HitPredict

Interactor 1: TBA1A (Q71U36)
Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]
Gene: TUBA1A

Interactor 2: WDR6 (Q9NNW5)
tRNA (34-2'-O)-methyltransferase regulator WDR6 (WD repeat-containing protein 6)
Gene: WDR6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	27291054
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 451 Hs			1 1121
+	Hs
		933394 TBA1B_HUMAN (1-440): 0: 715: 99.55		FBW1A_HUMAN (30-284): 7.71e-34: 140: 13.41
+	Hs
		1175259 TBA1A_HUMAN (1-440): 0: 713: 100.00		FBW1A_HUMAN (30-284): 7.71e-34: 140: 13.41
+	Hs
		428508 TBB5_HUMAN (1-439): 0: 695: 40.77		FBW1A_HUMAN (30-284): 7.71e-34: 140: 13.41
+	Hs
		934030 TBB4B_HUMAN (1-437): 0: 693: 40.50		FBW1A_HUMAN (30-284): 7.71e-34: 140: 13.41
+	Hs
		1281347 TBA1C_HUMAN (1-451): 0: 726: 98.00		FBXW7_HUMAN (603-914): 3.98e-13: 76: 13.75
+	Hs
		1202779 TBA1C_HUMAN (1-451): 0: 726: 98.00		WDR5B_HUMAN (390-646): 2.24e-09: 62.2: 12.78
+	Hs
		903472 TBA1C_HUMAN (1-451): 0: 726: 98.00		WDR5_HUMAN (390-646): 7.51e-09: 60.7: 13.53
+	Hs
		903114 TBA4A_HUMAN (1-450): 0: 717: 96.00		WDR5_HUMAN (390-646): 7.51e-09: 60.7: 13.53
+	Hs
		1174998 TBA1A_HUMAN (1-440): 0: 713: 100.00		WDR5B_HUMAN (390-646): 2.24e-09: 62.2: 12.78
+	Hs
		428163 TBB5_HUMAN (1-439): 0: 695: 40.77		TBL3_HUMAN (12-118): 1.81e-11: 70.5: 7.34
+	Hs
		428123 TBB5_HUMAN (1-439): 0: 695: 40.77		WDR5_HUMAN (390-646): 7.51e-09: 60.7: 13.53
+	Hs
		903115 TBB4B_HUMAN (1-437): 0: 693: 40.50		WDR5_HUMAN (390-646): 7.51e-09: 60.7: 13.53