Protein: SPC24
Kinetochore protein Spc24 (hSpc24)

Gene: SPC24
Organism: Homo sapiens
Interactions: 81
UniProt ID: Q8NBT2

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0000940 - outer kinetochore
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1334230

SPC25
Kinetochore protein Spc25

11

2

Small-scale

0.978

High

164018

NDC80
Kinetochore protein NDC80 homolog

8

1

Small-scale

0.971

High

1334224

DSN1
Kinetochore-associated protein DSN1 homolog

7

1

High-throughput

0.967

High

1334220

NUF2
Kinetochore protein Nuf2

7

3

High-throughput

0.962

High

1334221

MIS12
Protein MIS12 homolog

9

1

Small-scale

0.754

High

329949

ZWINT
Outer kinetochore KNL1 complex subunit ZWINT

8

1

Small-scale

0.751

High

1334207

KNL1
Outer kinetochore KNL1 complex subunit KNL1

7

1

Small-scale

0.744

High

1240751

PMF1
Polyamine-modulated factor 1

5

1

High-throughput

0.718

High

1334216

NSL1
Kinetochore-associated protein NSL1 homolog

6

0

High-throughput

0.701

High

1334213

SGF29
SAGA-associated factor 29

3

0

High-throughput

0.638

High

1326631

KIF2B
Kinesin-like protein KIF2B

2

0

High-throughput

0.602

High

791026

TALDO
Transaldolase

2

0

High-throughput

0.585

High

445219

S10A6
Protein S100-A6

1

3

High-throughput

0.536

High

682548

S100P
Protein S100-P

1

3

High-throughput

0.536

High

686841

S10A4
Protein S100-A4

1

3

High-throughput

0.536

High

171516

S27A2
Long-chain fatty acid transport protein 2

1

0

High-throughput

0.513

High

302898

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

0

High-throughput

0.513

High

892596

DNLI3
DNA ligase 3

1

0

High-throughput

0.513

High

1210352

NU188
Nucleoporin NUP188

1

0

High-throughput

0.513

High

1311143

UBR2
E3 ubiquitin-protein ligase UBR2

1

0

High-throughput

0.513

High

1334205

SMG8
Nonsense-mediated mRNA decay factor SMG8

1

0

High-throughput

0.513

High

1334217

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.513

High

1334219

TRI56
E3 ubiquitin-protein ligase TRIM56

1

0

High-throughput

0.513

High

1334222

ASCC2
Activating signal cointegrator 1 complex subunit 2

1

0

High-throughput

0.513

High

224142

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

1

0

High-throughput

0.493

High

706222

S10A2
Protein S100-A2

1

3

High-throughput

0.489

High

422620

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

755600

TTK
Dual specificity protein kinase TTK

1

0

Small-scale

0.479

High

761770

HSP74
Heat shock 70 kDa protein 4

1

1

High-throughput

0.479

High

890753

PSN2
Presenilin-2

1

0

High-throughput

0.460

High

1311942

SKA3
Spindle and kinetochore-associated protein 3

1

0

Small-scale

0.460

High

1334209

SKA2
Spindle and kinetochore-associated protein 2

1

0

Small-scale

0.460

High

1334211

SKA1
SKA complex subunit 1

1

0

Small-scale

0.460

High

278901

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.458

High

290083

OFD1
Centriole and centriolar satellite protein OFD1

1

0

High-throughput

0.458

High

606918

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

613399

VINC
Vinculin

1

0

High-throughput

0.458

High

861690

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

0

Small-scale

0.458

High

934868

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

986573

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.458

High

1110658

DCTN2
Dynactin subunit 2

1

0

High-throughput

0.458

High

1113723

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1123721

DCTN1
Dynactin subunit 1

1

0

High-throughput

0.458

High

1143427

PCM1
Pericentriolar material 1 protein

1

0

High-throughput

0.458

High

1289458

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1322404

SPICE
Spindle and centriole-associated protein 1

1

0

High-throughput

0.458

High

1326271

NIN
Ninein

1

0

High-throughput

0.458

High

1334210

ASB11
Ankyrin repeat and SOCS box protein 11

1

0

High-throughput

0.458

High

1334212

CENPT
Centromere protein T

1

0

Small-scale

0.458

High

1334214

BICD1
Protein bicaudal D homolog 1

1

0

High-throughput

0.458

High

1334223

BOLA2
BolA-like protein 2

1

0

High-throughput

0.458

High

1334226

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1334228

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1334231

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.458

High

1334235

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.458

High

1334237

U3KQ54
HCG2044777

1

1

High-throughput

0.445

High

1135222

Q149M6
Exophilin 5

1

1

High-throughput

0.437

High

1334206

EXPH5
Exophilin-5

1

1

High-throughput

0.407

High

168873

PLD2
Phospholipase D2

4

0

High-throughput

0.360

High

50029

F170A
Protein FAM170A

3

0

High-throughput

0.347

High

1316839

ASPM
Abnormal spindle-like microcephaly-associated protein

3

0

High-throughput

0.347

High

1211432

CF141
Uncharacterized protein C6orf141

2

0

High-throughput

0.328

High

1334236

EMIL1
EMILIN-1

2

0

High-throughput

0.328

High

946166

MLF1
Myeloid leukemia factor 1

2

0

High-throughput

0.318

High

907166

SUOX
Sulfite oxidase, mitochondrial

2

0

High-throughput

0.316

High

1334233

WHRN
Whirlin

2

0

High-throughput

0.316

High

253867

TPST2
Protein-tyrosine sulfotransferase 2

1

0

High-throughput

0.279

Low

608305

EGLN
Endoglin

1

0

High-throughput

0.279

Low

914304

EFNA4
Ephrin-A4

1

0

High-throughput

0.279

Low

1186282

MA7D1
MAP7 domain-containing protein 1

1

0

High-throughput

0.279

Low

1334204

DYHC2
Cytoplasmic dynein 2 heavy chain 1

1

0

High-throughput

0.279

Low

1334218

NPAS1
Neuronal PAS domain-containing protein 1

1

0

High-throughput

0.279

Low

1334215

PLPR2
Phospholipid phosphatase-related protein type 2

1

0

High-throughput

0.249

Low

1334225

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1334227

AAMDC
Mth938 domain-containing protein

1

0

High-throughput

0.249

Low

1334229

ZFYV1
Zinc finger FYVE domain-containing protein 1

1

0

Small-scale

0.249

Low

1334232

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

0

High-throughput

0.249

Low

1334234

PURG
Purine-rich element-binding protein gamma

1

0

High-throughput

0.249

Low

211154

CTR4
Cationic amino acid transporter 4

1

0

High-throughput

0.232

Low

1312949

S35F2
Solute carrier family 35 member F2

1

0

High-throughput

0.232

Low

1334208

G6PT3
Glucose-6-phosphate exchanger SLC37A2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025