Protein: VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B (Vesicle transport v-SNARE protein Vti1-like 1) (Vti1-rp1)

Gene: VTI1B
Organism: Homo sapiens
Interactions: 222
UniProt ID: Q9UEU0

Gene Ontology (top 5):
GO:0000149 - SNARE binding
GO:0005484 - SNAP receptor activity
GO:0005576 - extracellular region
GO:0005765 - lysosomal membrane
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1459042

STX8
Syntaxin-8

11

20

Small-scale

0.979

High

189905

STX7
Syntaxin-7

8

20

Small-scale

0.967

High

1294855

STX12
Syntaxin-12

5

20

High-throughput

0.925

High

226247

STX6
Syntaxin-6

5

20

Small-scale

0.922

High

278577

VAMP4
Vesicle-associated membrane protein 4

4

20

Small-scale

0.903

High

1154778

VAMP3
Vesicle-associated membrane protein 3

4

20

High-throughput

0.903

High

1129900

EPN4
Clathrin interactor 1

4

3

High-throughput

0.896

High

1087330

STX4
Syntaxin-4

3

20

High-throughput

0.871

High

249908

STX10
Syntaxin-10

3

20

High-throughput

0.861

High

280365

SC22B
Vesicle-trafficking protein SEC22b

2

20

High-throughput

0.811

High

328757

VAMP5
Vesicle-associated membrane protein 5

2

20

High-throughput

0.811

High

1452321

SCN3B
Sodium channel regulatory subunit beta-3

3

0

High-throughput

0.811

High

746226

STX2
Syntaxin-2

2

20

High-throughput

0.783

High

1159653

STX1A
Syntaxin-1A

2

20

High-throughput

0.783

High

908061

VAMP7
Vesicle-associated membrane protein 7

2

20

Small-scale

0.754

High

933069

SNAA
Alpha-soluble NSF attachment protein

6

13

High-throughput

0.736

High

1339581

STXB6
Syntaxin-binding protein 6

2

1

High-throughput

0.726

High

1213729

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

4

1

High-throughput

0.698

High

1242969

S39A4
Zinc transporter ZIP4

4

1

High-throughput

0.691

High

1454885

STX18
Syntaxin-18

4

5

High-throughput

0.691

High

1310701

TRI59
Tripartite motif-containing protein 59

4

0

High-throughput

0.668

High

220518

RNF13
E3 ubiquitin-protein ligase RNF13

3

3

High-throughput

0.667

High

334932

IPO7
Importin-7

3

1

High-throughput

0.667

High

890168

EI2BB
Translation initiation factor eIF2B subunit beta

3

2

High-throughput

0.667

High

1095953

EI2BE
Translation initiation factor eIF2B subunit epsilon

3

2

High-throughput

0.667

High

1124238

EI2BA
Translation initiation factor eIF2B subunit alpha

3

2

High-throughput

0.667

High

1399505

IPO9
Importin-9

3

1

High-throughput

0.667

High

1407053

SNAG
Gamma-soluble NSF attachment protein

3

13

High-throughput

0.667

High

1439048

CWC22
Pre-mRNA-splicing factor CWC22 homolog

3

1

High-throughput

0.667

High

1447974

EI2BG
Translation initiation factor eIF2B subunit gamma

3

1

High-throughput

0.667

High

1448938

VPS45
Vacuolar protein sorting-associated protein 45

3

10

High-throughput

0.667

High

1459038

EI2BD
Translation initiation factor eIF2B subunit delta

3

2

High-throughput

0.667

High

286734

STX11
Syntaxin-11

3

20

High-throughput

0.662

High

1086137

ASPH
Aspartyl/asparaginyl beta-hydroxylase

3

1

High-throughput

0.662

High

1093599

TRDN
Triadin

3

4

High-throughput

0.662

High

60438

NBAS
NBAS subunit of NRZ tethering complex

3

0

High-throughput

0.638

High

126198

AP3B1
AP-3 complex subunit beta-1

3

0

High-throughput

0.638

High

351183

ECD
Protein ecdysoneless homolog

3

0

High-throughput

0.638

High

1158090

2A5E
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform

3

0

High-throughput

0.638

High

1212970

STXB5
Syntaxin-binding protein 5

3

0

High-throughput

0.638

High

1389805

DTBP1
Dysbindin

3

0

High-throughput

0.638

High

1407825

HAUS7
HAUS augmin-like complex subunit 7

3

0

High-throughput

0.638

High

1459041

ACINU
Apoptotic chromatin condensation inducer in the nucleus

3

0

High-throughput

0.638

High

1459044

TN13B
Tumor necrosis factor ligand superfamily member 13B

3

0

High-throughput

0.638

High

1459046

AP3M1
AP-3 complex subunit mu-1

3

0

High-throughput

0.638

High

1349346

TBC15
TBC1 domain family member 15

3

0

High-throughput

0.634

High

340687

STABP
STAM-binding protein

2

1

High-throughput

0.628

High

857197

NSF
Vesicle-fusing ATPase

2

5

High-throughput

0.628

High

940574

AP1S2
AP-1 complex subunit sigma-2

2

1

High-throughput

0.628

High

1386298

HAUS1
HAUS augmin-like complex subunit 1

2

1

High-throughput

0.628

High

1390685

STALP
AMSH-like protease

2

1

High-throughput

0.628

High

564505

CFTR
Cystic fibrosis transmembrane conductance regulator

2

1

Small-scale

0.628

High

932608

PTN5
Tyrosine-protein phosphatase non-receptor type 5

2

1

High-throughput

0.628

High

1097915

STX5
Syntaxin-5

1

20

Small-scale

0.618

High

1211020

CE170
Centrosomal protein of 170 kDa

2

1

High-throughput

0.611

High

1208762

CL12A
C-type lectin domain family 12 member A

3

4

High-throughput

0.609

High

1331273

ARL10
ADP-ribosylation factor-like protein 10

3

3

High-throughput

0.609

High

253176

MOT2
Monocarboxylate transporter 2

2

2

High-throughput

0.606

High

456025

ASGR2
Asialoglycoprotein receptor 2

2

3

High-throughput

0.606

High

1328220

JAGN1
Protein jagunal homolog 1

2

1

High-throughput

0.606

High

1447174

S35C2
Solute carrier family 35 member C2

2

2

High-throughput

0.606

High

1459045

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

3

High-throughput

0.606

High

1355942

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

2

0

High-throughput

0.602

High

1459040

RABX5
Rab5 GDP/GTP exchange factor

2

0

High-throughput

0.602

High

516730

VSIG8
V-set and immunoglobulin domain-containing protein 8

2

0

High-throughput

0.596

High

845842

MUC18
Cell surface glycoprotein MUC18

1

0

High-throughput

0.586

High

183527

CASC3
Protein CASC3

2

0

High-throughput

0.585

High

273237

CAND2
Cullin-associated NEDD8-dissociated protein 2

2

0

High-throughput

0.585

High

536299

PPAL
Lysosomal acid phosphatase

2

0

High-throughput

0.585

High

807607

IF4A3
Eukaryotic initiation factor 4A-III

2

0

High-throughput

0.585

High

553377

FCGR1
High affinity immunoglobulin gamma Fc receptor I

2

0

High-throughput

0.580

High

1242820

RNK
Ribonuclease kappa

2

0

High-throughput

0.580

High

1434957

REEP4
Receptor expression-enhancing protein 4

2

0

High-throughput

0.580

High

230457

CREB3
Cyclic AMP-responsive element-binding protein 3

2

1

High-throughput

0.576

High

1331872

SYT2
Synaptotagmin-2

2

0

High-throughput

0.576

High

1383502

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

2

0

High-throughput

0.576

High

1100732

STX3
Syntaxin-3

1

20

High-throughput

0.575

High

1414887

VAMP8
Vesicle-associated membrane protein 8

1

20

Small-scale

0.575

High

688640

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

2

4

High-throughput

0.553

High

1109086

AQP6
Aquaporin-6

2

6

High-throughput

0.553

High

1329451

KASH5
Protein KASH5

2

1

High-throughput

0.553

High

1352545

GPX8
Probable glutathione peroxidase 8

2

1

High-throughput

0.553

High

950427

KR107
Keratin-associated protein 10-7

1

0

High-throughput

0.549

High

180094

BET1
BET1 homolog

1

20

High-throughput

0.536

High

302092

SEGN
Secretagogin

1

1

High-throughput

0.536

High

343496

SNP29
Synaptosomal-associated protein 29

1

9

High-throughput

0.536

High

540731

LAMP1
Lysosome-associated membrane glycoprotein 1

1

4

High-throughput

0.536

High

1053845

KDSR
3-ketodihydrosphingosine reductase

1

2

High-throughput

0.536

High

1358393

SCFD1
Sec1 family domain-containing protein 1

1

10

High-throughput

0.536

High

1383314

VTI1A
Vesicle transport through interaction with t-SNAREs homolog 1A

1

5

High-throughput

0.536

High

1399071

TMM74
Transmembrane protein 74

1

1

High-throughput

0.536

High

1450279

EXOC1
Exocyst complex component 1

1

1

High-throughput

0.536

High

1452967

USE1
Vesicle transport protein USE1

1

4

High-throughput

0.536

High

923478

PTTG
Pituitary tumor-transforming gene 1 protein-interacting protein

2

1

High-throughput

0.533

High

269979

AUXI
Auxilin

1

0

High-throughput

0.513

High

300702

KRT37
Keratin, type I cuticular Ha7

1

0

High-throughput

0.513

High

1026263

CLH1
Clathrin heavy chain 1

1

0

High-throughput

0.513

High

1110752

DCTN2
Dynactin subunit 2

1

0

High-throughput

0.513

High

1272004

CENPQ
Centromere protein Q

1

0

High-throughput

0.513

High

1367911

THRSP
Thyroid hormone-inducible hepatic protein

1

0

High-throughput

0.513

High

1436385

MANS1
MANSC domain-containing protein 1

1

0

High-throughput

0.513

High

1452885

GTSE1
G2 and S phase-expressed protein 1

1

0

High-throughput

0.513

High

1459048

PKHM1
Pleckstrin homology domain-containing family M member 1

1

0

Small-scale

0.513

High

1363245

AQP3
Aquaporin-3

1

5

High-throughput

0.489

High

386331

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

1

High-throughput

0.481

High

926865

VMAT1
Chromaffin granule amine transporter

1

1

High-throughput

0.481

High

1447906

SAR1A
Small COPII coat GTPase SAR1A

1

2

High-throughput

0.481

High

126855

RHOD
Rho-related GTP-binding protein RhoD

1

17

High-throughput

0.479

High

376055

RASK
GTPase KRas

1

4

High-throughput

0.479

High

466511

RHOC
Rho-related GTP-binding protein RhoC

1

13

High-throughput

0.479

High

508774

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

2

High-throughput

0.479

High

562464

LAMP2
Lysosome-associated membrane glycoprotein 2

1

4

High-throughput

0.479

High

581355

RAC2
Ras-related C3 botulinum toxin substrate 2

1

13

High-throughput

0.479

High

631007

RAB4A
Ras-related protein Rab-4A

1

3

High-throughput

0.479

High

631533

RAB5A
Ras-related protein Rab-5A

1

4

High-throughput

0.479

High

901084

RAB5C
Ras-related protein Rab-5C

1

4

High-throughput

0.479

High

901647

RAB7A
Ras-related protein Rab-7a

1

7

High-throughput

0.479

High

902127

RAB9A
Ras-related protein Rab-9A

1

4

High-throughput

0.479

High

953736

RAC3
Ras-related C3 botulinum toxin substrate 3

1

14

High-throughput

0.479

High

955719

CDC42
Cell division control protein 42 homolog

1

14

High-throughput

0.479

High

962597

RHOA
Transforming protein RhoA

1

15

High-throughput

0.479

High

978378

RHOB
Rho-related GTP-binding protein RhoB

1

16

High-throughput

0.479

High

988794

RAC1
Ras-related C3 botulinum toxin substrate 1

1

14

High-throughput

0.479

High

1015880

RHOG
Rho-related GTP-binding protein RhoG

1

13

High-throughput

0.479

High

1091847

TP4A2
Protein tyrosine phosphatase type IVA 2

1

3

Small-scale

0.479

High

1233550

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

1276357

ATG9A
Autophagy-related protein 9A

1

1

High-throughput

0.479

High

1334610

RN149
E3 ubiquitin-protein ligase RNF149

1

3

High-throughput

0.479

High

1454278

VPS18
Vacuolar protein sorting-associated protein 18 homolog

1

6

High-throughput

0.479

High

1459037

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1459043

LAMP3
Lysosome-associated membrane glycoprotein 3

1

4

High-throughput

0.479

High

178430

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

218917

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

219422

TNF12
Tumor necrosis factor ligand superfamily member 12

1

0

High-throughput

0.458

High

290192

OFD1
Centriole and centriolar satellite protein OFD1

1

0

High-throughput

0.458

High

583113

VATB1
V-type proton ATPase subunit B, kidney isoform

1

0

High-throughput

0.458

High

754601

S10A3
Protein S100-A3

1

0

High-throughput

0.458

High

897416

CDK7
Cyclin-dependent kinase 7

1

0

High-throughput

0.458

High

899620

TCPD
T-complex protein 1 subunit delta

1

0

High-throughput

0.458

High

1041347

CAV1
Caveolin-1

1

0

High-throughput

0.458

High

1139296

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

0

High-throughput

0.458

High

1227635

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.458

High

1249294

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1253006

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.458

High

1279920

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

0

High-throughput

0.458

High

1362013

RFFL
E3 ubiquitin-protein ligase rififylin

1

0

Small-scale

0.458

High

1367501

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1383272

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.458

High

1429468

PAIP1
Polyadenylate-binding protein-interacting protein 1

1

0

High-throughput

0.458

High

1448921

DUS22
Dual specificity protein phosphatase 22

1

0

High-throughput

0.458

High

1450007

LMBD1
Lysosomal cobalamin transport escort protein LMBD1

1

0

High-throughput

0.458

High

1458219

NCDN
Neurochondrin

1

0

High-throughput

0.458

High

800587

VATA
V-type proton ATPase catalytic subunit A

1

1

High-throughput

0.445

High

943558

G6PT2
Glucose-6-phosphate exchanger SLC37A1

1

3

High-throughput

0.445

High

1034080

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

1

High-throughput

0.445

High

1208135

S35D3
Solute carrier family 35 member D3

1

1

High-throughput

0.445

High

1251198

ZNT10
Calcium/manganese antiporter SLC30A10

1

11

High-throughput

0.445

High

1310975

ZNT8
Proton-coupled zinc antiporter SLC30A8

1

11

High-throughput

0.445

High

1346822

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

11

High-throughput

0.445

High

1352582

G6PT3
Glucose-6-phosphate exchanger SLC37A2

1

3

High-throughput

0.445

High

1352901

TP4AP
Short transient receptor potential channel 4-associated protein

1

1

High-throughput

0.445

High

1439129

ANKH
Mineralization regulator ANKH

1

1

High-throughput

0.445

High

1102464

BIK
Bcl-2-interacting killer

1

1

High-throughput

0.439

High

1060813

ACK1
Activated CDC42 kinase 1

1

0

High-throughput

0.438

High

1132355

GOGB1
Golgin subfamily B member 1

1

0

High-throughput

0.438

High

601481

RHOQ
Rho-related GTP-binding protein RhoQ

1

15

High-throughput

0.437

High

696770

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

849046

PTN9
Tyrosine-protein phosphatase non-receptor type 9

1

1

Small-scale

0.437

High

1005212

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.437

High

1294281

GOLI
E3 ubiquitin-protein ligase RNF130

1

4

High-throughput

0.437

High

1433560

RHOJ
Rho-related GTP-binding protein RhoJ

1

15

High-throughput

0.437

High

1450125

OTULL
Inactive ubiquitin thioesterase OTULINL

1

1

High-throughput

0.437

High

90716

WASH3
Putative WAS protein family homolog 3

1

0

High-throughput

0.426

High

337148

NPT2B
Sodium-dependent phosphate transport protein 2B

1

0

High-throughput

0.426

High

935244

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.426

High

943150

STX17
Syntaxin-17

1

0

Small-scale

0.426

High

1329205

S15A4
Solute carrier family 15 member 4

1

0

High-throughput

0.426

High

1334290

S38A9
Neutral amino acid transporter 9

1

0

High-throughput

0.426

High

71876

A8MZH8
PTTG1 interacting protein

1

1

High-throughput

0.407

High

1181015

TR16L
Tripartite motif-containing protein 16-like protein

1

1

High-throughput

0.407

High

1242265

NPAL3
NIPA-like protein 3

1

3

High-throughput

0.407

High

1396586

C170L
Cep170-like protein

1

1

High-throughput

0.407

High

1417643

S46A2
Solute carrier family 46 member 2

1

2

High-throughput

0.407

High

1459049

5MP1
eIF5-mimic protein 1

1

1

High-throughput

0.407

High

604759

UBF1
Nucleolar transcription factor 1

3

0

High-throughput

0.347

High

1123163

FHL2
Four and a half LIM domains protein 2

3

0

High-throughput

0.347

High

1236047

HPHL1
Ferroxidase HEPHL1

3

0

High-throughput

0.347

High

1249401

CWC27
Spliceosome-associated protein CWC27 homolog

3

0

High-throughput

0.347

High

1286480

DSG4
Desmoglein-4

3

0

High-throughput

0.347

High

1291745

SESD1
SEC14 domain and spectrin repeat-containing protein 1

3

0

High-throughput

0.347

High

1459047

CCDC9
Coiled-coil domain-containing protein 9

3

0

High-throughput

0.347

High

946601

EVA1C
Protein eva-1 homolog C

3

0

High-throughput

0.339

High

749818

CADH5
Cadherin-5

2

0

High-throughput

0.328

High

1108413

MED21
Mediator of RNA polymerase II transcription subunit 21

2

0

High-throughput

0.328

High

1323899

SYNE4
Nesprin-4

2

0

High-throughput

0.327

High

549909

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

0

High-throughput

0.316

High

584690

MCP
Membrane cofactor protein

2

0

High-throughput

0.316

High

1361466

TM234
Transmembrane protein 234

2

0

High-throughput

0.316

High

1414234

CRUM3
Protein crumbs homolog 3

2

0

High-throughput

0.316

High

1447075

MANBL
Protein MANBAL

2

0

High-throughput

0.316

High

1449810

TM14B
Transmembrane protein 14B

2

0

High-throughput

0.316

High

1451125

TMM51
Transmembrane protein 51

2

0

High-throughput

0.316

High

789241

NUP62
Nuclear pore glycoprotein p62

2

0

High-throughput

0.313

High

1278645

HEAT3
HEAT repeat-containing protein 3

2

0

High-throughput

0.313

High

1389615

SAAL1
Protein SAAL1

2

0

High-throughput

0.313

High

1438771

GPR35
G-protein coupled receptor 35

1

0

High-throughput

0.282

High

240120

KPRB
Phosphoribosyl pyrophosphate synthase-associated protein 2

1

0

High-throughput

0.279

Low

1407122

MDFI
MyoD family inhibitor

1

0

High-throughput

0.279

Low

1418962

WNK3
Serine/threonine-protein kinase WNK3

1

0

High-throughput

0.279

Low

1436407

PAAT
ATPase PAAT

1

0

High-throughput

0.279

Low

1459039

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.279

Low

248534

OR7C2
Olfactory receptor 7C2

1

0

High-throughput

0.249

Low

294479

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

692830

CALL3
Calmodulin-like protein 3

1

0

High-throughput

0.249

Low

841272

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.249

Low

1387287

HDA11
Histone deacetylase 11

1

0

High-throughput

0.249

Low

1391371

CFA36
Cilia- and flagella-associated protein 36

1

0

High-throughput

0.249

Low

1459036

CS025
UPF0449 protein C19orf25

1

0

High-throughput

0.249

Low

1211087

PR15B
Protein phosphatase 1 regulatory subunit 15B

1

0

High-throughput

0.232

Low

1339403

GP156
Probable G-protein coupled receptor 156

1

0

High-throughput

0.232

Low

1436008

PACC1
Proton-activated chloride channel

1

0

High-throughput

0.232

Low

1458402

S53A1
Solute carrier family 53 member 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025