HitPredict

Interactor 1: PDLI1 (O00151)
PDZ and LIM domain protein 1 (C-terminal LIM domain protein 1) (Elfin) (LIM domain protein CLP-36)
Gene: PDLIM1

Interactor 2: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	38280479, 38223760
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003713 - transcription coactivator activity GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 329 Hs			1 504
+	Hs
		1295737 PDLI2_HUMAN (5-316): 4.7e-40: 145: 29.53		WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42
+	Hs
		808317 SYNP2_HUMAN (6-174): 4.49e-30: 122: 24.56		NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26
+	Mm
		809071 SNTA1_MOUSE (4-266): 4.67e-26: 109: 13.41		YAP1_MOUSE (35-504): 1.41e-115: 351: 91.70
+	Hs
		125735 PDLI7_HUMAN (88-312): 2.86e-09: 59.8: 13.12		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Mm
		1143429 DLG4_MOUSE (1-87): 1e-19: 91.8: 25.53		NED4L_MOUSE (4-504): 5.54e-115: 364: 19.73
+	Mm
		93273 DLG4_MOUSE (1-87): 1e-19: 91.8: 25.53		E9PXB7_MOUSE (8-504): 1.1e-114: 359: 19.11
+	Hs
		200183 TGFI1_HUMAN (226-321): 4.82e-12: 68.4: 26.00		ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17
+	Mm
		1143674 TGFI1_MOUSE (253-315): 3.8e-11: 65.7: 25.40		ITCH_MOUSE (2-504): 2.6e-119: 372: 14.36
+	Hs
		1299602 MAGI1_HUMAN (2-267): 7e-12: 68.7: 12.59		NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73
+	Hs
		200184 TGFI1_HUMAN (226-321): 4.82e-12: 68.4: 26.00		NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73
+	Hs
		200166 TGFI1_HUMAN (226-321): 4.82e-12: 68.4: 26.00		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		808847 PDLI5_HUMAN (60-312): 1.59e-10: 64.1: 12.50		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		808955 PDLI7_HUMAN (88-312): 2.86e-09: 59.8: 13.12		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		200165 TGFI1_HUMAN (226-321): 4.82e-12: 68.4: 26.00		NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26
+	Hs
		808283 PDLI7_HUMAN (88-312): 2.86e-09: 59.8: 13.12		NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26
+	Hs
		1033852 SNTA1_HUMAN (5-258): 2.28e-29: 119: 14.23		WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83
+	Hs
		1293394 PDLI5_HUMAN (60-312): 1.59e-10: 64.1: 12.50		WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83
+	Hs
		1326752 PDLI7_HUMAN (88-312): 2.86e-09: 59.8: 13.12		WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83
+	Mm
		1143518 DLG4_MOUSE (1-87): 1e-19: 91.8: 25.53		MAGI3_MOUSE (69-287): 5.09e-40: 156: 21.68
+	Hs
		1300658 MAGI1_HUMAN (2-267): 7e-12: 68.7: 12.59		MAGI1_HUMAN (69-305): 1.87e-39: 155: 18.32