HitPredict

Interactor 1: SLY1 (Q24179)
Protein sly1 homolog
Gene: Slh

Interactor 2: GOSR2 (Q9VRL2)
Probable Golgi SNAP receptor complex member 2
Gene: Membrin

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0000149 - SNARE binding GO:0016192 - vesicle-mediated transport
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 639 Dm			1 216
+	Dm
		1172814 SLY1_DROME (1-639): 0: 616: 100.00		Q9W0N6_DROME (1-207): 4.15e-45: 151: 18.01
+	Hs
		160315 SCFD1_HUMAN (3-631): 0: 561: 56.90		GOSR2_HUMAN (1-214): 4.28e-60: 189: 41.12
+	Hs
		1358334 SCFD1_HUMAN (3-631): 0: 561: 56.90		VTI1A_HUMAN (1-213): 1.44e-49: 162: 17.05
+	Hs
		1358393 SCFD1_HUMAN (3-631): 0: 561: 56.90		VTI1B_HUMAN (1-193): 4.37e-43: 146: 14.87
+	Dm
		84847 SLY1_DROME (1-639): 0: 616: 100.00		B7Z0M0_DROME (111-193): 1.17e-14: 69.4: 14.46
+	At
		235516 VPS45_ARATH (10-634): 6.51e-139: 418: 19.46		VTI12_ARATH (1-213): 6.41e-61: 191: 16.51
+	Hs
		1383309 VPS45_HUMAN (27-638): 6.62e-149: 444: 20.97		VTI1A_HUMAN (1-213): 1.44e-49: 162: 17.05
+	At
		235517 VPS45_ARATH (10-634): 6.51e-139: 418: 19.46		VTI11_ARATH (1-195): 4.7e-57: 181: 15.08
+	Hs
		1448938 VPS45_HUMAN (27-638): 6.62e-149: 444: 20.97		VTI1B_HUMAN (1-193): 4.37e-43: 146: 14.87
+	Sc
		807876 VPS45_YEAST (20-628): 1.98e-122: 376: 16.59		VTI1_YEAST (3-197): 3.65e-38: 133: 18.09