Protein: ACTG
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]

Gene: ACTG, Actg1
Organism: Mus musculus
Interactions: 43
UniProt ID: P63260

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001738 - morphogenesis of a polarized epithelium
GO:0005200 - structural constituent of cytoskeleton
GO:0005522 - profilin binding
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

993111

EED
Polycomb protein EED

2

13

Small-scale

0.737

High

993114

COTL1
Coactosin-like protein

1

13

Small-scale

0.621

High

968069

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

11

High-throughput

0.618

High

993089

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

8

Small-scale

0.618

High

993092

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

17

Small-scale

0.618

High

993102

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

18

Small-scale

0.618

High

993108

EP400
E1A-binding protein p400

1

20

Small-scale

0.618

High

993121

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

9

High-throughput

0.590

High

267264

CSKP
Peripheral plasma membrane protein CASK

1

4

Small-scale

0.575

High

993094

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

10

Small-scale

0.575

High

993109

KAT5
Histone acetyltransferase KAT5

2

11

Small-scale

0.571

High

993091

KCMA1
Calcium-activated potassium channel subunit alpha-1

1

8

High-throughput

0.536

High

993117

ITA2B
Integrin alpha-IIb

1

3

High-throughput

0.501

High

97403

PRRT2
Proline-rich transmembrane protein 2

1

2

High-throughput

0.479

High

876520

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C]

1

3

Small-scale

0.479

High

947657

NPHP4
Nephrocystin-4

1

3

High-throughput

0.479

High

989939

1433Z
14-3-3 protein zeta/delta

1

17

High-throughput

0.479

High

993096

RN123
E3 ubiquitin-protein ligase RNF123

1

4

Small-scale

0.479

High

993099

TFE3
Transcription factor E3

1

4

High-throughput

0.479

High

993104

KLH17
Kelch-like protein 17

1

9

Small-scale

0.479

High

993112

FBX32
F-box only protein 32

1

6

High-throughput

0.479

High

993119

AICDA
Single-stranded DNA cytosine deaminase

1

1

Small-scale

0.479

High

993090

RGS14
Regulator of G-protein signaling 14

1

0

High-throughput

0.458

High

204792

ST2B1
Sulfotransferase 2B1

1

1

Small-scale

0.445

High

663079

GRIA2
Glutamate receptor 2

1

4

Small-scale

0.445

High

993093

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

8

High-throughput

0.445

High

993097

DLG4
Disks large homolog 4

1

4

Small-scale

0.445

High

993101

GIT1
ARF GTPase-activating protein GIT1

1

20

Small-scale

0.445

High

993122

KCNQ2
Potassium voltage-gated channel subfamily KQT member 2

1

6

Small-scale

0.445

High

59600

A2AM57
Inversin

1

7

High-throughput

0.437

High

993095

MKS1
Tectonic-like complex member MKS1

1

1

High-throughput

0.437

High

993103

TEDC2
Tubulin epsilon and delta complex protein 2

1

1

High-throughput

0.437

High

993105

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

6

High-throughput

0.437

High

993106

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

2

High-throughput

0.437

High

993107

CBAR1
CBY1-interacting BAR domain-containing protein 1

1

1

High-throughput

0.437

High

993110

TTC23
Tetratricopeptide repeat protein 23

1

1

High-throughput

0.437

High

993113

RN138
E3 ubiquitin-protein ligase RNF138

1

19

Small-scale

0.437

High

993115

RING2
E3 ubiquitin-protein ligase RING2

1

20

Small-scale

0.437

High

993116

Q9D2V3
Progranulin

1

1

High-throughput

0.437

High

993118

NPHP1
Nephrocystin-1

1

1

High-throughput

0.437

High

993098

SYPH
Synaptophysin

1

0

Small-scale

0.426

High

993120

KCND2
A-type voltage-gated potassium channel KCND2

1

0

Small-scale

0.426

High

993100

PKHG5
Pleckstrin homology domain-containing family G member 5

1

14

Small-scale

0.408

High


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Last updated: 11Aug2025