Protein: DSN1
Kinetochore-associated protein DSN1 homolog

Gene: DSN1
Organism: Homo sapiens
Interactions: 99
UniProt ID: Q9H410

Gene Ontology (top 5):
GO:0000444 - MIS12/MIND type complex
GO:0000776 - kinetochore
GO:0000922 - spindle pole
GO:0000940 - outer kinetochore
GO:0001650 - fibrillar center

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1240776

PMF1
Polyamine-modulated factor 1

8

1

Small-scale

0.971

High

1334224

SPC24
Kinetochore protein Spc24

7

1

High-throughput

0.967

High

1429539

MIS12
Protein MIS12 homolog

14

0

Small-scale

0.933

High

1394504

NSL1
Kinetochore-associated protein NSL1 homolog

13

0

Small-scale

0.931

High

1433045

SPC25
Kinetochore protein Spc25

6

0

High-throughput

0.900

High

853406

CBX5
Chromobox protein homolog 5

9

2

Small-scale

0.756

High

164091

NDC80
Kinetochore protein NDC80 homolog

6

1

High-throughput

0.735

High

329976

ZWINT
Outer kinetochore KNL1 complex subunit ZWINT

10

0

Small-scale

0.725

High

1339883

KNL1
Outer kinetochore KNL1 complex subunit KNL1

9

0

Small-scale

0.721

High

1097555

CBX3
Chromobox protein homolog 3

5

2

Small-scale

0.718

High

1419593

NUF2
Kinetochore protein Nuf2

7

0

High-throughput

0.717

High

786845

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

5

0

High-throughput

0.682

High

1014200

CBX1
Chromobox protein homolog 1

3

2

High-throughput

0.675

High

272752

BRE1B
E3 ubiquitin-protein ligase BRE1B

3

2

High-throughput

0.667

High

1217914

BRE1A
E3 ubiquitin-protein ligase BRE1A

3

2

High-throughput

0.667

High

1433046

SALL1
Sal-like protein 1

3

1

High-throughput

0.667

High

1347249

EXOC6
Exocyst complex component 6

4

0

High-throughput

0.661

High

137275

EXOC5
Exocyst complex component 5

3

0

High-throughput

0.638

High

298078

SPF27
Pre-mRNA-splicing factor SPF27

3

0

High-throughput

0.638

High

904381

BRCA2
Breast cancer type 2 susceptibility protein

3

0

High-throughput

0.638

High

946200

MLF1
Myeloid leukemia factor 1

3

0

High-throughput

0.638

High

1123114

FHL2
Four and a half LIM domains protein 2

3

0

High-throughput

0.638

High

1433051

EXOC7
Exocyst complex component 7

3

0

High-throughput

0.638

High

1041855

CENPC
Centromere protein C

2

1

High-throughput

0.628

High

1433052

SGT1
Protein SGT1 homolog

2

0

Small-scale

0.619

High

169750

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

1

High-throughput

0.606

High

1326641

KIF2B
Kinesin-like protein KIF2B

2

0

High-throughput

0.602

High

186806

P73
Tumor protein p73

2

0

High-throughput

0.585

High

1094814

CAF1B
Chromatin assembly factor 1 subunit B

2

0

High-throughput

0.585

High

117235

K7EJH0
Kinetochore protein Spc24

1

1

High-throughput

0.575

High

1433055

U3KQ54
HCG2044777

1

1

High-throughput

0.575

High

1399444

WDFY2
WD repeat and FYVE domain-containing protein 2

2

2

High-throughput

0.574

High

251809

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

1

1

High-throughput

0.536

High

445258

S10A6
Protein S100-A6

1

2

High-throughput

0.536

High

682609

S100P
Protein S100-P

1

2

High-throughput

0.536

High

923636

TTC3
E3 ubiquitin-protein ligase TTC3

1

1

High-throughput

0.536

High

1433053

SALL2
Sal-like protein 2

1

1

High-throughput

0.536

High

1358240

SKA2
Spindle and kinetochore-associated protein 2

1

0

Small-scale

0.529

High

224169

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

1

1

High-throughput

0.515

High

156341

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

1

0

High-throughput

0.513

High

326035

UBR5
E3 ubiquitin-protein ligase UBR5

1

0

High-throughput

0.513

High

388296

GLPA
Glycophorin-A

1

0

High-throughput

0.513

High

539639

PYGM
Glycogen phosphorylase, muscle form

1

0

High-throughput

0.513

High

551260

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.513

High

714423

PML
Protein PML

1

0

High-throughput

0.513

High

761875

HSP74
Heat shock 70 kDa protein 4

1

0

High-throughput

0.513

High

773018

MYH9
Myosin-9

1

0

High-throughput

0.513

High

922036

COPA
Coatomer subunit alpha

1

0

High-throughput

0.513

High

946531

YBEY
Endoribonuclease YbeY

1

0

High-throughput

0.513

High

1066490

RBBP4
Histone-binding protein RBBP4

1

0

High-throughput

0.513

High

1226005

ICE2
Little elongation complex subunit 2

1

0

High-throughput

0.513

High

1323689

K2C78
Keratin, type II cytoskeletal 78

1

0

High-throughput

0.513

High

1405853

DNJC7
DnaJ homolog subfamily C member 7

1

0

High-throughput

0.513

High

1406985

NPAS1
Neuronal PAS domain-containing protein 1

1

0

High-throughput

0.513

High

1412915

NAA11
N-alpha-acetyltransferase 11

1

0

High-throughput

0.513

High

1417877

DUS16
Dual specificity protein phosphatase 16

1

0

High-throughput

0.513

High

1433043

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.513

High

1433047

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.513

High

1433048

PURG
Purine-rich element-binding protein gamma

1

0

High-throughput

0.513

High

1433054

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

High-throughput

0.513

High

167395

KLF11
Krueppel-like factor 11

1

0

High-throughput

0.493

High

641308

PGS1
Biglycan

1

0

High-throughput

0.493

High

665712

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

1

0

High-throughput

0.493

High

856921

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.493

High

1382688

COQA1
Collagen alpha-1(XXVI) chain

1

0

High-throughput

0.493

High

706308

S10A2
Protein S100-A2

1

2

High-throughput

0.489

High

1381922

C102A
Coiled-coil domain-containing protein 102A

1

1

High-throughput

0.489

High

1096635

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.486

High

1364874

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

1

0

High-throughput

0.486

High

423157

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

344999

WIZ
Protein Wiz

1

1

High-throughput

0.479

High

1235079

ADNP2
Activity-dependent neuroprotector homeobox protein 2

1

4

High-throughput

0.479

High

1395205

CHAP1
Chromosome alignment-maintaining phosphoprotein 1

1

1

High-throughput

0.479

High

1396302

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

1

High-throughput

0.479

High

1432089

ADNP
Activity-dependent neuroprotector homeobox protein

1

1

High-throughput

0.479

High

1433041

ZN644
Zinc finger protein 644

1

1

High-throughput

0.479

High

1433044

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

1

High-throughput

0.479

High

404415

GCR
Glucocorticoid receptor

1

0

High-throughput

0.458

High

461930

HS90A
Heat shock protein HSP 90-alpha

1

0

Small-scale

0.458

High

686725

IVD
Isovaleryl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

831421

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

883686

CENPA
Histone H3-like centromeric protein A

1

0

High-throughput

0.458

High

1094735

CAF1A
Chromatin assembly factor 1 subunit A

1

0

High-throughput

0.458

High

1129745

MDC1
Mediator of DNA damage checkpoint protein 1

1

0

High-throughput

0.458

High

1132973

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

0

High-throughput

0.458

High

1204392

SGO1
Shugoshin 1

1

0

High-throughput

0.458

High

1212462

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.458

High

1277235

POGZ
Pogo transposable element with ZNF domain

1

0

High-throughput

0.458

High

1292973

AROS
Active regulator of SIRT1

1

0

High-throughput

0.458

High

1332180

SCAI
Protein SCAI

1

0

High-throughput

0.458

High

1418392

PCGF6
Polycomb group RING finger protein 6

1

0

High-throughput

0.458

High

1433049

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.458

High

1158183

MK14
Mitogen-activated protein kinase 14

1

0

High-throughput

0.426

High

1362052

DNS2B
Deoxyribonuclease-2-beta

1

0

High-throughput

0.426

High

793761

ETFB
Electron transfer flavoprotein subunit beta

2

0

High-throughput

0.328

High

253900

TPST2
Protein-tyrosine sulfotransferase 2

1

0

High-throughput

0.279

Low

1415467

NUP58
Nucleoporin p58/p45

1

0

High-throughput

0.268

Low

1433050

ICAM5
Intercellular adhesion molecule 5

1

0

High-throughput

0.268

Low

1433042

SG196
Protein O-mannose kinase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025