Interactor 1: CUL1 (Q24311)
Cullin homolog 1 (Lin-19 homolog protein)
Gene: CUL1
Interactor 2: UBA3 (Q9V6U8)
Nedd8-activating enzyme E1 catalytic subunit (EC 6.2.1.64) (Ubiquitin-activating enzyme 3 homolog)
Gene: UBA3
Species: Drosophila melanogaster
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 0.60 | 0.501 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 21931660 |
| Identification Methods | enzymatic study |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0045879 - negative regulation of smoothened signaling pathway |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
