoform 2

1

0

High-throughput

0.249

Low

1231120

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1231121

RPAP3
RNA polymerase II-associated protein 3

1

0

High-throughput

0.249

Low

1231100

CE192
Centrosomal protein of 192 kDa

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024